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  • 1
    Online-Ressource
    Online-Ressource
    London :Henry Stewart Talks,
    UID:
    (DE-602)edoccha_9961427405802883
    Umfang: 1 videorecording (24 min., 24 sec.) : , sound, color. , 002424
    Serie: Human population genetics I : evolution and variation,
    Inhalt: Audio-visual presentation : The human genome diversity project (HGDP) ; Method structure ; Limitations of HGDP-CEPH ; Are the clusters established by structure "good" races? ; Correlation between genetic and geographic distance ; Decrease of genetic diversity in the human expansion as serial founder effect ; Coevolution of genes and languages ; Linguistic families: correlation of the genetic and linguistic trees ; Darwin's statement ; The complete tree of language evolution.
    Anmerkung: Animated audio-visual presentation with synchronized narration. , Title from title frames. , Contents: The human genome diversity project (HGDP) -- Method structure -- Limitations of HGDP-CEPH -- Are the clusters established by structure "good" races? -- Correlation between genetic and geographic distance -- Decrease of genetic diversity in the human expansion as serial founder effect -- Coevolution of genes and languages -- Linguistic families: correlation of the genetic and linguistic trees -- Darwin's statement -- The complete tree of language evolution.
    Sprache: Englisch
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  • 2
    Online-Ressource
    Online-Ressource
    London :Henry Stewart Talks,
    UID:
    (DE-602)edoccha_9961427406102883
    Umfang: 1 videorecording (39 min., 41 sec.) : , sound, color. , 003941
    Serie: Henry Stewart talks
    Inhalt: Audio-visual presentation : Genetic markers inherited from a single parent ; Mutational history of the Y chromosome (NRY) ; Genealogies of Y chromosome and mitochondria ; Of Adam and Eve ; Primates and Homo sapiens ; Neanderthal and the spread of modern humans from East Africa ; The spread of modern humans according to Y chromosome ; Areas of origin of agriculture and animal breeding ; Spread of cultivated wheat to Europe in the Neolithic period ; Geographic maps of the first three principal components of Europe ; Coevolution and hitchhiking of commensals: Helicobacter pylori ; Coevolution of humans and cattle.
    Anmerkung: Retrieved April 15, 2024, from https://hstalks.com/bs/302/. , Printable Handouts -- Navigable Slide Index -- Introduction -- Genetic markers inherited from a single parent -- NRY and mtDNA form genealogies -- Most recent common ancestor (MRCA) -- Mutation rates -- Mutational history of the Y chromosome (NRY) -- Human NRY chromosome phylogeny explanation -- The phylogeny -- NRY and mitochondria genealogies are similar -- NRY - Stanford University -- mtDNA - Stanford University -- Of Adam and Eve -- All Y chromosomes descend from one male -- How many humans lived at the time? -- Why didn't Adam and Eve live at the same time? -- Primates, genus Homo, species sapiens -- Transition to bipedality -- Bipedality freed hands for making tools -- Growth and expansion to the Old World -- Spread of modern humans from East Africa (1) -- Spread of modern humans from East Africa (2) -- Spread of modern humans from East Africa (3) -- Spread of humans according to Y chromosome -- Map of likely expansion of the Y chromosome -- Areas of origin of agriculture and animal breeding -- Agriculture and animal breeding development areas -- Spread of cultivated wheat to Europe -- The map of spread of cultivated wheat to Europe -- Geographic maps of major migrations in Europe -- The scale of principal components (1) -- The scale of principal components (2) -- The first principal component -- Agricultural diffusion - 1/3 demic and 2/3 cultural -- The second principal component -- The second principal component - map -- The third principal component -- The third principal component - map -- Commensal coevolution and hitchiking: H. pylori -- Similarities of humans and bacteria -- Similar clinal gradients of H. pylori and humans -- Coevolution of humans and cattle -- The migration of Scandinavians to Iceland -- Genetic distances between cattle of different origin -- Etruscans -- Summary.
    Sprache: Englisch
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  • 3
    Online-Ressource
    Online-Ressource
    London :Henry Stewart Talks,
    UID:
    (DE-602)edoccha_9961427406202883
    Umfang: 1 videorecording (48 min., 09 sec.) : , sound, color. , 004809
    Serie: Henry Stewart talks
    Inhalt: Audio-visual presentation : Four major factors of evolution: mutation, natural selection, drift, migration ; Role of demography in the quantitative study of evolution ; Drift: the Parma Valley study ; Equilibrium of migration and drift ; Founders' effect ; Reconstructing evolutionary history of a population ; Evidence of the importance of drift from molecular evolution ; Molecular evolution of proteins ; Trees with proteins and trees with DNA ; Phylogeographic analysis ; Microsatellites ; Graphic presentation of evolution data by principal components analysis.
