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Format: Online-Ressource

Edition: 2012

Edition: Online-Ausg. Springer eBook Collection. Biomedical and Life Sciences

ISBN: 9781461415664

Series Statement: Advances in Experimental Medicine and Biology 737

Content: Davi

Additional Edition: ISBN 9781461415657

Language: English

Subjects: Biology

Keywords: Sauerstoffversorgung

DOI: 10.1007/978-1-4614-1566-4

URL: Volltext

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Format: Online-Ressource (XXX, 368p. 120 illus, digital)

ISBN: 9781441977564

Series Statement: Advances in Experimental Medicine and Biology 701

Content: This book covers all aspects of oxygen delivery to tissue, including blood flow and its regulation as well as oxygen metabolism. Special attention will be paid to methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. This book is multidisciplinary and designed to bring together experts and students from a range of research fields including biochemical engineering, physiology, microcirculation, and hematology.

Content: This book covers all aspects of oxygen delivery to tissue, including blood flow and its regulation as well as oxygen metabolism. Special attention will be paid to methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. This book is multidisciplinary and designed to bring together experts and students from a range of research fields including biochemical engineering, physiology, microcirculation, and hematology

Note: Includes bibliographical references and indexes , Oxygen Transport to Tissue XXXII; Editors; Acknowledgments; Preface; Contents; Part I Near Infrared Spectroscopy; Chapter 1 The Western Reserve, Edward Morley, and Oxygen; A Brief Historical Introduction; 1.1 Introduction; 1.2 The Western Reserve of Connecticut; 1.3 Edward Williams Morley (1838-1923); 1.4 The Composition of the Atmosphere (1879-1882); 1.5 The Michelson-Morley Collaboration (1884-1887); 1.6 The AtomicWeight of Oxygen (1884-1895); 1.7 The Rest of the Story; References , Chapter 2 Analysis of the Changes in the Oxidation of Brain Tissue Cytochrome-c-Oxidase in Traumatic Brain Injury Patients during HypercapnoeaA Broadband NIRS Study; 2.1 Introduction; 2.2 Methods; 2.3 Results; 2.4 Discussion; Acknowledgments; References; Chapter 3 Effects of Assuming Constant Optical Scattering on Haemoglobin Concentration Measurements Using NIRS during a Valsalva Manoeuvre; 3.1 Introduction; 3.2 Methods; 3.3 Analysis; 3.4 Results; 3.5 Discussion; Acknowledgments; References , Chapter 4 Speech Therapy Changes Blood Circulation and Oxygenation in the Brain and Muscle A Near-Infrared Spectrophotometry Study4.1 Introduction; 4.2 Methods; 4.3 Results; 4.4 Discussion; 4.5 Conclusion; Acknowledgments; References; Part II Oxygen Sensors and Measurement; Chapter 5 Evaluation of Lithium Naphthalocyanine (LiNc) Microcrystals for Biological EPR Oximetry; 5.1 Introduction; 5.2 Materials and Methods; 5.2.1 Preparation of particulates for cell culture studies; 5.2.2 Z-stack localization studies of nanocrystalline LiNc in cells; 5.2.3 Preparation of mice , 5.2.4 pO2 measurements in gastrocnemius muscle tissue of mice5.3 Results; 5.3.1 Oxygen-sensitivity of LiNc probes; 5.3.2 Evaluation of LiNc for in vivo oximetry; 5.3.3 Endocytosis of LiNc by MSCs; 5.4 Discussion; 5.4.1 Conclusions; Acknowledgments; References; Chapter 6 Challenges to Intestinal pO2 Measurement Using EPR; 6.1 Introduction; 6.2 Methods; 6.2.1 Animal Preparation; 6.2.2 Probe Placement and EPR Measurement; 6.2.3 Statistical Methods; 6.3 Results; 6.4 Discussion and Conclusions; Acknowledgments; References , Chapter 7 Quantification of Systemic Interference in Optical Topography Data during Frontal Lobe and Motor Cortex Activation: An Independent Component Analysis7.1 Introduction; 7.2 Methods; 7.3 Results; 7.4 Discussion; Acknowledgments; References; Chapter 8 Measuring Oxygen in Living Tissue: Intravascular, Interstitial, and "Tissue" Oxygen Measurements; 8.1 Introduction; 8.2 Materials and Methods; 8.3 Results and Discussion; 8.4 Conclusions; Acknowledgments; References , Chapter 9 Cerebral Oxygenation of the Cortex and Striatum Following Normobaric Hyperoxia and Mild Hypoxia in Rats by EPR Oximetry Using Multi-Probe Implantable Resonators

