Format:
Online-Ressource (400 p)
,
77 b&w, ill
Edition:
RSC eBook Collection 1968-2009
ISBN:
1847557961
,
9781847557964
Series Statement:
RSC biomolecular sciences [8]
Content:
This insightful book spotlights both the structural and medicinal chemistry aspects of drug design, Computational methods impact all aspects of modern drug discovery and most notably these methods move rapidly from academic exercises to becoming drugs in clinical trials! This insightful book represents the experience and understanding of the global experts in the field and spotlights both the structural and medicinal chemistry aspects of drug design. The need to 'encode' the factors that determine adsorption, distribution, metabolism, excretion and toxicology are explored, as they remain the critical issues in this area of research. This indispensable resource provides the reader with: * A rich understanding of modern approaches to docking * A comparison and critical evaluation of state-of-the-art methods * Details on harnessing computational methods for both analysis and prediction * An insight into prediction potencies and protocols for unbiased evaluations of docking and scoring algorithms * Critical reviews of current fragment based methods with perceptive applications to kinases Addressing a wide range of uses of protein structures for drug discovery the Editors have created and essential reference for professionals in the pharmaceutical industry and moreover an indispensable core text for all graduate level courses covering molecular interactions and drug discovery
Note:
Ebook
,
9780854043651_Publicity; i_iv; v_ix; x_xviii; 001_023; 024_046; 047_072; 073_094; 095_110; 111_126; 127_134; 135_154; 155_180; 181_191; 192_204; 205_222; 223_241; 242_267; 268_290; 291_318; 319_348; 349_365; 366_382
Additional Edition:
Erscheint auch als Druck-Ausgabe Computational and Structural Approaches to Drug Discovery Ligand-Protein Interactions
Language:
English
Subjects:
Chemistry/Pharmacy
Keywords:
Arzneimitteldesign
;
Ligand
;
Proteindesign
;
Arzneimittelentwicklung
;
Ligand
;
Proteindesign
;
Electronic books
URL:
Volltext
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