Format:
Online-Ressource (X, 344 p. 24 illus., 3 illus. in color, digital)
ISBN:
9783642354250
Series Statement:
Current Topics in Behavioral Neurosciences 14
Content:
The book highlights important new research using current state-of-the-art approaches by prominent researchers in the field of depression. A broad range of topics is covered, beginning with a description of the phenotypic features of clinical depression, followed by chapters on the cellular and molecular basis, functional neuroimaging correlates and information-processing accounts. Finally, existing and novel treatment approaches are covered. In this way the volume brings together the key disciplines involved in the neurobiological understanding of depression to provide an update of the field and outlook to the future. Together, the volume chapters provide focused and critical reviews that span a broad range of topics suitable for both students and established investigators interested in the present state of depression research
Content:
The book highlights important new research using current state-of-the-art approaches by prominent researchers in the field of depression. A broad range of topics is covered, beginning with a description of the phenotypic features of clinical depression, followed by chapters on the cellular and molecular basis, functional neuroimaging correlates and information-processing accounts. Finally, existing and novel treatment approaches are covered. In this way the volume brings together the key disciplines involved in the neurobiological understanding of depression to provide an update of the field and outlook to the future. Together, the volume chapters provide focused and critical reviews that span a broad range of topics suitable for both students and established investigators interested in the present state of depression research
Note:
Includes index
,
Behavioral Neurobiology of Depressionand Its Trea tment; Preface; Contents; Part I Phenotypic Features; 218 Classification of Depressive Disorders; Abstract; 1…''Clinical'' Depression; 2…Clinical Symptoms of Depression; 3…Some Distinctions in Acute Clinical Presentation; 3.1 Melancholic Depression; 3.2 Psychotic Depression; 3.3 Atypical Depression; 4…Distinctions in Depressive Course; 4.1 Recurrent Versus Single Episodes of Depression; 4.2 Bipolar Versus Unipolar Illness; 4.3 Seasonal Affective Disorder; 4.4 Brief Recurrent Depression; 5…Milder Depressive Disorders
,
6…Classification in ICD-10 and DSM-IV7…Implications and Limitations of Classification of Depression; References; 214 Developmental Aspects of Mood Disorders; Abstract; 1…Changes in the Social World; 2…Genetic Innovation Across Development; 3…Continuing Maturation of the Emotional Brain; 4…Developmental Aspects of Information-Processing Biases; 5…Concluding Remarks; References; 221 Animal Models of Depression Vulnerability; Abstract; 1…Introduction; 2…What is Vulnerability to Depression?; 3…How Do We Define Animal Models of Depression Vulnerability?; 4…The Diathesis--Stress Concept
,
5…How Do We Learn Whether Vulnerability Is Truly Vulnerability?6…A Note on Genetic Models and the Diathesis--Stress Concept; 7…Adverse Early Life Events; 7.1 Maternal Separation; 7.2 Prenatal Stress; 8…Stressful Life Events During Adulthood; 8.1 Acute Stress; 8.2 Chronic Stress; 9…Personality as a Vulnerability Factor; 10…Vulnerability Based on Post hoc Assessment; 11…The Sex/Gender Factor; 12…Limitations and Caveats; Acknowledgments; References; 224 Genetic Mouse Models of Depression; Abstract; 1…Introduction; 2…Depressed Mice?; 2.1 Depressed Mood; 2.1.1 The Forced Swim TestForced Swim Test
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2.1.2 The Tail Suspension TestTail Suspension Test2.2 Anhedonia; 2.3 AnxietyAnxiety; 2.4 Other Symptoms; 3…Genetic Mouse Models of Depression; 3.1 5-HT Transporter5-HT Transporter; 3.2 Noradrenaline; 3.2.1 Adrenoceptors; 3.2.2 Noradrenaline Transporter; 3.3 CRFCRF'' \t ''See Corticotrophin-Releasing Factor-Related Models; 3.4 BDNFBDNF'' \t ''See Brain-Derived Neurotrophic Factor; 4…Concerns and Considerations; 4.1 Background Strain; 4.2 Sex Effects; 4.3 Environmental Factors; 4.4 The Perfect Model?; Acknowledgments; References; Part II Cellular and Molecular Basis
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225 The Genetic Basis of DepressionAbstract; 1…Identifying the Role of Genetics in the Aetiology of Depression; 1.1 Quantitative Genetic Studies of DepressionQuantitative genetics; 1.2 The Genetic Relationship Between Depression and Other Disorders; 2…Identifying Which Genes are Associated with Depression; 2.1 Molecular Genetic Methods: LinkageLinkage; 2.2 Molecular Genetic Methods: Candidate Gene AssociationsCandidate genes; 2.3 Molecular Genetic Methods: Genome-Wide Association; 3…Developing Technologies; 3.1 Copy Number VariantsCopy Number Variants; 3.2 Next Generation Sequencingsequencing
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4…Interactions
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Preface -- Part 1. Phenotypic features.- Classification of mood disorders. Developmental aspects of depression. Animal models of depression vulnerability. Genetic mouse models of depression.- Part 2. Cellular and Molecular Basis -- The Genetic basis of depression. Neurochemical Imaging and Depressive Behaviours. Inflammation and Depression. Major Depression: A Role for Hippocampal Neurogenesis? Neurobiological Markers of Familial Risk for Depression.- Part 3. Cognitive accounts.- Emotional Processing and Antidepressant Action. What Can Fear and Reward Learning Teach Us About Depression? The Use of Cognitive Bias Modification and Imagery in the Understanding and Treatment of Depression.- Part 4. Treatment.- Pharmacological Treatment of Unipolar Depression. New Approaches in the Treatment of Bipolar Depression. Molecular and Cellular Mechanisms of Antidepressant Action. Neurosurgical treatments of depression - clinical and preclinical studies.
Additional Edition:
9783642354243
Additional Edition:
Buchausg. u.d.T. Behavioral neurobiology of depression and its treatment Berlin : Springer, 2013 9783642354243
Language:
English
Subjects:
Psychology
Keywords:
Depression
;
Neurobiologie
;
Verhalten
;
Aufsatzsammlung
DOI:
10.1007/978-3-642-35425-0
URL:
Volltext
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