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  • 1
    UID:
    edoccha_BV036069276
    Format: 1 Online-Ressource (X, 212 Seiten) : , Illustrationen, Diagramme.
    ISBN: 978-3-318-01006-0
    Series Statement: Monographs in virology Vol. 24
    Content: Cytomegalovirus (CMV) infection causes severe diseases in immunocompromised patients. CMV-related morbidity is frequently linked to aberrant immune responses occurring locally within the respective tissues including immune-privileged sites such as the retina. There is growing evidence that CMV-related pathomechanisms differ profoundly as a function of cell type and differentiation state of the host cell.This book provides important new insights into CMV-related immunopathology, discusses molecular mechanisms involved in HCMV-mediated tissue injury, CMV latency and reactivation, and presents novel ideas and concepts to develop alternative antiviral drugs. As an important focus, the role of CMV-reactive T cells in protection, pathogenesis, diagnosis and therapy of HCMV infection is discussed.The contributions to this book are written by leading scientists and clinicians in the field of CMV who participated in the fourth international meeting on CMV-related immunopathology, held in Berlin, September 2002. Comprehensive and up-to-date, this volume is a vital reference for clinicians involved in the diagnosis and treatment of CMV infections, as well as for researchers working in the field of herpesvirus biology and the development of antiviral drugs
    Note: 4th Symposium, Berlin, September 2002
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-7618-5
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Cytomegalie ; Infektion ; Immunpathologie ; Konferenzschrift
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    UID:
    almahu_BV036069276
    Format: 1 Online-Ressource (X, 212 Seiten) : , Illustrationen, Diagramme.
    ISBN: 978-3-318-01006-0
    Series Statement: Monographs in virology Vol. 24
    Content: Cytomegalovirus (CMV) infection causes severe diseases in immunocompromised patients. CMV-related morbidity is frequently linked to aberrant immune responses occurring locally within the respective tissues including immune-privileged sites such as the retina. There is growing evidence that CMV-related pathomechanisms differ profoundly as a function of cell type and differentiation state of the host cell.This book provides important new insights into CMV-related immunopathology, discusses molecular mechanisms involved in HCMV-mediated tissue injury, CMV latency and reactivation, and presents novel ideas and concepts to develop alternative antiviral drugs. As an important focus, the role of CMV-reactive T cells in protection, pathogenesis, diagnosis and therapy of HCMV infection is discussed.The contributions to this book are written by leading scientists and clinicians in the field of CMV who participated in the fourth international meeting on CMV-related immunopathology, held in Berlin, September 2002. Comprehensive and up-to-date, this volume is a vital reference for clinicians involved in the diagnosis and treatment of CMV infections, as well as for researchers working in the field of herpesvirus biology and the development of antiviral drugs
    Note: 4th Symposium, Berlin, September 2002
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-7618-5
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Cytomegalie ; Infektion ; Immunpathologie ; Konferenzschrift
    Library Location Call Number Volume/Issue/Year Availability
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  • 3
    UID:
    almafu_BV036069070
    Format: 1 Online-Ressource (XII, 308 Seiten) : , Illustrationen, Diagramme.
    ISBN: 978-3-318-00262-1
    Series Statement: Monographs in virology Vol. 21
    Content: Cytomegalovirus (CMV) infection can cause severe diseases with significant morbidity and mortality in immunocompromised patients such as bone marrow or solid-organ transplant recipients, and AIDS patients. Major manifestations include transplant rejection, hepatitis, pneumonitis, encephalitis and retinitis. There is growing evidence that in certain cases CMV disease is closely linked to aberrant immune responses occurring locally within the respective tissues.This book provides important new insights into CMV-related immunopathology, discusses current methods of CMV diagnosis and anti-CMV therapy, and proposes novel antiviral treatment strategies. It contains contributions by leading scientists and clinicians in the field of CMV, who participated in the 'First International Round Table Consensus Meeting', held in Frankfurt, Germany, in August 1997. Comprehensive and up-to-date, this volume is a vital reference for clinicians involved in the diagnosis and treatment of CMV infections, as well as for researchers working on herpesvirus biology and the development of antiviral drugs
    Note: 1st International Consensus Round Table Meeting, Frankfurt, August 1997 ; expert reviews on current and future anti-CMV treatment strategies
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-6602-5
    Language: English
    Subjects: Medicine
    RVK:
    RVK:
    Keywords: Cytomegalie-Virus ; Infektion ; Immunpathologie ; Cytomegalie ; Konferenzschrift
    Author information: Doerr, Hans Wilhelm 1945-
    Author information: Rabenau, Holger
    Library Location Call Number Volume/Issue/Year Availability
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  • 4
    UID:
    edoccha_BV036069070
    Format: 1 Online-Ressource (XII, 308 Seiten) : , Illustrationen, Diagramme.
