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Format: 1 Online-Ressource (256 Seiten).

Edition: Originalausgabe

ISBN: 978-3-8379-7761-5

Series Statement: Forschung psychosozial

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8379-3051-1

Language: German

Subjects: Education

Keywords: Kognitive Störung ; Interpersonale Kommunikation ; Kommunikationshilfe

DOI: 10.30820/9783837977615

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Author information: Erdin, Gisela 1955-

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Format: 1 Online-Ressource (xviii, 362 Seiten) : , Illustrationen.

ISBN: 978-90-47-43330-9

Series Statement: The judges Volume 5

Note: Includes bibliographical references and index. - Human rights and international law -- Non-qualified rights -- Right to liberty and security -- The notion of fair trial and its implications -- Private and family life -- Freedom of expression -- Non-discri+mination -- Other issues

Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-90-04-16628-8

Language: English

Subjects: Law

DOI: 10.1163/ej.9789004166288.i-363

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Author information: Spielmann, Dean, 1962-

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Format: 1 online resource (136 pages)

Edition: 1st ed.

ISBN: 9789811324475

Note: Intro -- Contents -- Zebrafish, Danio Rerio as a Replacement Alternative Model Useful in CKDu Experiments -- Abstract -- Introduction -- The Concept of Replacement Alternative -- Scientific Importance of Zebrafish (Danio Rerio) -- Scientific Attributes of Zebrafish -- Introduction of Zebrafish Model to Sri Lanka -- Materials and Methods -- Comprehensive Training on Zebrafish Model -- Results -- Discussion and Conclusion -- Scientific Applicability of Zebrafish Model in the Sri Lankan Context -- Acknowledgments -- References -- Testing Method Development and Validation for in Vitro Skin Irritation Testing (SIT) by Using Reconstructed Human Epidermis (RhE) Skin Equivalent - EPiTRI® -- Abstract -- Introduction -- Materials and Methods -- EPiTRI® Reconstructed Human Epidermis -- Selection of Test Substances -- Cell Viability Measurement by MTT Reduction -- In Vitro Skin Irritation Test (SIT) -- Prediction Model -- Statistical Analysis -- Results and Discussions -- Change of TER and Structural Morphology during the Reconstruction of EPiTRI® -- Quality Control of EPiTRI® -- Protocol Refinements for the Skin Irritation Test of EPiTRI® -- Modification of Washing Method for SIT -- Chemical Exposure Time -- Pre-incubation Time and Post-incubation Volume -- Conclusion -- References -- Development the Technique for the Preparation and Characterization of Reconstructed Human Epidermis (RHE) -- Abstract -- Back Ground -- Structure of Skin Networks -- Epidermis -- Dermis -- Keratinocytes Cells -- Melanocytes Cell -- Fibroblasts Cell -- Reconstruct Ed Human Epiderm is (Rhe) -- Skin Irritation Test -- Examination of Histology Network with Hematoxyline - Eosin Determination -- Immunohistochemical (IHC) -- Result and Discussion -- Cell Culture of Keratinocytes, Melanocytes and Fibroblasts -- Making of Feeder Layer (Dermis Eqivalen). , Making of RHE Tissue (Reconstructed Human Epidermis) -- Measuring of Cell Life Using MTT Method -- Making Histology Preparations of Reconstructed Human Epiderm Using Staining of Hematoxylin-Eosin (HE) -- Immunohistochemical (IHC) Examination of RHE Skin Tissue Using Cytokeratin 10 Antibody Marker -- Conclusion -- References -- Alternative Research (3Rs) in the World, Asia and Japan -- The World -- Asia -- Japan -- References -- Approaches to Reducing Animal Use for Acute Toxicity Testing: Retrospective Analyses of Pesticide Data -- Abstract -- Introduction -- Materials and Methods -- Data Quality Evaluation -- Categorization of Data -- Analyses -- Results -- Distribution of Substances Among Hazard Categories -- EPA Hazard Categories -- GHS Hazard Categories -- Concordance