Additional Edition: ISBN 9781441977557

Additional Edition: Buchausg. u.d.T. ISBN 978-1-441-97755-7

Language: English

Subjects: Biology

DOI: 10.1007/978-1-4419-7756-4

URL: Volltext

URL: Volltext  (lizenzpflichtig)

URL: Einführung/Vorwort

URL: Inhaltsverzeichnis

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Format: Online-Ressource , digital

Edition: Springer eBook Collection. Biomedical and Life Sciences

ISBN: 9781461449898

Series Statement: Advances in Experimental Medicine and Biology 765

Content: From the 39th annual conference of the International Society on Oxygen Transport to Tissue (ISOTT), held in Washington, DC, USA in July 2011, this volume covers aspects of oxygen transport from air to the cells, organs and organisms; instrumentation and methods to sense oxygen and clinical evidence. Oxygen Transport to Tissue XXXIV includes contributions from scientists (physicists, biologists and chemists), engineers, clinicians and mathematicians.

Content: From the 39th annual conference of the International Society on Oxygen Transport to Tissue (ISOTT), held in Washington, DC, USA in July 2011, this volume covers aspects of oxygen transport from air to the cells, organs and organisms; instrumentation and methods to sense oxygen and clinical evidence. Oxygen Transport to Tissue XXXIV includes contributions from scientists (physicists, biologists and chemists), engineers, clinicians and mathematicians

Note: Description based upon print version of record , Oxygen Transport to Tissue XXXIV; Dedication: Britton Chance, M.D., Ph.D., D.Sc.; Abstract; Selected Photos of Dr. Chance; The Life, Times and Legacy of Dr. Chance in Science; Education; Honorary Degrees; Academic Career; Postgraduate Training and Fellowship Appointments; Special Appointments; Awards and Honors; Elections to Honorary Societies; Short Summary of Scienti fi c Contributions; Copyright Acknowledgement; References; Preface; Acknowledgements; Sponsors; Organization ISOTT 2011; Organizing Committee; ISOTT Of fi cers and Executive Committee; Awards; The Melvin H. Knisely Award , The Dietrich W. Lübbers AwardThe Britton Chance Award; The Duane F. Bruley Travel Awards; Contents; Contributors; Reviewers; Chapter 1: Effects of Experimentally Deviated Mandibular Position on Stress Response; 1 Introduction; 2 Materials and Methods; 3 Results; 4 Discussion; 5 Conclusions; References; Chapter 2: Kidney EPO Expression During Chronic Hypoxia in Aged Mice; 1 Introduction; 2 Methods; 2.1 Exposure to Chronic Hypobaric Hypoxia; 2.2 Tissue Collection and Preparation of Whole Cell Lysates; 2.3 Western Blot Analysis; 2.4 Statistical Analysis; 3 Results; 4 Discussion; References , Chapter 3: Nature's "Silver Bullet" for Anticoagulation: Mechanism of Zymogen Protein C to Activated Protein C1 Introduction; 2 The ZPC to APC Process and APC Function; 3 ZPC Production; 4 Conclusion; References; Chapter 4: Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO; 1 Introduction; 2 Methods; 3 Results; 4 Discussion; References; Chapter 5: Blood Oxygen Level Dependent Magnetization Transfer (BOLDMT) Effect; 1 Introduction; 2 Methods; 3 Results; 4 Discussions; References , Chapter 6: Characterizing Prostate Tumor Mouse Xenografts with CEST and MT-MRI and Redox Scanning1 Introduction; 2 Methods; 3 Results; 4 Discussion and Conclusions; References; Chapter 7: In Vitro Sirius Red Collagen Assay Measures the Pattern Shift from Soluble to Deposited Collagen; 1 Introduction; 2 Methods; 3 Results; 4 Discussion; 5 Conclusion; References; Chapter 8: Intravoxel Incoherent Motion MR Imaging of the Kidney: Pilot Study; 1 Introduction; 2 Methods; 3 Results; 4 Discussion; References , Chapter 9: Changes in Gastric Mucosa, Submucosa, and Muscularis IC pH May Herald Irreversible Tissue Injury1 Introduction; 2 Methods; 2.1 Animal Preparation; 2.2 Study Models; 2.3 IC pH Analysis; 2.4 Data Analysis; 3 Results; 4 Conclusion; References; Chapter 10: Normobaric Hyperoxia Does Not Change Optical Scattering or Pathlength but Does Increase Oxidised Cytochrome c Oxidase Concentration in Patients with Brain Injury; 1 Introduction; 2 Methods; 3 Results; 4 Discussion; References , Chapter 11: Multi-frequency Forced Oscillation Technique Using Impulse Oscillations: Can It Give Mechanical Information about the Lung Periphery?

