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  • 1
    Online Resource
    Online Resource
    Cham : Springer International Publishing AG
    UID:
    (DE-627)1752102258
    Format: 1 online resource (235 pages)
    ISBN: 9783319191898
    Series Statement: Topics in Current Chemistry Ser. v.363
    Content: Intro -- Preface -- Contents -- Chemical Protein Synthesis with the KAHA Ligation -- 1 Introduction -- 1.1 Overview of Chemical Ligations for Protein Synthesis -- 1.2 KAHA Ligation -- 1.2.1 Types of KAHA Ligation -- 1.2.2 Mechanism -- Type I -- Type II -- 2 α-Ketoacids -- 2.1 General Properties of α-Keto Acids -- 2.2 Synthesis of Peptide α-Ketoacids -- 2.2.1 Phosphorus Ylides -- 2.2.2 Sulfur Ylides -- 2.3 Solid Supported Linker for Peptide Sulfur-Ylide Synthesis -- 2.4 Protecting Groups for C-Terminal α-Ketoacids -- 3 Hydroxylamines -- 3.1 Overview -- 3.2 O-Unsubstituted Peptide Hydroxylamines -- 3.2.1 On-Resin Synthesis by Nucleophilic Substitution -- 3.2.2 Nitrone-Protected N-Hydroxy Aminoacid Building Blocks -- 3.2.3 In Situ Preparation of Peptides with N-Terminal Nitrone-Protected N-Hydroxy Aminoacids -- 3.2.4 Synthesis of beta-Peptides with Isoxazolidin-5-One Building Blocks -- 3.3 O-Substituted Hydroxylamines -- 3.3.1 OBz Hydroxylamines -- 3.3.2 O-Aryl Hydroxylamines -- 3.3.3 Cyclic Hydroxylamines -- 4 Ligations/Protein Synthesis -- 4.1 Ligations with Type I Hydroxylamines -- 4.2 Ligations with 5-Oxaproline -- 4.2.1 Formation and Rearrangement of Depsipeptides -- 4.2.2 Two-Segment Ligations with 5-Oxaproline -- 4.2.3 Multi-Segment Ligations -- UFM-1 -- SUMO3 -- 4.3 Peptide Macrocycles -- 4.3.1 Macrocyclizations with Free Hydroxylamines: Synthesis of Epi-Aza-Surfactin -- 4.3.2 Synthesis of Natural Products with Nitrone-Protected Monomers -- 4.3.3 General and Efficient Synthesis of Macrocyclic Peptides with 5-Oxaproline -- 5 Potassium Acyltrifluoroborate (KAT) Ligation -- 6 Outlook -- 6.1 Development of New Cyclic Hydroxylamines -- 6.2 Orthogonally Protected α-Ketoacids -- 6.3 Kinetically Controlled Ligations -- 6.4 Combining KAHA Ligation and Native Chemical Ligation -- 6.5 Summary -- References.
    Note: Description based on publisher supplied metadata and other sources
    Additional Edition: 9783319191881
    Additional Edition: Erscheint auch als Druck-Ausgabe 9783319191881
    Language: English
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  • 2
    UID:
    (DE-627)508430615
    Format: Online-Ressource
    Note: auch als Printausgabe , Lübeck, Univ., Diss, 2005
    Language: English
    Keywords: Hochschulschrift
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  • 3
    UID:
    (DE-627)629482861
    Format: graph. Darst.
    ISSN: 0732-8516
    In: The financial review, Malden, Mass. [u.a.] : Blackwell, 1972, 45(2010), 2 vom: Mai, Seite 485-499, 0732-8516
    In: volume:45
    In: year:2010
    In: number:2
    In: month:05
    In: pages:485-499
    Language: English
    Keywords: Aufsatz in Zeitschrift
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  • 4
    UID:
    (DE-627)77791560X
    Format: IX, 138 S. , graph. Darst.
