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  • 1
    Online Resource
    Online Resource
    The Prevalence of Human Herpes Virus Type 8 in Semen Specimens of HIV-Negative Iranian Population Detected by Nested Polymerase Chain Reaction
    Briefland ; 2019
    In:  International Journal of Cancer Management Vol. 12, No. 9 ( 2019-09-22)
    Details
    In: International Journal of Cancer Management, Briefland, Vol. 12, No. 9 ( 2019-09-22)
    Type of Medium: Online Resource
    ISSN: 2538-4422 , 2538-497X
    URL: Journal
    URL: Article
    DOI: 10.5812/ijcm
    DOI: 10.5812/ijcm.90667
    Language: Unknown
    Publisher: Briefland
    Publication Date: 2019
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  • 2
    Online Resource
    Online Resource
    The Impact of Local Pressure on Needle Puncture Pain Severity During Spinal Anesthesia in Patients with Elective Surgery Under Spinal Anesthesia: A Randomized, Single-Blinded, Controlled Clinical Trial
    Briefland ; 2023
    In:  Trends in Medical Sciences Vol. 3, No. 1 ( 2023-08-22)
    Details
    In: Trends in Medical Sciences, Briefland, Vol. 3, No. 1 ( 2023-08-22)
    Abstract: Background: Spinal anesthesia is one of the most common and safest methods of anesthesia. However, a challenge for patients who are candidates for spinal anesthesia is the pain caused by inserting the spinal needle. It seems possible to reduce needle pain with local pressure, based on the gate control theory in spinal anesthesia. Objectives: This clinical trial aims to evaluate the effect of applying local pressure on the intensity of pain caused by needles during spinal anesthesia. Methods: In this study, 120 adult patients aged 18 - 50 who were scheduled for elective surgery under spinal anesthesia and had an American Society of Anesthesiologists (ASA) I-III were randomly assigned to the control and intervention groups. In the intervention group, just before inserting the spinal needle, a local pressure of about 5 kg using the thumb was applied to the skin at the needle insertion point for 15 seconds. The control group received routine anesthesia. The severity of needle pain was compared between the two groups using the verbal rating scale (VRS) tool. Results: The incidence of mild pain in the intervention and control groups was 78.7% and 60%, respectively. Also, the control group experienced higher levels of moderate and severe pain compared to the intervention group. In addition, patients in the control group had a higher chance (odds ratio (OR): 3.4, 95% confidence interval (CI): 1.5 - 7.8, P = 0.039) of experiencing moderate to severe pain compared to the intervention group. Pain intensity was significantly lower in patients with a spinal anesthesia history (P = 0.028). Conclusions: Our findings showed that applying local pressure on the skin before inserting a spinal needle can effectively reduce pain during spinal anesthesia. However, further studies with a larger sample size are necessary to confirm the effects of applying local pressure to reduce needle pain during spinal anesthesia.
    Type of Medium: Online Resource
    ISSN: 2783-2090
    URL: Journal
    URL: Article
    DOI: 10.5812/tms
    DOI: 10.5812/tms-134820
    Language: Unknown
    Publisher: Briefland
    Publication Date: 2023
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  • 3
    Online Resource
    Online Resource
    Multicentric Study of Clinicopathological Features of Primary Gastrointestinal Lymphoma of Iran: from 2011 - 2016
    Briefland ; 2021
    In:  International Journal of Cancer Management Vol. 14, No. 6 ( 2021-07-05)
    Details
    In: International Journal of Cancer Management, Briefland, Vol. 14, No. 6 ( 2021-07-05)
    Abstract: Background: Gastrointestinal (GI) tract is the most common site for extranodal lymphoma. The primary GI lymphoma pattern in Iran is different from western countries and has been changed during the past 40 years. Objectives: This study was done to determine the clinical and pathological characteristics of primary GI lymphoma in Tehran, Hamedan, and Mashhad regions in Iran. Methods: In this cross-sectional comparative-descriptive study, 200 patients with primary GI lymphoma in Tehran, Hamadan, and Mashhad regions from 2011 to 2016 were enrolled in a consecutive manner, where the clinical and pathological characteristics of cases were determined. Results: Among 200 patients, 141 (70.5%) subjects were male and 59 (29.5%) subjects were female. The mean age at diagnosis was 54.3 ± 19.3 years. Also, 84%, 8.5%, and 7.5% of the patients’ specimens were from Tehran, Hamedan, and Mashhad, respectively. The stomach was the principal involved location in approximately half of the cases. Diffuse large B-cell lymphoma (DLBCL), was the main subtype that was observed in 64% of the cases. Treatment in 72% of cases was a combination of surgery and chemotherapy. The 5-year survival was assessed in 147 patients with a rate of 68%. Conclusions: Primary GI lymphoma is seen more in male subjects younger than 60 years of age with non-specific symptoms. Also, DLBCL and MALToma are the main histologic types, and the 5-year survival for all cases is 68.0%. The clinical symptoms showed no specific pattern and accordingly, patients with weight loss and abdominal pain should be considered in in differential diagnosis of malignant lymphoma.