of Oral and Dermal Hazard Classifications -- Discussion -- Disclaimer -- Acknowledgements -- References -- Progress in Eliminating One-Year Dog Studies for the Safety Assessment of Pesticides -- Abstract -- Introduction and Objective -- Review of Regulatory Data not in the Public Domain -- Results of the Studies Conducted in Germany -- Results of the Studies Conducted by the US EPA -- Relevance of the One-Year Dog Study in Assessing Human Health Risks for Registration of Pesticides. An Update to Include Pesticides Registered in Japan -- Discussion -- References -- Cosmetic Regulation and Alternatives to Animal Experimentation in India -- Abstract -- Introduction -- History of Ban of Animal Testing of Cosmetics in EU -- Cosmetic Regulation in India -- Ban on Use of Animals in Cosmetic Testing -- Prohibition of Import of Cosmetics Tested on Animals -- Conclusion -- Acknowledgments -- References -- Guidance on the Use of Alternative Test Methods for the Safety Assessment of Cosmetics and Quasi-drugs -- Abstract -- MHLW Updates -- JaCVAM Update. , Guidance for Alternative to Animal Testing -- References -- Alternatives and Refinement for Animal Experimentation in Cancer Research -- Abstract -- Introduction -- Alternatives in Cancer Research -- 3R's -- CPCSEA -- Refinement in Cancer Research -- Conclusion -- References -- 3Rs in Quality Control of Human Vaccines: Opportunities and Barriers -- Abstract -- Animal Use in Vaccine Quality Control -- 3Rs History and Vaccine Context -- 3Rs Successes -- Barriers to 3Rs -- Perspectives for the Future -- Concluding Remarks -- References -- The Use of Adverse Outcome Pathways (AOPs) to Support Chemical Safety Decisions Within the Context of Integrated Approaches to Testing and Assessment (IATA) -- Abstract -- Introduction -- The Adverse Outcome Pathway (AOP) Framework -- The Use of AOPs to Support Hazard and Risk Assessment -- AOP-Supported IATA Case Study: Skin Sensitization -- Summary -- References -- Mechanism-Based Evaluation System for Hepato- and Nephrotoxicity or Carcinogenicity Using Omics Technology -- Abstract -- Introduction -- Chemicals, Animal Test and Microarray Analysis -- AOP-Based Mechanism of Hepatotoxicity Suggested by Case Study with Carbon Tetrachloride -- AOP-Based Mechanism of Nephrotoxicity Suggested by Case Study with Cisplatin -- Detection System for Hepato- and Nephrotoxicity -- Prediction System for Hepatic and Renal Carcinogenicity: CARCINOscreen® -- Concluding Remarks -- Acknowledgement -- References -- Alternative Methods for Developmental Toxicity Testing Using Mouse ESCs -- Abstract -- Introduction -- Materials and Methods -- Results -- Discussion -- Acknowledgement -- References -- Futuristic Approach to Alternative Model Organisms: Hydra Stakes Its Claim -- Abstract -- Introduction -- Hydra-Systematics -- Physiology and Anatomy -- Reproduction -- Regeneration -- End Point Analysis. , Morphological Observation in Hydra Following Exposure to Chemicals -- Methodology -- Impact of Chemicals on Hydra Growth Rate -- Methodology -- Impact of Chemicals on Hydra's Regeneration Ability -- Methodology -- Impact of Chemicals on Hydra Cell Cycle -- Methodology -- Assessment of Cell Death in Hydra by ROS Generation and Apoptosis -- Determination of ROS Generation in Hydra by H2-DCFDA Staining -- Determination of Apoptosis by Acridine Orange and DAPI Staining -- Acridine Orange Staining -- 4′-6-Diamidino-2-Phenylindole (DAPI) Staining -- Genotoxicity Assessment in Hydra Following Chemical Exposure -- Methodology -- Transcriptional Alterations in Hydra Following Chemicals Exposure -- Conclusion -- Acknowledgments -- References -- The Lush Prize and Young Researcher Asia Awards 2016 -- Abstract -- Introduction -- The Lush Prize Categories -- The Black Box Prize -- The Lush Prize Is a '1R' Initiative -- Launch of Lush Prize 'Young Researcher Asia' Awards in 2016 -- Projects Funded by the Lush Prize to Date -- References -- Author Index.

