Kooperativer Bibliotheksverbund

UID:

Format: XIV, 687 S. , Ill., graph. Darst., Kt. , 27 cm

ISBN: 1461409799 , 9781461409793

Series Statement: Advances in experimental medicine and biology 726

Content: Viruses: sophisticated biological machines / M.G. Rossmann and V.B. Rao -- F(1)-ATPase: A prototypical rotary molecular motor / K. Kinosita, Jr. -- Principles of virus structural organization / B.V. Prasad and M.F. Schmid -- Reconstructing virus structures from nanometer to near-atomic resolutions with cryo-electron microscopy and tomography / J. Chang ... [et al.] -- Contractile tail machines of bacteriophages / P.G. Leiman and M.M. Shneider -- Long noncontractile tail machines of bacteriophages / A.R. Davidson ... [et al.] -- Short noncontractile tail machines: adsorption and DNA delivery by podoviruses / S.R. Casjens and I.J. Molineux -- Infection of cells by alphaviruses / D.T. Brown and R. Hernandez -- Influenza virus entry / M. Luo -- Molecular mechanisms of HIV entry / C.B. Wilen, J.C. Tilton and R.W. Doms -- Bunyavirus: structure and replication / T.S. Guu, W. Zheng and Y.J. Tao -- Viral polymerases / K.H. Choi -- Chaperonin-mediated folding of viral proteins / Z.L. Hildenbrand and R.A. Bernal -- Building the machines: scaffolding protein functions during bacteriophage morphogenesis / P.E. Prevelige and B.A. Fane -- Bacteriophage HK97 capsid assembly and maturation / R.W. Hendrix and J.E. Johnson -- Lipid-containing viruses: Bacteriophage PRD1 assembly / S.J. Butcher, V. Manole and N.J. Karhu -- Assembly of large icosahedral double-stranded RNA viruses / M.M. Poranen and D.H. Bamford -- The papillomavirus virion: a machine built to hide molecular Achilles' heels / C.B. Buck and B.L. Trus -- Procapsid assembly, maturation, nuclear exit: dynamic steps in the production of infectious herpesvirions / G. Cardone ... [et al.] -- Assembly and architecture of HIV / B.K. Ganser-Pornillos, M. Yeager and O. Pornillos -- Condensed genome structure / L.W. Black and J.A. Thomas -- The bacteriophage DNA packaging machine / M. Feiss and V.B. Rao -- The dsDNA packaging motor in Bacteriophage o29 / M.C. Morais -- Single-molecule studies of viral DNA packaging / Y.R. Chemla and D.E. Smith -- Genome gating in tailed bacteriophage capsids / P. Tavares, S. Zinn-Justin and E.V. Orlova -- Packaging in dsRNA Viruses / L. Mindich -- Mechanism of RNA packaging motor / E.J. Mancini and R. Tuma -- Helical viruses / G. Stubbs and A. Kendall

Note: Formerly CIP Uk. - Includes bibliographical references and index , Viruses: sophisticated biological machines , F(1)-ATPase: A prototypical rotary molecular motor , Principles of virus structural organization , Reconstructing virus structures from nanometer to near-atomic resolutions with cryo-electron microscopy and tomography , Contractile tail machines of bacteriophages , Long noncontractile tail machines of bacteriophages , Short noncontractile tail machines: adsorption and DNA delivery by podoviruses , Infection of cells by alphaviruses , Influenza virus entry , Molecular mechanisms of HIV entry , Bunyavirus: structure and replication , Viral polymerases , Chaperonin-mediated folding of viral proteins , Building the machines: scaffolding protein functions during bacteriophage morphogenesis , Bacteriophage HK97 capsid assembly and maturation , Lipid-containing viruses: Bacteriophage PRD1 assembly , Assembly of large icosahedral double-stranded RNA viruses , The papillomavirus virion: a machine built to hide molecular Achilles' heels , Procapsid assembly, maturation, nuclear exit: dynamic steps in the production of infectious herpesvirions , Assembly and architecture of HIV , Condensed genome structure , The bacteriophage DNA packaging machine , The dsDNA packaging motor in Bacteriophage o29 , Single-molecule studies of viral DNA packaging , Genome gating in tailed bacteriophage capsids , Packaging in dsRNA Viruses , Mechanism of RNA packaging motor , Helical viruses

Additional Edition: 9781461409809

Additional Edition: Online-Ausg. Rossmann, Michael G. Viral Molecular Machines Boston, MA : Springer US, 2012 9781461409809

Language: English

Subjects: Medicine

URL: Cover

URL: Volltext

URL: http://site.ebrary.com/id/10530921

UID:

Format: XIV, 687 S. : Ill., graph. Darst.

ISBN: 9781461409793 , 1461409799

Series Statement: Advances in experimental medicine and biology 726

Additional Edition: Erscheint auch als Online-Ausgabe 9781461409809

Language: English

URL: Inhaltsverzeichnis

UID:

Format: Online-Ressource (684 p.)