    Type of Medium: Online Resource
    ISSN: 2538-4422 , 2538-497X
    URL: Journal
    URL: Article
    DOI: 10.5812/ijcm
    DOI: 10.5812/ijcm.97892
    Language: Unknown
    Publisher: Briefland
    Publication Date: 2021
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  • 4
    Online Resource
    Online Resource
    The Effect of Harm-reducing Programs in Drop-in Centers on the Frequency of High-Risk Behaviors Among Injecting Drug Users in Hamadan
    Briefland ; 2023
    In:  Shiraz E-Medical Journal Vol. 24, No. 5 ( 2023-07-09)
    Details
    In: Shiraz E-Medical Journal, Briefland, Vol. 24, No. 5 ( 2023-07-09)
    Abstract: Background: It is necessary to study high-risk behaviors among intravenous drug users, as well as the effectiveness of the syringe-needle program to help health officials adopt appropriate health policies in order to promote public health services. Therefore, it is necessary to gather and present up-to-date evidence on the effectiveness of these interventions. Methods: The study aimed to evaluate a harm-reducing program using a self-report tool before and after implementing an interventional program, consisting of training on low-risk injection methods, sterilization methods for injection devices, reducing the risks of drug abuse and sexual behaviors, HIV and hepatitis B counseling and testing, apportioning sterile syringes, needles, cotton, alcohol, and condoms, offering methadone maintenance treatment, collecting and discarding contaminated needles, and referral of patients to specialized medical centers. These procedures were performed in two drop-in centers (DIC) in Hamadan. Participants were recruited by the census, including 188 volunteers from the DICs. Descriptive statistics for quantitative variables were mean and standard deviation. Absolute and relative frequencies were used for ranked and categorized variables. Analytical analysis for high-risk behaviors before and after the intervention was performed using the tests related to paired data and, if necessary, regression models (P ≤ 0.05). STATA version 12 was used to analyze the data. Results: A total of 188 people participated in this study, of whom 112 (59.6%) were male, and 76 (40.4%) were female. The mean ± standard deviation of the age of the participants was 47.72 ± 10.88. The results showed that the proportions of non-injecting drug users (P = 0.03), injecting drug users (P = 0.008), and co-injection users (P 〈 0.001) were significantly different compared before admission to the DICs and two months after discharge (P = 0.03). Conclusions: Programs of DICs, especially educational programs and distributing syringes and needles, play a significant role in reducing high-risk behaviors, at least in the short term. As a result, this practice may help reduce the incidence of HIV and other diseases transmitted through joint injections among drug users.
    Type of Medium: Online Resource
    ISSN: 1735-1391
    URL: Journal
    URL: Article
    DOI: 10.5812/semj
    DOI: 10.5812/semj-132283
    Language: Unknown
    Publisher: Briefland
    Publication Date: 2023
    detail.hit.zdb_id: 2060231-5
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    BTU Cottbus
    Wissenschaftspark Albert Einstein
    EUV Frankfurt
    TH Wildau
    FH Potsdam
  • 5
    Online Resource
    Online Resource
    Compatibility of Intraoperative Frozen Section Analysis with Permanent Section Analysis of Sentinel Lymph Nodes in Breast Cancer
    Briefland ; 2017
    In:  International Journal of Cancer Management Vol. 10, No. 9 ( 2017-09-30)
    Details
    In: International Journal of Cancer Management, Briefland, Vol. 10, No. 9 ( 2017-09-30)
    Type of Medium: Online Resource
    ISSN: 2538-4422 , 2538-497X
    URL: Journal
    URL: Article
    DOI: 10.5812/ijcm
    DOI: 10.5812/ijcm.11571
    Language: Unknown
    Publisher: Briefland
    Publication Date: 2017
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  • 6
    Online Resource
    Online Resource
    Sarcomas Epidemiology in Iran: Analysis of Data from Iranian National Cancer Registry between 2009 and 2014
    Briefland ; 2021
    In:  International Journal of Cancer Management Vol. 14, No. 5 ( 2021-06-15)
    Details
