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  • BSZ  (208)
Type of Material
Type of Publication
Consortium
  • BSZ  (208)
  • GBV  (132)
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  • 1
    UID:
    (DE-627)1725102579
    ISBN: 9782807607323
    In: Inha-Taehakkyo (3. : 2017 : Incheon), On the Asian and European origins of legal and political systems, Bern : P.I.E. Peter Lang, 2018, (2018), Seite 265-274, 9782807607323
    In: year:2018
    In: pages:265-274
    Language: English
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  • 2
    UID:
    (DE-627)1738103625
    ISBN: 0190278358
    In: Old society, new belief, New York, NY : Oxford University Press, 2017, (2017), Seite 69-80, 0190278358
    In: 9780190278359
    In: year:2017
    In: pages:69-80
    Language: English
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  • 3
    Online Resource
    Online Resource
    Cambridge : Cambridge University Press
    UID:
    (DE-627)746776578
    Format: Online-Ressource (348 p.)
    Edition: Online-Ausg. 2013 Electronic reproduction; Available via World Wide Web
    ISBN: 9781107009066 , 9781107057593
    Content: A comparative and interdisciplinary study arguing for a more sophisticated appreciation of the rise of the Hunnic Empire
    Note: Description based upon print version of record , Cover; Contents; Maps; Acknowledgements; Chapter 1 Introduction; Steppe empires and their significance in the history of wider Eurasia and Late Imperial Rome; The Huns, a new world order and the birth of 'Europe'; Chapter 2 Rome's Inner Asian enemies before the Huns; The Parthian Empire; The Partho-Sassanian confederacy; Chapter 3 The Huns in Central Asia; Inner Asian empires before the fourth century ad; Introduction; The Xiongnu, the Scythians and the Sarmatians; The Hun-Xiongnu connection; The Yuezhi (Kushans), Kangju and the Wusun , Contemporary Inner Asian empires (fourth, fifth and sixth centuries ad)The White Huns (Chionites, Kidarites and Hephtalites); The Rouran Khaganate; Sedentarism among steppe peoples; Chapter 4 The Huns in Europe; The Hunnic Empire, the Germanic tribes and Rome; The impact of the Hunnic Empire and Roman military collapse; The Battle of Chalons, the salvation of Western Civilization?; Roman military impotence post AD 451; Chapter 5 The end of the Hunnic Empire in the west; Civil war and the rise of Ardaric; Ardaric and the Gepids , Odoacer the king of the Torcilingians, Rogians, Scirians and the HerulsValamer the king of the Huns and founding king of the Ostrogoths; Orestes the royal secretary; New invasions from the east; The dissolution of the Hunnic state: an analysis; Chapter 6 The later Huns and the birth of Europe; The later Hunnic Empire of the Bulgars, Oghurs and Avars; The birth of a new Europe; Conclusion; Notes; Chapter 1: introduction; Chapter 2: rome's inner asian enemies before the huns; Chapter 3: the huns in central asia; Chapter 4: the huns in europe; Chapter 5: the end of the hunnic empire in the west , Chapter 6: the later huns and the birth of europeConclusion; Bibliography; Index , Electronic reproduction; Available via World Wide Web
    Additional Edition: 9781107058842
    Additional Edition: 9781107009066
    Additional Edition: Print version The Huns, Rome and the Birth of Europe
    Language: English
    Keywords: Electronic books
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  • 4
    E-Resource
    E-Resource
    Osnabrück : Epos
    UID:
    (DE-627)1600962394
    Format: 1 CD-ROM , 12 cm
    ISBN: 9783940255204
    Language: German
    Keywords: Performance ; Interaktion ; Embodiment ; CD-ROM
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  • 5
    Online Resource
    Online Resource
    [Erscheinungsort nicht ermittelbar] : Biovetenskaper och näringslära / Biosciences and Nutrition
    UID:
    (DE-627)1803215356
    Content: In our characterization of mouse strains carrying mutations in nuclear receptor and aromatase genes we have found phenotypes which resemble four human diseases: benign prostatic hyperplasia (BPH), Sjögren s syndrome (SS), amyotrophic lateral sclerosis (ALS), and exocrine pancreatic insufficiency. The work in this thesis was designed to understand the roles of LXRalpha, LXRbeta and aromatase in development of these diseases and to investigate whether these animal models help us (1) to understand the etiology of the corresponding human diseases and (2) to develop new therapeutic approaches for the treatment of these diseases. Paper I: Male LXRbeta-/- mice develop motor neuron disease with age. Because the LXR ligand, beta-sitosterol, has been implicated in ALS, we examined the possibility that LXRbeta-/- mice were more susceptible than their wild type (WT) littermates to the toxic effects of beta-sitosterol. Three weeks of beta-sitosterol treatment of 8-month-old LXRbeta-/- male mice resulted in ALS-Parkinson s like syndrome, characterized by death of the tyrosine hydroxylase-positive dopaminergic neurons in the brain and death of large motor neurons in the spinal cord. WT mice were not affected by beta-sitosterol. In LXRbeta-/- mice, there was activation of microglia and accumulation of intracellular protein aggregates in motor neurons, abnormalities which have been observed in ALS patients. The level of 24-hydroxycholesterol, the main excretory metabolite of cholesterol synthesized in the brain, was increased upon beta-sitosterol treatment in mutant but not in WT mice. Thus loss of LXRbeta renders mice more susceptible to the neurotoxic effects of beta-sitosterol and we suggest that, in human populations where the incidence of ALS is unusually high, there may be genetic alterations in LXRbeta gene signaling pathways. Paper II: In this study we found that as LXRalpha-/- mice age, they develop smooth-muscle actin-positive stromal overgrowth around the ducts of the ventral prostate (VP) and numerous fibrous nodules growing into the ducts and causing obstruction and extreme dilatation