Edition: Online-Ausg. 2011 Electronic reproduction; Available via World Wide Web

ISBN: 9781461409793

Series Statement: Advances in Experimental Medicine and Biology, 726 v.726

Content: This book will contain a series of solicited chapters that concern with the molecular machines required by viruses to perform various essential functions of virus life cycle. The first three chapters (Introduction, Molecular Machines and Virus Architecture) introduce the reader to the best known molecular machines and to the structure of viruses. The remainder of the book will examine in detail various stages of the viral life cycle. Beginning with the viral entry into a host cell, the book takes the reader through replication of the genome, synthesis and assembly of viral structural component

Note: Description based upon print version of record , Viral Molecular Machines; Acknowledgment; Contents; Contributors; Chapter 1: Viruses: Sophisticated Biological Machines; Chapter 2: F 1 -ATPase: A Prototypical Rotary Molecular Motor; 2.1 A Rotary Molecular Machine; 2.2 Rotary Mechanism; 2.2.1 Symmetry Considerations; 2.2.2 Kinetics of Chemo-Mechanical Coupling; 2.2.3 Binding Changes and ATP Synthesis; 2.2.4 Structural Basis of Rotation; 2.3 Spiral Rotations and Viral Machines; References; Chapter 3: Principles of Virus Structural Organization; 3.1 Introduction; 3.2 Structural Techniques; 3.3 Capsid Organization in Spherical Viruses , 3.3.1 Cubic Symmetry3.3.2 Icosahedral Capsid Organization; 3.3.3 Triangulation Numbers; 3.3.4 Classes of Icosahedra; 3.3.5 Icosahedral Asymmetric Unit and Quasi-Equivalent Subunits; 3.3.6 Pentavalent and Hexavalent Positions; 3.4 High-Resolution Structures of Spherical Viruses and Quasi-Equivalence Theory; 3.4.1 Conformational Switching; 3.4.2 Triangulated Lattice and Subunit Packing; 3.4.3 Capsid Assembly; 3.4.4 Scaffolds, Glue Proteins, and Cores; 3.4.4.1 "True" T = 7 Capsid Organization; 3.4.4.2 Scaffolding Protein; 3.4.4.3 The Portal; 3.4.4.4 Maturation and Expansion , 3.4.4.5 Glue Proteins3.4.4.6 Cores; 3.5 Helical Viruses; 3.6 Enveloped Viruses; 3.7 Conclusion; References; Chapter 4: Reconstructing Virus Structures from Nanometer to Near-Atomic Resolutions with Cryo-Electron Microscopy and Tomography; 4.1 Introduction; 4.2 Cryo-Electron Microscopy and Tomography; 4.3 Single-Particle Reconstruction Methods; 4.3.1 Reconstructing Icosahedral Viruses; 4.3.1.1 Initial Data Preparation; 4.3.1.2 Building an Initial Model; 4.3.1.3 Particle Orientation and Center Determination; Projection Matching; Common Lines; 4.3.1.4 Reconstructing a 3-D Volume , Fourier-Space ReconstructionsReal-Space Reconstruction (Back Projection); 4.3.1.5 Processing and Refining a 3-D Map; 4.3.1.6 Postprocessing of 3-D Volumes; Map Sharpening; Noncrystallographic Symmetry Averaging; Visualization and Segmentation; 4.3.1.7 Selected Examples of Near-Atomic Resolution Structures; 4.3.2 Reconstructing Particles Without Imposing Symmetry; 4.3.2.1 Initial Data Preparation; 4.3.2.2 Building an Initial Model; 4.3.2.3 Determining the Asymmetric Orientation; 4.3.2.4 Reconstructing Asymmetric Density Maps; 4.3.2.5 Selected Examples of Symmetry-Free Structures , 4.4 Tomographic Reconstruction Methods4.4.1 Specimen Preparation Considerations; 4.4.2 Cryo-ET Data Collection; 4.4.3 Processing the 2-D Data (Tilt Series); 4.4.4 Aligning and Averaging Subvolumes; 4.4.5 Classification of Subvolumes; 4.4.6 Selected Examples of Cryo-ET Reconstructions; 4.5 Data Validation and Interpretation; 4.5.1 Map Validation; 4.5.2 Segmenting Cryo-EM and Cryo-ET Maps; 4.5.3 Identifying Structural Features in a Density Map; 4.5.4 Model Fitting to Cryo-EM Density Maps; 4.5.5 Deriving Protein Models from Cryo-EM Density Maps; 4.5.6 De Novo Modeling , 4.6 Conclusion and Future Directions , Electronic reproduction; Available via World Wide Web

Additional Edition: 9781461409809

Additional Edition: 9781461409793

Additional Edition: Print version Viral Molecular Machines

Language: English

Keywords: Electronic books

URL: Volltext

URL: Volltext

URL: Volltext  (lizenzpflichtig)

UID:

Format: XIV, 687 S. , 29 b&w, 192 col.Ill., graph. Darst. , 24x16x4 cm

ISBN: 9781461409793 , 1461409799

Series Statement: Advances in experimental medicine and biology 726

Note: Hardback. - Literaturangaben

Language: English

URL: Kurzbeschreibung

URL: Ausführliche Beschreibung

URL: Inhaltsverzeichnis

UID:

Format: XIV, 687 Seiten , Ill., graph. Darst.

ISBN: 9781461409793

Series Statement: Advances in experimental medicine and biology 726

Language: English

UID:

Format: XIV, 687 S. , Ill., graph. Darst.

ISBN: 9781461409793 , 9781461409809

Series Statement: Advances in experimental medicine and biology 726

Language: English

URL: Inhaltsverzeichnis