    In: International Journal of Cancer Management, Briefland, Vol. 14, No. 5 ( 2021-06-15)
    Abstract: Background: Sarcomas are a wide group of tumors with a mesenchymal origin, accounting for 1% of all adult malignancies. Objectives: This study examined the incidence rates and distribution patterns of morphological subtypes and primary sites of soft tissue and bone sarcomas in a 6-years period in the total population of Iran. Methods: The data was retrieved from the Iranian National Cancer Registry (INCR). A total of 14630 patients were identified with either bone or soft tissue sarcoma during 2009 - 2014. The morphological and topographical classifications were based on the ICD-O-3 and World Health Organization (WHO) guidelines. The crude and age-standardized incidence rates (ASIR) were calculated. Results: The combined crude incidence was calculated 3.2/100,000, and for STS and BS was 2.7 and 0.5 per 100,000 individuals, respectively, increasing with the age. Among the patients, 16.47 and 83.53% of cases had BS and STS, respectively with male predilection. The ASIR calculated 2.8 and 2.6 for STS and 0.51 and 0.37 for BS in males and females, respectively. Sarcoma, osteosarcoma, leiomyosarcoma, liposarcoma, and spindle cell sarcoma were the most common morphologies. The connective tissue of the lower limb, long bone of the lower limb, skin, and uterus were the most frequent primary tumor sites. The majority of tumors were of unknown/undifferentiated grade (grade 9), then grade 3, 1, 2, 4, and score 0 had the highest frequencies, respectively. The highest ASIR of sarcoma was detected in Khuzestan, Kohgiloyeh and Boyer-Ahmad, Isfahan, Tehran, Fars, and Khorasan Razavi provinces. Analysis of the incidence trends showed a slight increase over the study period. Conclusions: These findings can help better diagnose and management of sarcoma patients throughout Iran.
    Type of Medium: Online Resource
    ISSN: 2538-4422 , 2538-497X
    URL: Journal
    URL: Article
    DOI: 10.5812/ijcm
    DOI: 10.5812/ijcm.110504
    Language: Unknown
    Publisher: Briefland
    Publication Date: 2021
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  • 7
    Online Resource
    Online Resource
    Depth Analysis of Open Transhiatal Esophagectomy Outcomes (Orringer Technique) in Patients with Esophageal Cancer from 1990 to 2015: A 25-Year Experience Single-center Study
    Briefland ; 2023
    In:  International Journal of Cancer Management Vol. 16, No. 1 ( 2023-02-06)
    Details
    In: International Journal of Cancer Management, Briefland, Vol. 16, No. 1 ( 2023-02-06)
    Abstract: Background: Esophageal cancer is an invasive tumor with rapid growth and a poor prognosis. The annual incidence of esophageal cancer in the United States is 6 per 100 000 men and 1.6 per 100 000 women. This is different in the case of Iran, and the number of patients in the country is higher than in other countries. In this evaluation, the researchers present the experience with open Transhiatal Esophagectomy (Orringer) technique outcomes. Objectives: This study aimed at evaluating the Orringer technique and its complications in patients with esophageal cancer for 25 years at the Cancer Research Center of Shahid Beheshti University of Medical Sciences. Methods: This is a descriptive study conducted from the beginning of 1988 to 2016. In this study, 114 patients with a mean age of 55 years and a gender classification of 60% male and 40% female were evaluated. Results: After resection, more than 98% of patients were in the T3 N1 - N3 stage. There were 4 mortalities: 2 were due to descending aorta tearing, 1 was due to tracheobronchial tearing, and 1 was pneumonia From 40 cases of pleural effusion, only 5 cases (12.5%) needed a thoracotomy tube. Only 2 patients needed intervention from 30 patients with dysphagia; 1 case was relieved by balloon dilatation and the other needed a free jejunal flap. Five-year survivals were 30% and 20% versus 48% and 23% in the neoadjuvant and non-neoadjuvant groups, respectively. conclusions: The present study and other experiences showed that non-radical surgery such as the Orringer technique is acceptable and compassable compared to radical surgery in 3 fields.