of the ducts. We investigated whether the stromal hyperplasia in LXRalpha-/- mice could help in understanding the etiology of human BPH. We found proliferation in the epithelial cells but not in the accumulated stromal cells in the VP of LXRalpha-/- mice. Expression of the transcription repressor of E-cadherin, Snail and the intracellular mediator of TGF-beta, Smad 2/3, was increased. We postulate that loss of LXRalpha from the prostatic epithelium results in increased epithelial proliferation and epithelial to mesenchymal transition, resulting in excessive stromal accumulation. These findings suggest that LXRalpha-/- mice may be a useful model to study prostatic stromal hyperplasia. Paper III: LXRbeta-/- mice are resistant to developing obesity on a high fat diet. As they age, these mice develop pancreatic exocrine insufficiency. By electron microscopy, abnormalities in the pancreatic ducts as well as in the pancreatic secretion were found. Particularly interesting was the presence within the ducts of lamellar structures similar to those seen in cystic fibrosis. With a specific antibody we demonstrated the presence of LXRbeta in the nuclei of epithelial cells lining the pancreatic ducts. We therefore searched for LXR-regulated genes that might influence the density of pancreatic secretion. We found that aquaporin-1 is an LXR-regulated gene highly expressed in the pancreatic ductal epithelium of wild type mice but not LXRbeta-/- mice. Thus LXRbeta plays an important role in controlling pancreatic juice secretion through the regulation of water transport, and the observed resistance to a high fat diet in these LXRbeta-/- mice appears to be due to fat malabsorption secondary to pancreatic insufficiency. Paper IV: As they age, mice which cannot synthesize estrogen (aromatase knock-out mice, ArKO mice), develop severe autoimmune exocrinopathy resembling Sjögren s syndrome (SS), which is not observed in ERalpha-/- or ERbeta-/- mice. Many characteristics typical of human SS were found in these mice: There is B cell hyperplasia in the hematopoietic organs with severe immune cell infiltration in the salivary glands and kidneys, proteolytic fragments of alpha-fodrin in the salivary glands and anti-alpha-fodrin antibodies in the serum. When mice were raised on a phytoestrogen-free diet, there was a mild but significant incidence of infiltration of B lymphocytes in WT mice and severe destructive autoimmune lesions in ArKO mice. In age-matched WT mice fed a diet containing normal levels of phytoestrogen, there were no autoimmune lesions. These findings suggest that estrogen deficiency results in a lympho-proliferative autoimmune disease resembling SS and suggest that estrogen might have clinical value in the prevention or treatment of this disease.
    Note: Dissertation Biovetenskaper och näringslära / Biosciences and Nutrition 2009
    Language: English
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  • 6
    Book
    Book
    London : Duckworth
    UID:
    (DE-627)593145364
    Format: VI, 217 S. , 24cm
    Edition: 1. publ.
    ISBN: 0715638076 , 9780715638071
    Language: English
    Subjects: History
    RVK:
    Keywords: Griechenland ; Ausländer ; China ; Sima, Qian v145-v87 ; Geschichtsschreibung ; Hunnen ; Ethnizität ; Herodotus ; Skythen
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  • 7
    UID:
    (DE-627)1181428769
    Format: 173 Bl.
    Note: Auch online unter http://www.freidok.uni-freiburg.de , Freiburg i. Br., Univ., Diss., 2002
    Language: German
    Subjects: German Studies
    RVK:
    Keywords: Handke, Peter 1942- Der Chinese des Schmerzes ; Sprache ; Geschichte 1983- ; Hochschulschrift
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  • 8
    Online Resource
    Online Resource
    Cambridge : Cambridge University Press
    UID:
    (DE-627)883474352
    Format: 1 Online-Ressource (viii, 338 pages) , digital, PDF file(s)
    ISBN: 9780511920493
    Content: The Huns have often been treated as primitive barbarians with no advanced political organisation. Their place of origin was the so-called 'backward steppe'. It has been argued that whatever political organisation they achieved they owed to the 'civilizing influence' of the Germanic peoples they encountered as they moved west. This book argues that the steppes of Inner Asia were far from 'backward' and that the image of the primitive Huns is vastly misleading. They already possessed a highly sophisticated political culture while still in Inner Asia and, far from being passive recipients of advanced culture from the West, they passed on important elements of Central Eurasian culture to early medieval Europe, which they helped create. Their expansion also marked the beginning of a millennium of virtual monopoly of world power by empires originating in the steppes of Inner Asia. The rise of the Hunnic Empire was truly a geopolitical revolution
    Content: 1. Introduction -- 2. Rome's inner Asian enemies before the Huns -- 3. The Huns in Central Asia -- 4. The Huns in Europe -- 5. The end of the Hunnic Empire in the West -- 6. The later Huns and the birth of Europe -- Conclusion
    Note: Title from publisher's bibliographic system (viewed on 05 Oct 2015)
    Additional Edition: 9781107009066
    Additional Edition: Print version 9781107009066
    Language: English
    Subjects: History
    RVK:
    Keywords: Hunnen ; Eroberung ; Römisches Reich ; Europa ; Politische Kultur
    URL: Volltext  (lizenzpflichtig)
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  • 9
    UID:
    (DE-627)1620187124
    Format: 135 S. , Ill., graph. Darst.
    Note: Hamburg, Univ., Diss., 2001
    Language: German
    Keywords: Hochschulschrift
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  • 10
    Online Resource
    Online Resource
    Berlin : Universität der Künste Berlin
    UID:
    (DE-627)1835023509
    Format: 1 Online-Ressource
    Language: English
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