Additional Edition: ISBN 9781461447719

Additional Edition: Print version Oxygen Transport to Tissue XXXIV

Language: English

Subjects: Biology

Keywords: Sauerstoffversorgung

DOI: 10.1007/978-1-4614-4989-8

URL: Volltext  (lizenzpflichtig)

UID:

Format: Online-Ressource (XXX, 507 Seiten) , Illustrationen

Edition: Springer eBook Collection. Biomedical and Life Sciences

ISBN: 9781461474111

Series Statement: Advances in Experimental Medicine and Biology Volume 789

Content: From the 40th annual conference of the International Society on Oxygen Transport to Tissue (ISOTT), held in Bruges, Belgium in August 2012, this volume covers aspects of clinical applications, muscle oxygenation, cancer, measurement technologies, oxygen transport modelling and Near-Infrared Spectroscopy (NIRS), cell metabolism and brain oxygenation. Each topic was presented by one or two invited speakers, and a series of contributed talks

Note: Description based upon print version of record , Preface; Acknowledgements; Industrial Sponsors; Academic Sponsors; Organization ISOTT 2012; Local Organizing Committee; Scientific Committee; ISOTT Officers and Executive Committee; Newly Elected Members of the Executive Committee; Awards; The Melvin H. Knisely Award; Melvin H. Knisely Award Recipients; The Dietrich W. Lübbers Award; Dietrich W. Lübbers Award Recipients; The Britton Chance Award; Britton Chance Award Recipients; The Duane F. Bruley Travel Award; Duane F. Bruley Travel Award Recipients; Kovach Lecture; Kovach Lecture Recipients; Contents; Contributors; Reviewers , Technical ReviewersChapter 1: Remembering Professor Mamoru Tamura; 1.1 Dr. Mamoru Tamura's Scientific Achievements and Contributions to the Society; References; Hypoxia; Chapter 2: Increased Kidney Metabolism as a Pathway to Kidney Tissue Hypoxia and Damage: Effects of Triiodothyronine and Dinitrophenol in Normoglycemic Rats; 2.1 Introduction; 2.2 Materials and Methods; 2.3 Results; 2.4 Discussion; References; Chapter 3: Hypoxia-Induced Cerebral Angiogenesis in Mouse Cortex with Two-Photon Microscopy; 3.1 Introduction; 3.2 Materials and Methods; 3.2.1 Animal Preparation , 3.2.2 Imaging Experiment3.3 Results and Discussion; 3.4 Conclusions; References; Chapter 4: Reduction of Cytochrome c Oxidase During Vasovagal Hypoxia-Ischemia in Human Adult Brain: A Case Study; 4.1 Introduction; 4.2 Methods; 4.3 Results; 4.4 Discussion; References; Chapter 5: Increased HIF-1α and HIF-2α Accumulation, but Decreased Microvascular Density, in Chronic Hyperoxia and Hypercapnia in the Mouse Cerebral Cortex; 5.1 Introduction; 5.2 Experimental Procedures; 5.2.1 Exposure to Chronic Hyperoxia with Hypercapnia and Measurement of Blood Gas Content , 5.2.2 Preparation of Whole Cell Lysates and Western Blot Analysis5.2.3 IHC and Determination of the Capillary Density; 5.3 Results; 5.3.1 HIF-1α and HIF-2α Protein Accumulation and VEGF and Flk-1 Expression in the Brain; 5.3.2 PGC-1α, EPO, COX-2, and Ang-2 Protein Expression; 5.3.3 Capillary Density in the Cerebral Cortex and Arterial Blood Gas Content; 5.4 Discussion; References; Chapter 6: Oxygen Delivery: The Principal Role of the Circulation; 6.1 Introduction; 6.2 Evidence for Constancy of the DO 2 :VO 2 Ratio; 6.3 Examples of Major Organ Constancy of the DO 2 :VO 2 Ratio , 6.3.1 Whole Body and Exercising Skeletal Muscle6.3.2 Cerebral Autoregulation of Blood Flow and DO 2; 6.3.3 Coronary Arterial Oxygen Delivery to the Heart; 6.3.4 General