    Type of Medium: Online Resource
    ISSN: 2538-4422 , 2538-497X
    URL: Journal
    URL: Article
    DOI: 10.5812/ijcm
    DOI: 10.5812/ijcm-107922
    Language: Unknown
    Publisher: Briefland
    Publication Date: 2023
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  • 8
    Online Resource
    Online Resource
    Melanoma in Iranian Childhood and Adolescence: An Analysis of 14 Patients
    Briefland ; 2023
    In:  International Journal of Cancer Management Vol. 16, No. 1 ( 2023-03-10)
    Details
    In: International Journal of Cancer Management, Briefland, Vol. 16, No. 1 ( 2023-03-10)
    Abstract: Background: Skin cancer is the most common cancer in Iran. Given the importance of early diagnosis in treating early tumors, knowledge of the demographic and pathological findings of the disease is helpful. Objectives: The aim of present study was to investigate the incidence, trend and risk factors of melanoma in Iranian childhood and adolescents. Methods: The present retrospective study was performed between 2005 and 2014 on registered data in the National Cancer Registry System, Iran. The age group studied was patients 18 years or younger. Data included demographic status, risk factors, clinical and histopathological characteristics. Results: The results showed that 8 (57.1%) of 14 patients were males. The mean age of the study population was 8.71 ± 6.02 years (range, 1 - 15 years). Ten (71.4%) patients were of Fars ethnic groups. In terms of tumor invasiveness, 13 (92.9%) patients were invasive and one (7.1%) patient was in situ. The growth phase of melanoma was vertical in 13 (92.9%) patients and radial phase in one (7.1%) patient. In terms of lymph node metastasis, it was observed in only one patient. Surgical treatment was performed on all patients. Melanoma histology was nodular in 3 patients and unspecified or unregistered in the rest. The most area of the tumor was in the head/neck and lower limbs. Conclusions: According to the results, regardless of the differences in the specific coverage of the Iranian people, the distribution and statistical characteristics of malignant melanoma in Iran are almost similar to other countries in the world. Further studies are recommended to confirm the findings of the present study.
    Type of Medium: Online Resource
    ISSN: 2538-4422 , 2538-497X
    URL: Journal
    URL: Article
    DOI: 10.5812/ijcm
    DOI: 10.5812/ijcm-121873
    Language: Unknown
    Publisher: Briefland
    Publication Date: 2023
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  • 9
    Online Resource
    Online Resource
    Comparison of the Effects of Hypothermia and Normothermia on Cognitive Functions After Coronary Artery Bypass Surgery
    Briefland ; 2021
    In:  Multidisciplinary Cardiovascular Annals Vol. 12, No. 2 ( 2021-04-10)
    Details
    In: Multidisciplinary Cardiovascular Annals, Briefland, Vol. 12, No. 2 ( 2021-04-10)
    Abstract: Background: Cognitive impairment is among the most prevalent complications in patients undergoing CABG. Selection of the proper temperature is one of the main moderating factors in cognitive impairment following CABG. Today, heart surgery is done using the two methods of hypothermia and normothermia. However, there is no consensus over the method with the least side effects. Objectives: This study aims to compare the effects of hypothermia and normothermia on cognitive functions after undergoing CABG during the hospitalization period. Methods: A total of 130 patients in this cohort observational study were divided into two groups of normothermic (n = 65) and hypothermic (n = 65). In the hypothermic group, the temperature was down to 32°C, and in the normothermic group, the temperature decreased to 35°C. After the surgery and transferring the patients to the ICU, demographic information and MMSE questionnaires were completed from the second to the sixth day at the same time. Results: The results showed no significant differences between the two groups in educational and social demographic characteristics (P 〉 0.05). Besides, there was no significant differences between the two groups in the history of the disease (P = 1.000). In addition, there was no significant relationship between cognitive performance scores of the two groups before the surgery (P = 1.000). However, there was a significant relationship between the two groups from the second (P = 0.003), third (P = 0.000) and the fourth day (P = 0.023) after the surgery. In the normothermic group, on the second, as well as third and fourth days 14 and 9 patients suffered from cognitive impairment, respectively. Besides, in the hypothermic group, on the second, third, and fourth days after surgery, 28, 30, and 23 patients suffered from cognitive impairment, respectively. However, there was no significant relationship between the two groups on the fifth and sixth days after the surgery (P = 0.079). Conclusions: The present study showed that during hospitalization after undergoing CABG, cognitive impairment in patients with the normothermic method was less severe than that in patients with the hypothermic method. Besides, clinical outcomes were more satisfactory in the former group.
    Type of Medium: Online Resource
    ISSN: 2538-5550
    URL: Journal
    URL: Article
    DOI: 10.5812/mca
    DOI: 10.5812/mca.111442
    Language: Unknown
    Publisher: Briefland
    Publication Date: 2021
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  • 10
    Online Resource
    Online Resource
    Effect of Cold Hemodialysis on Hemoglobin and Hematocrit in Hemodialysis Patients: A Crossover Clinical Trial Study
    Briefland ; 2019
    In:  Medical - Surgical Nursing Journal Vol. 8, No. 2 ( 2019-06-24)
    Details
    In: Medical - Surgical Nursing Journal, Briefland, Vol. 8, No. 2 ( 2019-06-24)
    Type of Medium: Online Resource
    ISSN: 2322-178X , 2322-4169
    URL: Journal
    URL: Article
    DOI: 10.5812/msnj
    DOI: 10.5812/msnj.95478
    Language: Unknown
    Publisher: Briefland
    Publication Date: 2019
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