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  • 1
    Book
    Book
    Totowa, NJ : Humana Press
    UID:
    gbv_566650215
    Format: XI, 277 S. , Ill., graph. Darst. , 24cm
    ISBN: 1588296385 , 9781588296382
    Series Statement: Methods in molecular biology 460
    Note: Toxicogenomics and classical toxicology : how to improve prediction and mechanistic understanding of human toxicity / Donna L. MendrickUse of traditional endpoints and gene dysregulation to understand mechanisms of toxicity : Toxicogenomics in mechanistic toxicoogy / Wayne R. Buck, Jeffrey F. Waring, Eric A. Blomme -- Quality control of microarray assays for toxicogenomic and in vitro diagnostic applications / Karol L. Thompson and Joseph Hackett -- Role of statistics in toxicogenomics / Michael Elashoff -- Predictive toxicogenomics in preclinical discovery / Scott A. Barros and Rory B. Martin -- In vivo predictive toxicogenomics / Mark W. Porter -- Bioinformatics : databasing and gene annotation / Lyle D. Burgoon and Timothy R. Zacharewski -- Microarray probe mapping and annotation in cross - species comparative toxicogenomics / John N Calley, William B Mattes, Timothy P. Ryan -- Toxicogenomics in biomarker discovery -- Marc F. DeCristofaro, Kellye K. Daniels -- From pharmacogenomics to translational biomarkers / Donna L. Mendrick -- Public consortium efforts in toxicogenomics / William B. Mattes -- Applications of toxicogenomics to nonclinical drug development / Frank D. Sistare, Joseph J. DeGeorge. , Toxicogenomics and classical toxicology : how to improve prediction and mechanistic understanding of human toxicity / Donna L. Mendrick -- Use of traditional endpoints and gene dysregulation to understand mechanisms of toxicity : Toxicogenomics in mechanistic toxicoogy / Wayne R. Buck, Jeffrey F. Waring, Eric A. Blomme -- Quality control of microarray assays for toxicogenomic and in vitro diagnostic applications / Karol L. Thompson and Joseph Hackett -- Role of statistics in toxicogenomics / Michael Elashoff -- Predictive toxicogenomics in preclinical discovery / Scott A. Barros and Rory B. Martin -- In vivo predictive toxicogenomics / Mark W. Porter -- Bioinformatics : databasing and gene annotation / Lyle D. Burgoon and Timothy R. Zacharewski -- Microarray probe mapping and annotation in cross - species comparative toxicogenomics / John N Calley, William B Mattes, Timothy P. Ryan -- Toxicogenomics in biomarker discovery -- Marc F. DeCristofaro, Kellye K. Daniels -- From pharmacogenomics to translational biomarkers / Donna L. Mendrick -- Public consortium efforts in toxicogenomics / William B. Mattes -- Applications of toxicogenomics to nonclinical drug development / Frank D. Sistare, Joseph J. DeGeorge
    Additional Edition: ISBN 9781603270489
    Additional Edition: Erscheint auch als Online-Ausgabe Mendrick, Donna L. Essential Concepts in Toxicogenomics Totowa, NJ : Humana Press, 2008 ISBN 9781603270489
    Language: English
    Subjects: Medicine
    RVK:
    RVK:
    Keywords: Toxikologie ; Genomik ; Gentoxikologie ; Aufsatzsammlung ; Aufsatzsammlung ; Aufsatzsammlung
    URL: Cover
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Online Resource
    Online Resource
    Totowa, NJ :Humana Press :
    UID:
    edocfu_9959000177402883
    Format: 1 online resource (XI, 277 p.)
    Edition: 1st ed. 2008.
    ISBN: 1-60327-048-5
    Series Statement: Methods in Molecular Biology, 460
    Content: The field of toxicogenomics has been growing quickly, yet with rapid growth comes the need to periodically reflect on the nature of the field. Essential Concepts in Toxicogenomics collects reviews, opinion pieces and case studies from the leading experts in this dynamic field with a focus on its application to pharmaceuticals. Topics covered include issues that affect the quality of toxicogenomics experiments, statistical approaches to their data analysis, the use of such data to build toxicogenomic models, and the utilization of genomics to identify biomarkers within the preclinical and clinical arenas. Although not in the standard Methods in Molecular Biology™ series format, this volume retains the practicality and usefulness of the highly successful series. Informative and cutting-edge, Essential Concepts in Toxicogenomics is an ideal resource for pharmaceutical companies, chemical manufacturers, toxicologists, and all who must keep up-to-date on progress in this vital and important field.