Summary; 6.4 Examples of Whole Body Constancy of the DO 2 :VO 2 Ratio; 6.4.1 Exposure to 12 % Oxygen Inspirate; 6.4.2 Longer-Term (Altitude) Hypoxia; 6.4.3 Periodic Breathing with Oscillating Cardiac Output; 6.5 Conclusions; References; Chapter 7: Heart Rate Variability in Newborns with Hypoxic Brain Injury; 7.1 Introduction; 7.2 Dataset; 7.3 Methods; 7.4 Results; 7.5 Discussion; References; Brain Oxygenation , Chapter 8: Simultaneous Monitoring of Brain and Skin Oxygenation During Haemorrhagic Shock in Piglets , PrefaceAcknowledgements -- Remembering Professor Mamoru Tamura -- Part 1: Hypoxia -- Increased Kidney Metabolism as a Pathway to Kidney Tissue Hypoxia and Damage: Effects of Triiodothyronine and Dinitrophenol in Normoglycemic Rats -- Hypoxia-Induced Cerebral Angiogenesis in Mouse Cortex with Two-Photon Microscopy -- Reduction of Cytochrome c Oxidase During Vasovagal Hypoxia-Ischaemia in Human Adult Brain: A Case Study -- Increased HIF-1α and 2α Accumulation, but Decreased Microvascular Density, in Chronic Hyperoxia and Hypercapnia in the Mouse Cerebral Cortex -- Oxygen Delivery: The Principal Role of the Circulation -- Heart Rate Variability in Newborns with Hypoxic Brain Injury -- Part 2: Brain Oxygenation -- Simultaneous Monitoring of Brain and Skin Oxygenation during Haemorrhagic Shock in Piglets -- Hemispheric Differences of Motor Execution:  A Near-Infrared Spectroscopy Study -- Acute Stress Exposure Preceding Global Brain Ischemia Accelerates Decreased Doublecortin Expression in the Rat Retrosplenial Cortex -- Effects of Transcranial Direct Current Stimulation of the Motor Cortex on Prefrontal Cortex Activation during a Neuromuscular Fatigue Task: An fNIRS Study -- The Effect of Inner Speech on Arterial CO2, Cerebral Hemodynamics and Oxygenation - A Functional NIRS Study -- Investigation of Frontal Lobe Activation with fNIRS and Systemic Changes during Video Gaming -- Effect of Valsalva Maneuver-induced Hemodynamic Changes on Brain Near-infrared Spectroscopy Measurements -- Cerebral Autoregulation in Premature Infants -- Brain Tissue Oxygen Saturation Increases during Sleep in Adolescents -- Changes of Cerebral Oxygen Metabolism and Hemodynamics during ECPR with Hypothermia Measured by Near Infrared Spectroscopy: A Pilot Study -- Part 3: Muscle Oxygenation -- Analysis of NIRS-based Muscle Oxygenation Parameters by Inclusion of Adipose Tissue Thickness -- Statistical Treatment of Oxygenation-related Data in Muscle Tissue -- O2 Saturation in the Intercostal Space during Moderate and Heavy Constant-load Exercise -- Muscle, Prefrontal and Motor Cortex Oxygenation Profiles during Prolonged Fatiguing Exercise -- Aging Affects Spatial Distribution of Leg Muscle Oxygen Saturation during Ramp Cycling Exercise -- Which is the Best Indicator of Muscle Oxygen Extraction during Exercise using NIRS?  - Evidence that HHb is not the Candidate -- Tissue Oxygenation during Exercise Measured with NIRS: Reproducibility and Influence of Wavelengths -- Using Portable NIRS to Compare Arm and Leg Muscle Oxygenation during Roller-skiing in Bi-athletes: A Case Study -- The Use of Portable NIRS to measure Muscle Oxygenation and Haemodynamics during a Repeated Sprint Running Test -- Tumor Oxygenation -- Amifostine Acts upon Mitochondria to Stimulate Growth of Bone Marrow and Regulate Cytokines -- Hypoxia, Lactate Accumulation and Acidosis: Siblings Or Accomplices Driving Tumor Progression And Resistance To