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  • Walter de Gruyter GmbH  (453)
  • 2015-2019  (453)
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  • Walter de Gruyter GmbH  (453)
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  • 2015-2019  (453)
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  • 1
    Online Resource
    Online Resource
    Similar complication rates for irreversible electroporation and thermal ablation in patients with hepatocellular tumors
    Walter de Gruyter GmbH ; 2019
    In:  Radiology and Oncology Vol. 53, No. 1 ( 2019-03-03), p. 116-122
    Details
    In: Radiology and Oncology, Walter de Gruyter GmbH, Vol. 53, No. 1 ( 2019-03-03), p. 116-122
    Abstract: To compare the frequency of adverse events of thermal microwave (MWA) and radiofrequency ablation (RFA) with non-thermal irreversible electroporation (IRE) in percutaneous ablation of hepatocellular carcinoma (HCC). Patients and methods We retrospectively analyzed 117 MWA/RFA and 47 IRE procedures (one tumor treated per procedure; 144 men and 20 women; median age, 66 years) regarding adverse events, duration of hospital and intensive care unit (ICU) stays and occurrence of a post-ablation syndrome. Complications were classified according to the Clavien & Dindo classification system. Results 70.1% of the RFA/MWA and 63.8% of the IRE procedures were performed without complications. Grade I and II complications (any deviation from the normal postinterventional course, e.g., analgesics) occurred in 26.5% (31/117) of MWA/RFA and 34.0% (16/47) of IRE procedures. Grade III and IV (major) complications occurred in 2.6% (3/117) of MWA/RFA and 2.1% (1/47) of IRE procedures. There was no significant difference in the frequency of complications (p = 0.864), duration of hospital and ICU stay and the occurrence of a post-ablation syndrome between the two groups. Conclusions Our results suggest that thermal (MWA and RFA) and non-thermal IRE ablation of malignant liver tumors have comparable complication rates despite the higher number of punctures and the lack of track cauterization in IRE.
    Type of Medium: Online Resource
    ISSN: 1581-3207
    URL: Article
    DOI: 10.2478/raon-2019-0011
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2019
    detail.hit.zdb_id: 2134813-3
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  • 2
    Online Resource
    Online Resource
    Coherent multicore methodology and tooling
    Walter de Gruyter GmbH ; 2017
    In:  it - Information Technology Vol. 59, No. 5 ( 2017-11-27), p. 233-241
    Details
    In: it - Information Technology, Walter de Gruyter GmbH, Vol. 59, No. 5 ( 2017-11-27), p. 233-241
    Abstract: In the mobility domains functions are often realized by software running on Electronic Control Units (ECU)s, which are interconnected in a network of ECU. Nowadays there is a trend to move to ECUs with multicore processors which imposes a major challenge: An increasing degree of parallelism. This additional parallelism when migrating existing software that has been developed for singlecore systems, to a multicore system, has to be used in an efficient way. Furthermore, an increase in parallelism can cause concurrent executions of software functions, which are not possible when being executed on a singlecore ECU. This makes reasoning about the software behaviour much more difficult and also poses problems during certification activities, when sufficient independence between functions needs to be ensured. Therefore tool support is absolutely necessary to address the challenges. In this article we describe methods and tools that have been developed and/or extended during the ARAMiS project to address particular challenges arising during the development of multicore systems. In general these challenges result from the incr ease in parallelism available in multicore architectures.
    Type of Medium: Online Resource
    ISSN: 2196-7032 , 1611-2776
    URL: Article
    DOI: 10.1515/itit-2017-0024
    RVK:
    SQ 1100
    RVK:
    SA 5445
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2017
    detail.hit.zdb_id: 2102301-3
    detail.hit.zdb_id: 144419-0
    detail.hit.zdb_id: 165820-7
    detail.hit.zdb_id: 2028598-X
    detail.hit.zdb_id: 6242-X
    detail.hit.zdb_id: 1146417-3
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  • 3
    Online Resource
    Online Resource
    Automatisierung in der Arbeitsplanung : Ergebnisse einer Studie
    Walter de Gruyter GmbH ; 2017
    In:  Zeitschrift für wirtschaftlichen Fabrikbetrieb Vol. 112, No. 12 ( 2017-12-18), p. 827-830
    Details
    In: Zeitschrift für wirtschaftlichen Fabrikbetrieb, Walter de Gruyter GmbH, Vol. 112, No. 12 ( 2017-12-18), p. 827-830
    Abstract: Effizienzsteigerungen in der Arbeitsplanung werden vor dem Hintergrund kurzer Produktlebenszyklen und kundenindividueller Produkte immer wichtiger. Daher hat das Werkzeugmaschinenlabor WZL der RWTH Aachen eine Studie*) durchgeführt, um Handlungsbedarfe zu identifizieren. Ein wesentliches Ergebnis der Studie ist ein trotz des weit verbreiteten Einsatzes von Arbeitsplanungssoftware bestehender Bedarf der Reduktion des Konfigurationsaufwands sowie der Aufwände zur Aktualisierung der Planungsgrundlage.