Additional Edition: Print version: Kojima, Hajime Alternatives to Animal Testing Singapore : Springer Singapore Pte. Limited,c2018 ISBN 9789811324468

Language: English

Keywords: Electronic books.

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Format: 1 online resource (304 pages) : , illustrations

Additional Edition: Print version: Spielmann, Raj. Wahrscheinlichkeitsrechnung und Statistik : Mathematische Anwendungen in Natur und Gesellschaft. Berlin, [Germany] ; Boston, [Massachusetts] : De Gruyter, c2017 ISBN 9783110542523

Language: German

Subjects: Mathematics

Keywords: Electronic books.

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Format: 1 Online-Ressource (336 Seiten)

Edition: 1. Aufl.

ISBN: 9783666451904 , 9783525451908

Content: ***Angaben zur beteiligten Person Zitterbarth: Dr. Walter Zitterbarth, Diplom-Psychologe, ist TZI-Lehrbeauftragter, systemischer Lehrtherapeut und Hochschullehrer in Marburg.

Content: ***Angaben zur beteiligten Person Spielmann: Dr. Jochen Spielmann, Kunstwissenschaftler, ist TZI-Lehrbeauftragter, Erwachsenenpädagoge und Supervisor in Berlin.

Content: ***Angaben zur beteiligten Person Schneider-Landolf: Mina Schneider-Landolf, Diplom-Psychologin, ist TZI-Lehrbeauftragte, Psychotherapeutin und Supervisorin in Berlin.

Content: ***Angaben zur beteiligten Person Lotz: Dr. Walter Lotz war Professor für Soziale Arbeit und TZI-Lehrbeauftragter.

Content: ***Angaben zur beteiligten Person Trost: Prof. Dr. med. Alexander Trost, Facharzt für Kinder- und Jugendpsychiatrie und Psychotherapie, Facharzt für Psychosomatische Medizin, systemischer Familientherapeut (DGSF-Lehrtherapeut) und Supervisor (DGSF), TZI-Lehrbeauftragter (RCI) und NLP-Master-Practitioner, ist in eigener Praxis, als Dozent und Autor tätig.

Content: ***Angaben zur beteiligten Person von Kanitz: Anja von Kanitz ist geschäftsführende Redakteurin der TZI-Fachzeitschrift und tätig in Personal- und Organisationsentwicklung.

Content: In the 40 years since Ruth C. Cohn developed theme-centered interaction (TCI), it has grown from an educational-therapeutic model to a comprehensive concept aimed at addressing personality development and group leadership. TCI allows the learning and working processes of individuals, groups, teams and organizations to be reflected on, controlled, and managed. Processes of life-work balance can also be coordinated with TCI and empowerment furthered. Today, TCI is successfully being employed in adult education, schools, businesses, counseling and pastoring settings, manager development and training, and in many other areas. This volume contains 53 short contributions highlighting the central concepts of TCI, their origin, and further development. It thus provides a state-of-the-art look at this concept in a clear, systematic, and scientifically sound manner. This handbook represents at once a theoretical treatise, a textbook for anyone desiring information about TCI, for persons presently undergoing TCI training, who are teaching TCI, applying it or doing scientific research on this subject. A uniform structure in most texts enables the reader to quickly and efficiently compare different subjects.

Additional Edition: ISBN 9783666451904

Language: English

DOI: 10.13109/9783666451904

URL: Volltext

Author information: Zitterbarth, Walter,

Author information: Schneider-Landolf, Mina,