    Note: Heidelberg, Univ., Diss., 2013
    Language: English
    Keywords: Galaxie ; Sternentstehungsgebiet ; Hochschulschrift
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  • 5
    UID:
    (DE-627)1009503901
    Format: Illustrationen
    ISBN: 9783180922942
    Note: Literaturangaben
    In: International Conference on Gears (7. : 2017 : Garching b. München), International Conference on Gears 2017, International Conference on Gear Production 2017, International Conference on High Performance Plastic Gears 2017 ; 1, Düsseldorf : VDI Verlag, 2017, (2017), Seite 457-466, 9783180922942
    In: year:2017
    In: pages:457-466
    Language: English
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  • 6
    Online Resource
    Online Resource
    [Erscheinungsort nicht ermittelbar] : The University of Hong Kong (Pokfulam, Hong Kong)
    UID:
    (DE-627)180331589X
    Content: published_or_final_version ; Medicine ; Doctoral ; Doctor of Philosophy
    Note: Dissertation The University of Hong Kong (Pokfulam, Hong Kong)
    Language: English
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  • 7
    Online Resource
    Online Resource
    Cham [u.a.] : Springer International Publishing
    UID:
    (DE-627)1657021327
    Format: Online-Ressource (VII, 229 p. 235 illus., 69 illus. in color, online resource)
    ISBN: 9783319191898
    Series Statement: Topics in Current Chemistry 363
    Content: Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
    Note: Hydroxyamine ketoacid ligationChemical synthesis of proteins using N-sulfanylethylanilide peptides based on N-S acyl transfer chemistry -- Post ligation Desulfurization: A General Approach for Chemical Protein Synthesis -- Solid phase chemical synthesis of proteins -- New methods for protein chemical synthesis -- the chemical preparation of modified histones.
    Additional Edition: 9783319191881
    Additional Edition: Druckausg. Protein ligation and total synthesis ; 2 Cham : Springer, 2015 9783319191881
    Additional Edition: 9783319369372
    Additional Edition: Druckausg. Protein ligation and total synthesis ; 2 Cham [u.a.] : Springer, 2015 9783319191881
    Additional Edition: 3319191888
    Language: English
    Subjects: Chemistry/Pharmacy
    RVK:
    Keywords: Proteine ; Ligation ; Totalsynthese ; Proteinsynthese ; Aufsatzsammlung
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
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  • 8
    Online Resource
    Online Resource
    UID:
    (DE-627)1656148609
    Format: Online-Ressource (157 S.)
    Note: Mit Zsfassungen in dt. und engl. Sprache , Heidelberg, Univ., Diss., 2015
    Additional Edition: Druckausg. Liu, Lei, 1986 - Multiscale modelling of CTCF and its complexes 2015
    Language: English
    Keywords: Hochschulschrift
    URL: Volltext  (kostenfrei)
    URL: Volltext  (kostenfrei)
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  • 9
    Online Resource
    Online Resource
    [Erscheinungsort nicht ermittelbar] : KIT Scientific Publishing
    UID:
    (DE-627)1778712665
    Format: 1 Online-Ressource (XVI, 363 p.)
    ISBN: 9783866447301
    Content: Dynamic service-oriented environments (SOEs) are characterised by a large number of heterogeneous service components that are expected to support the business as a whole. The present work provides a negotiation-based approach to facilitate automated and multi-level service-level management in an SOE, where each component autonomously arranges its contribution to the whole operational goals. Evaluation experiments have shown an increased responsiveness and stability of an SOE in case of changes
    Note: English
    Language: English
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  • 10
    Book
    Book
    Boca Raton, Fla. [u.a.] : CRC Press
    UID:
    (DE-627)64125346X
    Format: XV, 274 S. , graph. Darst.
    ISBN: 9781439825792
    Note: Includes bibliographical references and index
    Language: English
    Subjects: Computer Science
    RVK:
    Keywords: Computersicherheit
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