    Anmerkung: Retrieved April 15, 2024, from https://hstalks.com/bs/301/. , Printable Handouts -- Navigable Slide Index -- Introduction -- How do we describe genetic variation? -- Four major factors of evolution: mutation -- Natural selection and drift -- Migration -- Role of demography in the study of evolution -- Calculating selection rate -- Balancing selection -- Drift and population size -- Drift and migration -- Drift, once the Cinderella of evolution -- The aim of the Parma valley study -- Computing expected genetic variation due to drift -- Computer simulation of drift in 22 villages -- Results of the computer simulation -- Equilibrium of migration and drift -- Calculation of drift in larger populations -- Population density and drift in the Parma valley -- Genetic variation plotted against population density -- Simulations of expected effect of drift on variation -- Simulation conclusions -- How fast is fixation or extinction under drift ? -- Founders' effect -- Evolutionary history and present genetic variation -- Prediction of evolutionary history using drift -- Model for evolution reconstruction -- The first application of the model -- Genetic distances based on blood groups (1) -- Genetic distances based on blood groups (2) -- Tree of evolution -- Is drift the only evolutionary factor involved? -- Anthropometric vs. genetic world tree -- Major differences between the two trees -- Conclusions (Cavalli-Sforza and Edwards, 1964) -- Molecular evolution reinforces importance of drift -- Kimura's theorem on molecular evolution (1) -- Kimura's theorem on molecular evolution (2) -- Molecular evolution of proteins -- Rate of molecular evolution varies among proteins -- Trees with proteins, trees with DNA -- An example of philogeographic analysis (1) -- An example of philogeographic analysis (2) -- Microsatellites -- Using microsatellites to define populations -- A tree with 30 microsatellites (1) -- A tree with 30 microsatellites (2) -- Graphic presentation of evolution data by PCA -- Eigenvalues and eigenvectors -- Understanding PCA -- PCA of 21 European populations (1) -- PCA of 21 European populations (2) -- Same European populations analyzed by tree.
    Sprache: Englisch
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  • 4
    Online-Ressource
    Online-Ressource
    London :Henry Stewart Talks,
    UID:
    (DE-602)edoccha_9961427002202883
    Umfang: 1 videorecording (27 min., 25 sec.) : , sound, color. , 002725
    Serie: The biomedical & life sciences collection,
    Anmerkung: Animated audio-visual presentation with synchronized narration. , Title from title frames. , Contents: Therapeutic options -- Management of IPF -- The ASCEND study -- INPULSIS 1 and 2 studies.
    Sprache: Englisch
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  • 5
    Online-Ressource
    Online-Ressource
    London :Henry Stewart Talks,
    UID:
    (DE-602)edoccha_9961427215902883
    Umfang: 1 online resource (1 streaming video file (16 min.)) : , sound, color
    Serie: Evolution and medicine : how new applications advance research and practice,
    Anmerkung: Animated audio-visual presentation with synchronized narration. , Title from publisher's web site. , Contents: Depression has a genetic component and can be triggered by stress -- It is a common mental illness -- Why has it not been selected out? -- Sadness is adaptive but depression is probably not -- Depression can be thought of as sadness becoming excessive and malignant.
    Sprache: Englisch
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  • 6
    Online-Ressource
    Online-Ressource
    London :Henry Stewart Talks Ltd,
    UID:
    (DE-602)edoccha_9961427410202883
    Umfang: videorecording (48 min., 21 sec.) , 004821
    Inhalt: Audio-visual presentation : Trypanosomes: causative agents of neglected diseases ; Uniqueness of redox metabolism in trypanosomes ; Detoxification of hydroperoxides and peroxynitrite ; Biosynthesis and function of trypanothione ; Validation of targets for trypanocidal drugs.
    Anmerkung: Retrieved April 15, 2024, from https://hstalks.com/bs/394/. , Introduction -- Chemical world divided to oxidants/antioxidants -- Oxidants -- The lesson from Berny Babior -- The toxic oxidant cocktail -- Therapeutic approach to treat infectious diseases -- Selective inhibition of pathogen defense systems -- Trypanosomatids -- Hydroperoxide metabolism in mammals -- Trypanosomes have different oxidants metabolism -- Unique antioxidants defense in trypanosomes -- What is trypanothione? -- The search for TPx homologous to GPx -- The break through in 1997 -- Oxidoreductases system components -- Comparing TXN and Trx -- How does trypanothione interact with TXN? -- Reduced and oxidized active site of TXN -- Proof of essentiality of C41 and C43 in TXN -- The tool to study interaction of TXN - T(SH)2 -- Structure of TXN reacted with a pseudo-substrate -- First steps of the catalytic cycle -- Information from site-directed mutagenesis of TXN -- Tryparedoxin in action -- Unusual mechanism: the "perverted induced fit" -- A 2-cysteine peroxiredoxin -- Pioneering in the field of peroxiredoxins -- The "new" peroxidase family: peroxiredoxins -- How does TXNPx interact? -- General reaction scheme of Prx -- Variations of the Prx reaction scheme -- The oxidative steps of the catalytic system -- Reaction scheme of TXNPx I: oxidative steps -- N-terminal catalytic triad of a Prx -- Inter-subunit disulfide formation in TXNPx -- The reductive steps of the catalytic system -- Reaction scheme of TXNPx 2: reductive steps -- TXN attacking TXNPx at the CR (C173') -- Using same tools to study TXN /TXNPx interaction -- Tryptic peptides linking TXNPx to TXN C44S -- Reduced TXNPx from T. cruzi -- Dead end intermediate of TXNPx and TXNC44S -- Modeling the intermediate to averaged EM images -- Shapes of Tb TXNPx -- MOLISA logo - molecular links of TXN and TXNPx -- Ranges of rate constants of Prx's -- Thiol-dependent hydroperoxide metabolism (1) -- Thiol-dependent hydroperoxide metabolism (2) -- Other functions of the T(SH)2 TXN couple -- Nothing works without trypanothione -- Where should the cycle be arrested? -- Validation of TryR as drug target -- Circumstantial evidence for therapeutic validity -- Inhibition of the biosynthesis of trypanothione -- Biosynthesis of trypanthione in trypanosomes -- Validation of TryS as drug target by dsRNAi -- Simulation of oxidative burst -- TryS-deficient T.brucei in oxidative challenge -- HTS for TryS inhibitors -- MOLISA's new paullone series of TryS inhibitors -- Summary -- Acknowledgements -- Thank you.
