Format:
Online Ressource (625 pages)
Edition:
Online-Ausg.
ISBN:
9780124186859
,
0124186858
,
0124186793
,
9780124186798
,
1306154405
,
9781306154406
Content:
Drug use and its consequences / B. Madras -- Genetics of substance use, abuse, cessation, and addiction : novel data implicate copy number variants / Uhl et al. -- Epidemiology of drug abuse : building blocks for etiologic research / Weinberg et al. -- Detection of populations at risk or addicted : screening, brief, intervention, and referral to treatment (SBIRT) in clinical settings / L. Gentilello -- Cocaine : mechanism and effects in the human brain / Trifilieff et al. -- Stress, anxiety, and cocaine abuse / Craige et al. -- The neuropathology of drug abuse / Bittner et al. -- The pathology of methamphetamine use in the human brain / S. Kish -- The effects of alcohol on the human nervous system / K. Brady -- The nicotine hypothesis / Brasic -- Smoking effects in the human nervous system / Schuman-Olivier -- Cognitive effects of nicotine / Sofuoglu et al. -- Effects of cannabis and cannabinoids in the human nervous system / H. Kalant -- Cannabis, cannabinoids, and the association with psychosis / Radhakrishnan et al. -- Effects of MDMA on the human nervous system / McCann et al. -- Sedative hypnotics / Ciraulo et al. -- Hallucinogens / Chan, Mendelson -- Inhalants : addiction and toxic effects in humans / Bowen et al. -- Emerging designer drugs / Nichols et al
Content:
Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. The Effects of Drug Abuse on the Human Nervous System presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter offering a specific focus on nicotine, alcohol, marijuana, cocaine, methamphetamine, MDMA, sedative-hypnotics, and designer drugs. Other chapters provide a context for drug use, with overviews of use and consequences, epidemiology and risk factors, genetic
Note:
Description based on print version record
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Front Cover; The Effects of Drug Abuse on the Human Nervous System; Copyright; Contents; List of Contributors; Chapter One -Drug Use and Its Consequences; ?1. INTRODUCTION; ?2.1DRUGS AND CONSEQUENCES; ?3. CONCLUSIONS; REFERENCES; Chapter Two -Genetics of Substance Use, Abuse, Cessation, and Addiction: Novel Data Implicate Copy Number Variants; ?1. INTRODUCTION; ?2.1. WORKING HYPOTHESIS I: GENOMIC VARIANTS OF SEVERAL CLASSES AND DIFFERING FREQUENCIES CONTRIBUTE TO VULNERABILITY TO ADDICTI...
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?2.2. WORKING HYPOTHESIS II: GENOMIC VARIANTS THAT CONTRIBUTE TO VULNERABILITY TO ADDICTION AND ABILITY TO QUIT PROVIDE LARGELY ...?2.3. WORKING HYPOTHESIS III: MOST GENOMIC VARIANTS THAT CONTRIBUTE TO DEPENDENCE OR ABILITY TO QUIT EXERT EFFECTS OF SMALL SIZE...; ?2.4. WORKING HYPOTHESIS IV: THERE ARE ROBUST OVERALL GENETIC INFLUENCES ON VULNERABILITY TO DEPENDENCE, MANY SHARED ACROSS VULN...; ?3. CONCLUSIONS; REFERENCES; Chapter Three -Epidemiology of Drug Abuse: Building Blocks for Etiologic Research; ?1. INTRODUCTION; ?2.1. EPIDEMIOLOGY; ?2.2. ETIOLOGY; ?3. CONCLUSIONS; ACKNOWLEDGMENTS
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REFERENCESChapter Four - Detection of Populations At-Risk or Addicted: Screening, Brief Intervention, and Referral to Treatment (SBIRT) in Clinical Settings; ?1. INTRODUCTION; ?2.1. USE OF ALCOHOL; ?2.2. SUBSTANCE ABUSE; ?2.3. PREVENTION AND INTERVENTION; ?3. CONCLUSIONS; REFERENCES; Chapter Five -Cocaine: Mechanism and Effects in the Human Brain; ?1. INTRODUCTION; ?2.1. COCAINE USE IN HUMANS; ?2.2. IMAGING COCAINE ABUSE IN THE HUMAN BRAIN; ?2.3. IMAGING COCAINE: BEHAVIORAL CORRELATES; ?2.4. DOPAMINE TRANSMISSION IN STRIATAL SUBDIVISIONS; ?3. CONCLUSIONS; REFERENCES
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Chapter Six - Stress, Anxiety, and Cocaine Abuse?1. INTRODUCTION; ?2.1. NEUROTRANSMITTER SYSTEMS IN COCAINE WITHDRAWAL-INDUCED ANXIETY AND STRESS-INDUCED RELAPSE; ?2.2. SEROTONIN; ?2.3. CORTICOTROPIN RELEASING FACTOR; ?2.4. NOREPINEPHRINE; ?2.5. ENDOGENOUS OPIOIDS; ?2.6. OTHER NEUROPEPTIDES; ?3. CONCLUSIONS; REFERENCES; Chapter Seven -The Neuropathology of Drug Abuse; ?1. INTRODUCTION; ?2.1. NEUROBIOLOGICAL BASICS OF DRUG ABUSE; ?2.2. CNS ALTERATIONS OF THE MAJOR DRUGS OF ABUSE; ?2.3. OPIOIDS AND DERIVATIVES; ?2.4. COCAINE; ?2.5. AMPHETAMINES, METHAMPHETAMINE, AND DESIGNER DRUGS
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?2.6. AMPHETAMINE AND METHAMPHETAMINE DERIVATIVES?2.7. NEUROPATHOLOGICAL INVESTIGATIONS OF (POLY-) DRUG ABUSERS; ?2.8. NEURODEGENERATION AND DRUGS OF ABUSE; ?3. CONCLUSIONS; REFERENCES; Chapter Eight -The Pathology of Methamphetamine Use in the Human Brain; ?1. INTRODUCTION; ?2.1. DOES METHAMPHETAMINE, A DOPAMINE RELEASER, CAUSE LOSS OF DOPAMINE NEURONAL MARKERS IN HUMAN BRAIN AS OBSERVED IN ANIMAL ST...; ?2.2. NONDOPAMINERGIC CHANGES IN BRAIN OF METHAMPHETAMINE USERS; ?2.3. DOES METHAMPHETAMINE CAUSE OXIDATIVE STRESS IN HUMAN BRAIN?
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?2.4. DOES METHAMPHETAMINE CAUSE GLIOSIS (ACTIVATED MICROGLIOSIS AND REACTIVE ASTROGLIOSIS), A REPUTED INDEX OF NEUROTOXICITY, I...
Additional Edition:
ISBN 9780124186798
Additional Edition:
Erscheint auch als Druck-Ausgabe Effects of drug abuse on the human nervous system Amsterdam : Elsevier, 2014
Language:
English
Keywords:
Electronic books
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