    Type of Medium: Online Resource
    ISSN: 2511-0896 , 0947-0085
    URL: Article
    DOI: 10.3139/104.111844
    RVK:
    ZG 1100
    RVK:
    QA 10000
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2017
    detail.hit.zdb_id: 2133068-2
    detail.hit.zdb_id: 1225290-6
    SSG: 3,2
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  • 4
    Online Resource
    Online Resource
    High-sensitivity cardiac troponin I in the general population – defining reference populations for the determination of the 99th percentile in the Gutenberg Health Study
    Walter de Gruyter GmbH ; 2015
    In:  Clinical Chemistry and Laboratory Medicine (CCLM) Vol. 53, No. 5 ( 2015-01-1)
    Details
    In: Clinical Chemistry and Laboratory Medicine (CCLM), Walter de Gruyter GmbH, Vol. 53, No. 5 ( 2015-01-1)
    Abstract: The 99th percentile of cardiac troponin levels, determined in a reference population, is accepted as threshold for diagnosis of acute myocardial infarction (AMI). However, there is no common consensus of how to define the reference population. The aim of the present study was to determine 99th percentile reference values, determined by a high-sensitivity assay (hsTnI), according to different health status and cardiovascular risk factor prevalence in a large population-based sample. Troponin I was determined using the Abbott ARCHITECT STAT highly sensitive troponin I immunoassay in 4138 participants of the Gutenberg Health Study. hsTnI was detectable in 81.6% of all individuals. The 99th percentile of the overall population was 27 ng/L. Age and gender had a prominent influence on these values. Exclusion of individuals with elevated natriuretic peptide levels or cardiac abnormalities resulted in lower 99th percentile values, whereas exclusion of individuals with an impaired estimated glomerular filtration rate (eGFR) or with prevalent coronary artery disease/myocardial infarction (CAD/MI) did not result in a meaningful change. Troponin I, measured by a high-sensitivity assay, can be reliably detected in the vast majority of the general population. hsTnI values were dependent on age, gender as well as structural and functional cardiac abnormalities.
    Type of Medium: Online Resource
    ISSN: 1437-4331 , 1434-6621
    URL: Article
    DOI: 10.1515/cclm-2014-0619
    Language: Unknown
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2015
    detail.hit.zdb_id: 1492732-9
    SSG: 15,3
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  • 5
    Online Resource
    Online Resource
    Multi-Frequency Pulsed Overhauser DNP at 1.2 Tesla
    Walter de Gruyter GmbH ; 2017
    In:  Zeitschrift für Physikalische Chemie Vol. 231, No. 3 ( 2017-3-1), p. 561-573
    Details
    In: Zeitschrift für Physikalische Chemie, Walter de Gruyter GmbH, Vol. 231, No. 3 ( 2017-3-1), p. 561-573
    Abstract: Dynamic nuclear polarization (DNP) is a methodology to increase the sensitivity of nuclear magnetic resonance (NMR) spectroscopy. It relies on the transfer of the electron spin polarization from a radical to coupled nuclear spins, driven by microwave excitation resonant with the electron spin transitions. In this work we explore the potential of pulsed multi-frequency microwave excitation in liquids. Here, the relevant DNP mechanism is the Overhauser effect. The experiments were performed with TEMPOL radicals in aqueous solution at room temperature using a Q-band frequency (1.2 T) electron paramagnetic resonance (EPR) spectrometer combined with a Minispec NMR spectrometer. A fast arbitrary waveform generator (AWG) enabled the generation of multi-frequency pulses used to either sequentially or simultaneously excite all three 14 N-hyperfine lines of the nitroxide radical. The multi-frequency excitation resulted in a doubling of the observed DNP enhancements compared to single-frequency microwave excitation. Q-band free induction decay (FID) signals of TEMPOL were measured as a function of the excitation pulse length allowing the efficiency of the electron spin manipulation by the microwave pulses to be extracted. Based on this knowledge we could quantitatively model our pulsed DNP enhancements at 1.2 T by numerical solution of the Bloch equations, including electron spin relaxation and experimental parameters. Our results are in good agreement with theoretical predictions. Whereas for a narrow and homogeneous single EPR line continuous wave excitation leads to more efficient DNP enhancements compared to pulsed excitation for the same amount of averaged microwave power. The situation is different for radicals with several hyperfine lines or in the presence of inhomogeneous line broadening. In such cases pulsed single/multi-frequency excitation can lead to larger DNP enhancements.