Therapy? -- Breast Cancer Detection of Large Size to DCIS by Hypoxia and Angiogenesis using NIRS -- Impact of Extracellular Acidosis on Intracellular pH Control and Cell Signaling in Tumor Cells -- Tumor Oxygenation: An Appraisal of Past and Present Concepts, and a Look into the Future -- In Vivo Metabolic Evaluation of Breast Tumor Mouse Xenografts for Predicting Aggressiveness Using the Hyperpolarized 13C-NMR Technique -- Mapping the Redox State of CHOP-treated Non-Hodgkin’s Lymphoma Xenografts in Mice -- Maternal Bias in Mouse Radiosensitivity: The Role of the Mitochondrial PTP -- Interleukin 11 Protects Bone Marrow Mitochondria from Radiation Damage -- Tumor Reoxygenation following Administration of the EGFR inhibitor, Gefitinib, in Experimental Tumors -- Radiation Affects the Responsiveness of Bone Marrow to G-CSF -- Application of MOBILE (Mapping of Oxygen By Imaging Lipids relaxation Enhancement) to Study Variations in Tumor Oxygenation -- Primo Vascular System and its Potential Role in Cancer Metastasis -- Part 5: Cell Metabolism -- Pancreaticoduodenectomy using Perioperative Zymogen Protein C to Help Prevent Blood Clotting.  A Trilogy on Increased Patient Safety -- Inhibition of Mammalian Target of Rapamycin Induces Renal Mitochondrial Uncoupling in Rats -- Molecular Hydrogen Consumption in the Human Body during the Inhalation of Hydrogen Gas -- Oxidative Metabolism: Glucose vs Ketones -- Part 6: System Modelling -- Modelling Blood Flow and Metabolism in the Piglet Brain during Hypoxia-ischaemia: Simulating pH Changes -- Modelling Blood Flow and Metabolism in the Piglet Brain during Hypoxic-ischaemia: Simulating Brain Energetics -- Mathematical Modelling of Near Infrared Spectroscopy Signals and Intracranial Pressure in Brain Injured Patients -- Dependence on NIRS Source-Detector Spacing of Cytochrome C Oxidase Response to Hypoxia and Hypercapnia in the Adult Brain -- Modeling Hemoglobin Nitrite Reductase Activity as a Mechanism of Hypoxic Vasodilation? -- Part 7: Measurement Technologies -- Development of a Hybrid Microwave-optical Tissue Oxygenation Probe to Measure Thermal Response in the Deep Tissue -- Oxygen Sensitive Quantum Dots for Possible Nano-scale Oxygen Imaging in Cultured Cells -- Boron Tracedrug Design for Neutron Dynamic Therapeutics for LDL -- New Method of Analysing NIRS Data from Prefrontal Cortex at Rest -- Radiation Oxygen Biology with Pulse Electron Paramagnetic Resonance Imaging in Animal Tumors -- Wavelength Selection for the Improvement of the Signal to Noise Ratio for Imaging of Haemoglobin Oxygenation with RGB Reflectometry -- Improving Pulse Oximetry Accuracy by Removing Motion Artifacts from Photoplethysmograms using Relative Sensor Motion: A Preliminary Study -- Measuring the Vascular Diameter of Brain Sur-face and Parenchymal Arteries in Awake Mouse -- Simultaneous Imaging of Cortical Blood Flow and Haemoglobin Concentration with LASCA and RGB Reflectometry -- Quality Evaluation Method for Rat Brain Cryofixation Based on NADH Fluorescence -- Cerebral Cortex Activation Mapping upon Electrical Muscle Stimulation by 32-channel Time Domain Functional Near Infrared Spectroscopy -- NIRS-based Neurofeedback Learning Systems for Controlling Activity of the Prefrontal Cortex -- Cortical Mapping of 3D Optical Topography in Infants -- Monitoring of Hemodynamic Change in Patients with Carotid Artery Stenosis during the Tilt Test using Wearable Near-infrared Spectroscopy -- Index.

