Format:
Online-Ressource (X, 147 p. 25 illus., 13 illus. in color, digital)
ISBN:
9783642310171
Series Statement:
Current Topics in Microbiology and Immunology 361
Content:
This volume brings together contributions from experts in the field of Pasteurella research. Its covers areas such as comparative genomics, pathogenic mechanisms, bacterial proteomics, as well as a detailed description and analysis of PMT and its interaction with host tissues, cells, immune system, and signalling pathways.
Content:
This volume brings together contributions from experts in the field of Pasteurella research. It covers areas such as comparative genomics, pathogenic mechanisms, bacterial proteomics, as well as a detailed description and analysis of PMT and its interaction with host tissues, cells, immune system, and signalling pathways
Note:
Description based upon print version of record
,
Pasteurella multocida; Preface; Contents; Contributors; 216 Pasteurella multocida: Diseases and Pathogenesis; Abstract; 1…Non-Specific Disease Syndromes Caused by Pasteurella multocida; 2…Specific Disease Syndromes; 3…Avian Cholera; 4…Haemorrhagic Septicaemia; 5…Atrophic Rhinitis; 6…Snuffles of Rabbits; 7…Lower Respiratory Tract Infections of Ungulates; 8…Sporadic Septicaemias Involving Different Capsular Types; 9…Mechanisms of Pathogenesis: Cellular and Molecular Aspects; 10…Resistance to Host Innate Immunity; 11…Cell Adhesion and Invasion; 12…Other Virulence-Associated Factors
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AcknowledgmentsReferences; 203 Pathogenomics of Pasteurella multocida; Abstract; 1…Sequenced P. multocida Genomes; 2…Comparison of the Complete Genomes of Pm70 and 36950; 3…Analysis of the Incomplete Genome Sequences of Strains X73, VP161, Anand1P, Anand1G, P903, M1404 and P3480; 4…Plasmids Carried by P. multocida Strains; 5…Bacteriophages of P. multocida; 6…Whole-Genome Transcriptomic Analyses; 7…Proteomic Analyses; 8…Concluding Remarks; References; 202 The Key Surface Components of Pasteurella multocida: Capsule and Lipopolysaccharide; Abstract; 1…The Capsule of Pasteurella multocida
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2…Chemical Structure of Pasteurella multocida Capsules3…Genetics of Capsule Biosynthesis; 4…Regulation of Capsule Production; 5…The Role of Capsule in Virulence; 6…The Lipopolysaccharide of Pasteurella multocida; 7…The LPS Inner Core Structure; 8…Genetics and Assembly of the LPS Inner Core; 9…The LPS Outer Core; 10…The Role of LPS in Virulence; 11…The Role of LPS in Immunity; Acknowledgments; References; 204 Pasteurella Multocida and Immune Cells; Abstract; 1…Introduction; 1.1 How the Immune System Fights Bacterial Infections; 1.2 Bacterial Strategies of Immune Evasion
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2…Pasteurella multocida and Immune Cells2.1 Pasteurella multocida-Associated Diseases; 2.2 Major Virulence Factors of Pasteurella multocida; 2.2.1 LPS; 2.2.2 Capsule; 2.2.3 Adhesins; 2.2.4 Outer Membrane Proteins and Porins; 2.2.5 Pasteurella multocida Toxin; 2.2.6 Aspects of PMT in Osteoimmunology; 3…Discussion; Acknowledgments; References; 201 Molecular Biology of Pasteurella multocida Toxin; Abstract; 1…Structure of PMT; 2…Uptake into Eukaryotic Cells; 3…Activation of Heterotrimeric G Proteins; 4…Substrate Specificity; 5…G Protein Prerequisites for PMT Action; 5.1 Role of G beta gamma
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5.2 PMT-Induced Activation of G Proteins is Independent of GPCR Interaction6…PMT and Cytotoxic Necrotizing Factors; 7…Outlook; Acknowledgments; References; 219 Pasteurella multocida Toxin Interaction with Host Cells: Entry and Cellular Effects; Abstract; 1…Introduction; 2…PMT Structure and Function; 3…Cellular Uptake of PMT; 3.1 Binding to Host Cells; 3.2 Trafficking in Cells; 3.3 Translocation Across Cell Membranes; 4…Effects on Cell Signaling; 4.1 Cellular Responses; 4.2 Calcium Signaling; 4.3 Mitogenic Signaling; 4.4 Cytoskeletal Signaling; 4.5 cAMP Signaling; 4.6 Adipogenic Signaling
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4.7 Osteogenic Signaling
Additional Edition:
ISBN 9783642310164
Additional Edition:
Buchausg. u.d.T. Pasteurella multocida Berlin : Springer, 2012 ISBN 3642310168
Additional Edition:
ISBN 9783642310164
Language:
English
Subjects:
Medicine
Keywords:
Pasteurella multocida
;
Pathogenität
;
Aufsatzsammlung
DOI:
10.1007/978-3-642-31017-1
URL:
Volltext
(lizenzpflichtig)
Author information:
Aktories, Klaus 1948-
Author information:
Orth, Joachim Hans Christian 1974-
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