    Type of Medium: Online Resource
    ISSN: 2196-7156 , 0942-9352
    URL: Article
    DOI: 10.1515/zpch-2016-0844
    RVK:
    VA 8450
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2017
    detail.hit.zdb_id: 201103-7
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  • 6
    Online Resource
    Online Resource
    Präsentationsformen der externen Wissenschaftskommunikation: Ein Vorschlag zur Typologisierung
    Walter de Gruyter GmbH ; 2017
    In:  Zeitschrift für Angewandte Linguistik Vol. 2017, No. 66 ( 2017-09-26), p. 81-113
    Details
    In: Zeitschrift für Angewandte Linguistik, Walter de Gruyter GmbH, Vol. 2017, No. 66 ( 2017-09-26), p. 81-113
    Abstract: This article proposes a typology for forms of presentations for external science communication. It incorporates theoretical concepts but remains applicable for science communication in practice. Empirical basis is a systematic screening and study of established forms as part of the research project “Science In Presentations”. The following differentiation criteria are used: the degree of multimodality, the degree of interactivity, the degree of event and entertainment orientation and the degree of performance. The typology is exemplified by four real case studies, for which respectively one criterion is especially pronounced: Science Vision (multimodality), Science Café (interactivity), Science Slam (event and entertainment orientation) and Christmas Lecture (performance).
    Type of Medium: Online Resource
    ISSN: 2190-0191 , 1433-9889
    URL: Article
    DOI: 10.1515/zfal-2017-0019
    RVK:
    EQ 1000
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2017
    detail.hit.zdb_id: 1395566-4
    detail.hit.zdb_id: 2445275-0
    SSG: 7,11
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  • 7
    Online Resource
    Online Resource
    Fully guided placement of orthodontic miniscrews— a technical report
    Walter de Gruyter GmbH ; 2019
    In:  Australasian Orthodontic Journal Vol. 35, No. 1 ( 2019-01-01), p. 71-74
    Details
    In: Australasian Orthodontic Journal, Walter de Gruyter GmbH, Vol. 35, No. 1 ( 2019-01-01), p. 71-74
    Abstract: Orthodontic miniscrews are used to obtain skeletal anchorage during orthodontic treatment and their application is growing due to the simple method of placement and removal, which invites improved patient compliance without significant impact on function and aesthetics. However, complications and risks are reported that underscore the need for a thorough preoperative assessment to enable accurate placement, especially in confined sites. A novel approach is presented which employs a custom-designed 3D-printed splint to facilitate a fully-guided placement of orthodontic miniscrews. Materials and methods The presented splint was virtually planned using coDiagnostiX® software after matching the DICOM data and STL file, to enable fully-guided screw insertion. Insertion depth was defined by a sleeve tube height that provided a depth stop when contact was reached with the head of the hand piece. Additionally, to prevent movement of the insertion instrument, a custom metallic sleeve was designed and 3D-printed by a metallic printer. Results Accurate placement was achieved and no complications were experienced during insertion and use. Conclusions The insertion approach provides more predictable results and enables accurate placement of orthodontic screws. The procedure avoids associated risks and complications primarily encountered in difficult cases.
    Type of Medium: Online Resource
    ISSN: 2207-7480
    URL: Article
    DOI: 10.21307/aoj-2020-035
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2019
    detail.hit.zdb_id: 2905232-4
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  • 8
    Online Resource
    Online Resource
    Entwicklung und Optimierung eines piezoelektrischen Energy-Harvesting-Systems zur Energieversorgung eines Güterverfolgungssystems im Logistikbereich
    Walter de Gruyter GmbH ; 2018
    In:  tm - Technisches Messen Vol. 85, No. 11 ( 2018-11-27), p. 645-657
    Details
    In: tm - Technisches Messen, Walter de Gruyter GmbH, Vol. 85, No. 11 ( 2018-11-27), p. 645-657
    Abstract: Es wird die Entwicklung und Optimierung eines piezoelektrischen Energy-Harvesting-Systems zur autarken Energieversorgung einer Güterverfolgungsanwendung im Logistikbereich vorgestellt. Das Energy-Harvesting-System ist zusammen mit einem Funksender an einem zu ortenden Objekt angebracht. Durch Erschütterungen bei Bewegung des Objekts wird solange elektrische Energie gewandelt und zwischengespeichert, bis genügend vorhanden ist, um eine ortbare Funknachricht mit der Identifikationsnummer des Objekts zu senden. Zur Entwicklung des Harvesters werden zunächst Designkriterien für die optimale Geometrie biegebalkenbasierter piezoelektrischer Energy-Harvester anhand analytischer Methoden ermittelt. Im Anschluss wird das Harvesting-System auf die mechanische Anregung und den elektrischen Energiebedarf hin absolut dimensioniert. Um auch das nichtlineare elektrische Netzwerk zur Energieextraktion und dessen Rückwirkung auf den Harvester korrekt zu berücksichtigen, kommt hierbei ein spezieller modal reduzierter Simulationsansatz in Verbindung mit realistischen Finite-Elemente-Simulationen zum Einsatz. Anschließend wird die Energieextraktionsschaltung hinsichtlich ihrer Energieextraktions-Effizienz und der Einsetzbarkeit für verschiedene Anregungsszenarien ausgelegt. Die Funktionalität des Energy-Harvesting-Systems, bestehend aus Energy-Harvester, Energieextraktionsnetzwerk und Funkschaltung, konnte abschließend für verschiedene Anregungsszenarien nachgewiesen werden.