    ISBN: 978-3-318-00262-1
    Series Statement: Monographs in virology Vol. 21
    Content: Cytomegalovirus (CMV) infection can cause severe diseases with significant morbidity and mortality in immunocompromised patients such as bone marrow or solid-organ transplant recipients, and AIDS patients. Major manifestations include transplant rejection, hepatitis, pneumonitis, encephalitis and retinitis. There is growing evidence that in certain cases CMV disease is closely linked to aberrant immune responses occurring locally within the respective tissues.This book provides important new insights into CMV-related immunopathology, discusses current methods of CMV diagnosis and anti-CMV therapy, and proposes novel antiviral treatment strategies. It contains contributions by leading scientists and clinicians in the field of CMV, who participated in the 'First International Round Table Consensus Meeting', held in Frankfurt, Germany, in August 1997. Comprehensive and up-to-date, this volume is a vital reference for clinicians involved in the diagnosis and treatment of CMV infections, as well as for researchers working on herpesvirus biology and the development of antiviral drugs
    Note: 1st International Consensus Round Table Meeting, Frankfurt, August 1997 ; expert reviews on current and future anti-CMV treatment strategies
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-6602-5
    Language: English
    Subjects: Medicine
    RVK:
    RVK:
    Keywords: Cytomegalie-Virus ; Infektion ; Immunpathologie ; Cytomegalie ; Konferenzschrift
    Author information: Doerr, Hans Wilhelm 1945-
    Author information: Rabenau, Holger
    Library Location Call Number Volume/Issue/Year Availability
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  • 5
    UID:
    almafu_BV011802724
    Format: XII, 308 S. : graph. Darst.
    ISBN: 3-8055-6602-6
    Series Statement: Monographs in virology 21
    Note: Literaturangaben
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Cytomegalie-Virus ; Infektion ; Immunpathologie ; Cytomegalie ; Konferenzschrift ; Congress ; Konferenzschrift ; Konferenzschrift
    Library Location Call Number Volume/Issue/Year Availability
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  • 6
    UID:
    edocfu_9958103963502883
    Format: 1 online resource (222 p.)
    ISBN: 3-318-01006-5
    Series Statement: Monographs in virology, v. 24
    Content: Cytomegalovirus (CMV) infection causes severe diseases in immunocompromised patients. CMV-related morbidity is frequently linked to aberrant immune responses occurring locally within the respective tissues including immune-privileged sites such as the retina. There is growing evidence that CMV-related pathomechanisms differ profoundly as a function of cell type and differentiation state of the host cell. This book provides important new insights into CMV-related immunopathology, discusses molecular mechanisms involved in HCMV-mediated tissue injury, CMV latency and reactivation, and presents novel ideas and concepts to develop alternative antiviral drugs. As an important focus, the role of CMV-reactive T cells in protection, pathogenesis, diagnosis and therapy of HCMV infection is discussed. The contributions to this book are written by leading scientists and clinicians in the field of CMV who participated in the fourth international meeting on CMV-related immunopathology, held in Berlin, September 2002. Comprehensive and up-to-date, this volume is a vital reference for clinicians involved in the diagnosis and treatment of CMV infections, as well as for researchers working in the field of herpesvirus biology and the development of antiviral drugs.
    Note: Description based upon print version of record. , ""Contents""; ""Preface""; ""The Endothelium as a Mediator of CMV-Associated Immunopathology""; ""Effect of CMV Infection on Chronic Rejection of Kidney Transplants""; ""CMV and Atherosclerosis""; ""Human Cytomegalovirus in Immune Privileged Sites: HCMV Retinitis and the Role of NF-kB""; ""Transmission of Cytomegalovirus to Preterm Infants by Breast-Feeding""; ""Human Cytomegalovirus Escapes Cell-Mediated Immune Responses""; ""Counteraction of Interferon-Induced Antiviral Responses by Cytomegalovirus""; ""Mechanisms of Immunodominance in Human Cytomegalovirus Infection"" , ""HCMV Latency and Lytic Gene Regulation: A Question of Chromatin Structure?""""Taking Away the Replication License � HCMV and Its Impact on Cellular DNA Synthesis""; ""Interactions and Functions of Human Cytomegalovirus Tegument Proteins""; ""Measuring T-Cell Reactivity to Cytomegalovirus: State of the Art""; ""Measurement of CMV DNA Levels and CMV-Specific CD4 + Lymphocyte Counts in Patient Specimens: Requirements for Test Quality and Practicability in a Routine Diagnostic Service""; ""Manipulation of CMV-Specific Immune Responses following Stem Cell Transplantation"" , ""Fast Genotypic Identification and Estimation of Ganciclovir-Resistant Cytomegalovirus from Clinical Specimens""""Non-Nucleoside Inhibitors of HCMV Replication""; ""New Concepts for Inhibition of HCMV Reactivation and Replication""; ""CMV Vaccines to Prevent Congenital Infection""; ""Subject Index"" , English
    Additional Edition: ISBN 3-8055-7618-8
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 7
    UID:
    edoccha_9958103988102883
    Format: 1 online resource (321 p.)
