In:
Pediatric Dermatology, Wiley, Vol. 20, No. 2 ( 2003-03), p. 103-107
Abstract:
Abstract: Among 27 pediatric patients with a clinicopathologic diagnosis of discoid lupus erythematosus (DLE), 15 had localized cutaneous lesions and 12 had disseminated lesions. During a mean follow‐up period of 36 months, seven patients (26%) developed systemic lupus erythematosus (SLE). Four of these patients were less than 10 years of age. No correlation was found between localized and disseminated lesions and evolution to SLE. Three of four patients with a positive family history for rheumatoid disease developed SLE (p 〈 0.05). Hyperpigmentation was significantly more frequent (p 〈 0.04) in children less than 10 years of age. There was a female predominance of 5:1 among patients less than 10 years of age. Our findings suggest that onset of DLE prior to 10 years of age does not indicate a greater risk of developing SLE. The occurrence of localized or disseminated lesions does not seem to influence the outcome.
Type of Medium:
Online Resource
ISSN:
0736-8046
,
1525-1470
DOI:
10.1046/j.1525-1470.2003.20201.x
Language:
English
Publisher:
Wiley
Publication Date:
2003
detail.hit.zdb_id:
2020833-9
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