    Sprache: Englisch
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  • 7
    Online-Ressource
    Online-Ressource
    London :Henry Stewart Talks,
    UID:
    (DE-602)edoccha_9961427582002883
    Umfang: 1 videorecording (51 min., 14 sec.) , 005114
    Serie: The biomedical & life sciences collection,
    Anmerkung: Animated audio-visual presentation with synchronized narration. , Title from title frames. , Contents: Fibrosis: a common pathway to organ failure -- Interstitial lung disease: idiopathic interstitial pneumonia -- Idiopathic Pulmonary Fibrosis: definition -- IPF epidemiology -- Causes of the disease -- Pathogenesis of IPF -- Diagnostic approach.
    Sprache: Englisch
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  • 8
    UID:
    (DE-602)b3kat_BV023982351
    Umfang: 1 Videokassette (VHS, 45 Min.)
    Anmerkung: Fernsehmitschnitt: BR 3 18.01.1993
    Sprache: Unbestimmte Sprache
    Schlagwort(e): Weiße Rose ; Scholl, Hans 1918-1943 ; Scholl, Sophie 1921-1943
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 9
    Online-Ressource
    Online-Ressource
    [Place of publication not identified] :Pearson IT Certification,
    UID:
    (DE-602)edocfu_9961555633002883
    Umfang: 1 online resource (1 streaming video file (51 hr., 44 min., 31 sec.)) : , digital, sound, color
    ISBN: 0-13-451027-5
    Serie: LiveLessons (Indianapolis, Ind.)
    Inhalt: "CompTIA A+ 220-901 and 220-902 Certification Learning Path is a unique video product that provides complete coverage of all the CompTIA A+ 220-901 and 220-902 objectives so you can study for and pass the exams The training provided in this Learning Path which includes the CompTIA A+ 220-901 and CompTIA 220-902 Complete Video Courses plus CompTIA A+ Troubleshooting Techniques--provides targeted and concise hands-on training that walks you through a learning path to successfully understand and absorb all key exam concepts. The modules in this course cover every objective in the CompTIA A+ 220-901 and 220-902 exams and can be used as your sole resource for learning the material needed to study for and pass both A+ exams. You can also use this as a supplement to other A+ training. Additional troubleshooting concepts are discussed and analyzed so you can get quick, concise, hands-on, solutions for the real world. The videos in these courses map to the main objectives of the CompTIA A+ 220-901 and 220-902 certifications. The videos include the author building a computer live on camera so you can see first-hand how to accomplish key tasks. He also includes hands-on configuration labs; laptop, smartphone and device hardware labs; and live-action troubleshooting labs in addition to hands-on networking, OS and UI demos, real-world troubleshooting methods and security concepts and hands-on solutions. With over 50 hours of hands-on demonstrations, live training, animations, and video screencasting, this Learning Path provides all the coverage you need to pass the exams."--Resource description page.
    Anmerkung: Title and publication information from resource description page (Safari, viewed June 2, 2016). , CompTIA A+ complete video course library (220-901 + 220-902) -- CompTIA A+ complete video course (220-902) -- CompTIA A+ troubleshooting techniques.
    Sprache: Englisch
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  • 10
    Online-Ressource
    Online-Ressource
    London :Henry Stewart Talks,
    UID:
    (DE-602)edoccha_9961426981502883
    Umfang: 1 videorecording (11 min., 59 sec.) : , sound, color. , 001159
    Serie: Non-clinical testing for toxicity of pharmaceuticals : regulatory and practical standards for testing and application,
    Anmerkung: Animated audio-visual presentation with synchronized narration. , Title from title frames. , Contents: Medical device -- Medical device combination product -- Biocompatibility -- ISO standards -- Biological safety tests.
    Sprache: Englisch
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