    ISBN: 3-318-00262-3
    Series Statement: Monographs in virology ; 21
    Content: Cytomegalovirus (CMV) infection can cause severe diseases with significant morbidity and mortality in immunocompromised patients such as bone marrow or solid-organ transplant recipients, and AIDS patients. Major manifestations include transplant rejection, hepatitis, pneumonitis, encephalitis and retinitis. There is growing evidence that in certain cases CMV disease is closely linked to aberrant immune responses occurring locally within the respective tissues. This book provides important new insights into CMV-related immunopathology, discusses current methods of CMV diagnosis and anti-CMV therapy, and proposes novel antiviral treatment strategies. It contains contributions by leading scientists and clinicians in the field of CMV, who participated in the ‘First International Round Table Consensus Meeting’, held in Frankfurt, Germany, in August 1997. Comprehensive and up-to-date, this volume is a vital reference for clinicians involved in the diagnosis and treatment of CMV infections, as well as for researchers working on herpesvirus biology and the development of antiviral drugs.
    Note: Description based upon print version of record. , ""Contents""; ""Preface""; ""Patronage of the Meeting""; ""Sponsors""; ""Acknowledgements""; ""Cytomegalovirus Persistence: Escape from Cell-Mediated Immunosurveillance""; ""Mechanisms of Immunosuppression by Human Cytomegalovirus""; ""Human Cytomegalovirus Infection in Transplant Recipients: Role of TNF-a for Reactivation and Replication of Human Cytomegalovirus""; ""Pathogenesis of Murine Cytomegalovirus Infection in Neonatal Mice""; ""Cytomegalovirus as a Perturbing Factor in Graft/Host Equilibrium: Havoc at the Endothelial Interface"" , ""Current Antiviral Therapy Fails to Prevent the Pro-Inflammatory Effects of Cytomegalovirus Infection,Whilst Rendering Infected Cells Relatively Resistant to Immune Attack""""Cytomegalovirus, Oxidative Stress and Inflammation as Interdependent Pathomechanisms: Need for Novel Therapeutic Strategies?""; ""Cytomegalovirus Infection following Hematopoietic Stem Cell Transplantation""; ""Cytomegalovirus Pathogenesis after Experimental Bone Marrow Transplantation"" , ""Two Types of Cytomegalovirus-Specific Memory Responses: Potential Role of Donor Infected Target Cells in Recruitment of Activated T Cells to the Graft1""""Role of Cytomegalovirus Infection in the Processes of Organ Allograft Rejection""; ""Role of Cytomegalovirus Infection in Transplant Arteriosclerosis""; ""CMV Retinitis: Clinical Experience with theMetal Chelator Desferrioxamine""; ""Drug Resistance and the UL97 Gene of Human Cytomegalovirus""; ""Antiviral Agents That Are Active against CMV: Potential of Cidofovir for the Treatment of CMV and Other Virus Infections"" , ""Cidofovir, a New Addition to the Available Therapies against Cytomegalovirus""""New Anti-CMV Strategies""; ""Immunomodulation with Intravenous Immunoglobulins in the Treatment of Cytomegalovirus-Associated Immunopathology and Autoimmune Diseases""; ""Analytical Performance of a Quantitative CMV DNA DetectionMethod""; ""Relationship between Monitoring the Viral Load in Blood, Human Cytomegalovirus Pathophysiology and Management Strategies of Patients after Transplantation""; ""Quantitative Cytomegalovirus Detection"" , ""Relative Importance of Cytomegalovirus Load as a Risk Factor for Cytomegalovirus Disease in the Immunocompromised Host""""Author Index""; ""Subject Index"" , English
    Additional Edition: ISBN 3-8055-6602-6
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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