    Type of Medium: Online Resource
    ISSN: 2196-7113 , 0171-8096
    URL: Article
    DOI: 10.1515/teme-2017-0102
    RVK:
    ZG 1100
    RVK:
    ZS 0001
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2018
    detail.hit.zdb_id: 2025790-9
    SSG: 15,3
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  • 9
    Online Resource
    Online Resource
    Iterativer Spektralfilterentwurf für eine genaue optische Bestimmung von Materialanteilen / Iterative spectral filter design for a precise optical estimation of material abundances
    Walter de Gruyter GmbH ; 2018
    In:  tm - Technisches Messen Vol. 85, No. s1 ( 2018-09-01), p. s110-s116
    Details
    In: tm - Technisches Messen, Walter de Gruyter GmbH, Vol. 85, No. s1 ( 2018-09-01), p. s110-s116
    Abstract: Spectral information provided by hyperspectral images (HSI) enables to determine material abundances in mixtures. The acquisition and processing of HSIs is time-consuming and computationally intensive. For this reason, an approach based on spectral filtering is proposed. Instead of HSIs, the use of a spectral filters leads to the acquisition of a single intensity image. Depending on the design of the spectral filter, this intensity image holds information such as the abundances of a material. Within the scope of this work, we examine the design of spectral filters accounting for iterative approaches. Existing methods are investigated to be used for an optical determination of material abundances, and a new approach including several stages to estimate material abundances is presented.
    Type of Medium: Online Resource
    ISSN: 2196-7113 , 0171-8096
    URL: Article
    DOI: 10.1515/teme-2018-0037
    RVK:
    ZG 1100
    RVK:
    ZS 0001
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2018
    detail.hit.zdb_id: 2025790-9
    SSG: 15,3
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  • 10
    Online Resource
    Online Resource
    Properties of the high burnup structure in nuclear light water reactor fuel
    Walter de Gruyter GmbH ; 2017
    In:  Radiochimica Acta Vol. 105, No. 11 ( 2017-11-27), p. 893-906
    Details
    In: Radiochimica Acta, Walter de Gruyter GmbH, Vol. 105, No. 11 ( 2017-11-27), p. 893-906
    Abstract: The formation of the high burnup structure (HBS) is possibly the most significant example of the restructuring processes affecting commercial nuclear fuel in-pile. The HBS forms at the relatively cold outer rim of the fuel pellet, where the local burnup is 2–3 times higher than the average pellet burnup, under the combined effects of irradiation and thermo-mechanical conditions determined by the power regime and the fuel rod configuration. The main features of the transformation are the subdivision of the original fuel grains into new sub-micron grains, the relocation of the fission gas into newly formed intergranular pores, and the absence of large concentrations of extended defects in the fuel matrix inside the subdivided grains. The characterization of the newly formed structure and its impact on thermo-physical or mechanical properties is a key requirement to ensure that high burnup fuel operates within the safety margins. This paper presents a synthesis of the main findings from extensive studies performed at JRC-Karlsruhe during the last 25 years to determine properties and behaviour of the HBS. In particular, microstructural features, thermal transport, fission gas behaviour, and thermo-mechanical properties of the HBS will be discussed. The main conclusion of the experimental studies is that the HBS does not compromise the safety of nuclear fuel during normal operations.
    Type of Medium: Online Resource
    ISSN: 2193-3405 , 0033-8230
    URL: Article
    DOI: 10.1515/ract-2017-2831
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2017
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