    Note: Bibliographic Level Mode of Issuance: Monograph , Toxicogenomics and Classic Toxicology: How to Improve Prediction and Mechanistic Understanding of Human Toxicity -- Use of Traditional End Points and Gene Dysregulation to Understand Mechanisms of Toxicity: Toxicogenomics in Mechanistic Toxicology -- Quality Control of Microarray Assays for Toxicogenomic and In Vitro Diagnostic Applications -- Role of Statistics in Toxicogenomics -- Predictive Toxicogenomics in Preclinical Discovery -- In Vivo Predictive Toxicogenomics -- Bioinformatics: Databasing and Gene Annotation -- Microarray Probe Mapping and Annotation in Cross-Species Comparative Toxicogenomics -- Toxicogenomics in Biomarker Discovery -- From Pharmacogenomics to Translational Biomarkers -- Public Consortium Efforts in Toxicogenomics -- Applications of Toxicogenomics to Nonclinical Drug Development: Regulatory Science Considerations. , English
    Additional Edition: ISBN 1-58829-638-5
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 3
    Online Resource
    Online Resource
    Totowa, NJ :Humana Press :
    UID:
    edoccha_9959000177402883
    Format: 1 online resource (XI, 277 p.)
    Edition: 1st ed. 2008.
    ISBN: 1-60327-048-5
    Series Statement: Methods in Molecular Biology, 460
    Content: The field of toxicogenomics has been growing quickly, yet with rapid growth comes the need to periodically reflect on the nature of the field. Essential Concepts in Toxicogenomics collects reviews, opinion pieces and case studies from the leading experts in this dynamic field with a focus on its application to pharmaceuticals. Topics covered include issues that affect the quality of toxicogenomics experiments, statistical approaches to their data analysis, the use of such data to build toxicogenomic models, and the utilization of genomics to identify biomarkers within the preclinical and clinical arenas. Although not in the standard Methods in Molecular Biology™ series format, this volume retains the practicality and usefulness of the highly successful series. Informative and cutting-edge, Essential Concepts in Toxicogenomics is an ideal resource for pharmaceutical companies, chemical manufacturers, toxicologists, and all who must keep up-to-date on progress in this vital and important field.
    Note: Bibliographic Level Mode of Issuance: Monograph , Toxicogenomics and Classic Toxicology: How to Improve Prediction and Mechanistic Understanding of Human Toxicity -- Use of Traditional End Points and Gene Dysregulation to Understand Mechanisms of Toxicity: Toxicogenomics in Mechanistic Toxicology -- Quality Control of Microarray Assays for Toxicogenomic and In Vitro Diagnostic Applications -- Role of Statistics in Toxicogenomics -- Predictive Toxicogenomics in Preclinical Discovery -- In Vivo Predictive Toxicogenomics -- Bioinformatics: Databasing and Gene Annotation -- Microarray Probe Mapping and Annotation in Cross-Species Comparative Toxicogenomics -- Toxicogenomics in Biomarker Discovery -- From Pharmacogenomics to Translational Biomarkers -- Public Consortium Efforts in Toxicogenomics -- Applications of Toxicogenomics to Nonclinical Drug Development: Regulatory Science Considerations. , English
    Additional Edition: ISBN 1-58829-638-5
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Online Resource
    Online Resource
    Totowa, NJ :Humana Press :
    UID:
    almahu_9949251555902882
    Format: 1 online resource (XI, 277 p.)
    Edition: 1st ed. 2008.
    ISBN: 1-60327-048-5
    Series Statement: Methods in Molecular Biology, 460
    Content: The field of toxicogenomics has been growing quickly, yet with rapid growth comes the need to periodically reflect on the nature of the field. Essential Concepts in Toxicogenomics collects reviews, opinion pieces and case studies from the leading experts in this dynamic field with a focus on its application to pharmaceuticals. Topics covered include issues that affect the quality of toxicogenomics experiments, statistical approaches to their data analysis, the use of such data to build toxicogenomic models, and the utilization of genomics to identify biomarkers within the preclinical and clinical arenas. Although not in the standard Methods in Molecular Biology™ series format, this volume retains the practicality and usefulness of the highly successful series. Informative and cutting-edge, Essential Concepts in Toxicogenomics is an ideal resource for pharmaceutical companies, chemical manufacturers, toxicologists, and all who must keep up-to-date on progress in this vital and important field.
    Note: Bibliographic Level Mode of Issuance: Monograph , Toxicogenomics and Classic Toxicology: How to Improve Prediction and Mechanistic Understanding of Human Toxicity -- Use of Traditional End Points and Gene Dysregulation to Understand Mechanisms of Toxicity: Toxicogenomics in Mechanistic Toxicology -- Quality Control of Microarray Assays for Toxicogenomic and In Vitro Diagnostic Applications -- Role of Statistics in Toxicogenomics -- Predictive Toxicogenomics in Preclinical Discovery -- In Vivo Predictive Toxicogenomics -- Bioinformatics: Databasing and Gene Annotation -- Microarray Probe Mapping and Annotation in Cross-Species Comparative Toxicogenomics -- Toxicogenomics in Biomarker Discovery -- From Pharmacogenomics to Translational Biomarkers -- Public Consortium Efforts in Toxicogenomics -- Applications of Toxicogenomics to Nonclinical Drug Development: Regulatory Science Considerations. , English
    Additional Edition: ISBN 1-58829-638-5
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
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