Additional Edition: ISBN 9781461472568

Additional Edition: Print version Oxygen Transport to Tissue XXXV

Language: English

Subjects: Biology

DOI: 10.1007/978-1-4614-7411-1

URL: Volltext  (lizenzpflichtig)

UID:

Format: Online-Ressource (XXX, 372 p.) , Ill.

Edition: Online-Ausg. Springer eBook Collection. Biomedical and Life Sciences

ISBN: 9781493906208

Series Statement: Advances in Experimental Medicine and Biology 812

Content: This book contains the refereed contributions from the 41st annual meeting of ISOTT. The annual meetings of ISOTT bring together scientists from various fields (medicine, physiology, mathematics, biology, chemistry, physics, engineering, etc.) in a unique international forum. Traditionally, ISOTT conferences are a place, where an atmosphere of interaction is created, where many questions are asked after each presentation and lively discussions occur at a high scientific level. This vivid interaction is the main motivation for members to participate and gain new ideas and knowledge in the broad field of oxygen transport to tissue. The papers in this volume summarize some of the outstanding contributions from the 41st annual meeting. Special features in this volume include invited presentations from senior members of ISOTT for the theme “the wisdom of ISOTT” in which founders, past presidents and prize winners from previous meetings provided both cutting edge new knowledge and integrated overviews of critical aspects of the field. The presentations and manuscripts also include those provided by the special opportunity provided by having part of the ISOTT meeting overlap with the EPR-2013 meeting where both focused on preclinical and clinical measurements of oxygen, with a particular emphasis on cancer

Note: Description based upon print version of record , Dedication; Preface; Acknowledgements; Panel of Reviewers; Local Organizing Committee: The Geisel School of Medicine at Dartmouth; Scientific Advisory Committee; ISOTT Officers and Executive Committee; ISOTT Award Winners; The Melvin H. Knisely Award; Melvin H. Knisely Award Recipients; The Dietrich W. Lübbers Award; Dietrich W. Lübbers Award Recipients; The Britton Chance Award; Britton Chance Award Recipients; The Duane F. Bruley Travel Awards; Duane F. Bruley Award Recipients; Kovach Lecture; Kovach Lecture Recipients; Contents , Chapter 1: Mitochondrial Genetic Abnormalities After Radiation Exposure1 Introduction; 2 Methods; 3 Results; 4 Discussion; 5 Conclusion; References; Chapter 2: Crediting Six Discoverers of Oxygen; Chapter 3: Hypoxia in Tumors: Pathogenesis-Related Classification, Characterization of Hypoxia Subtypes, and Associated Biological and Clinical Implications; 1 Introduction; 2 Chronic Hypoxia; 3 Acute Hypoxia; 4 Hypoxia-Associated Biological and Clinical Implications; 5 Conclusions; References , Chapter 4: Heterogeneity in Tissue Oxygenation: From Physiological Variability in Normal Tissues to Pathophysiological Chaos in Malignant Tumours1 Heterogeneity of Blood Flow; 2 Heterogeneity of Oxygen Supply: The Tissue pO 2 Histogram; 3 Physiological Response of Tissue O 2 Supply; 4 Pathological Responses of Tissue O 2 Supply in Normal Microvasculature and in Malignant Tumours; 5 Conclusions; References; Chapter 5: Oxygen Diffusion: An Enzyme-Controlled Variable Parameter; 1 Introduction; 2 Methods; 3 Results; 4 Discussion; 5 Conclusion; References , Chapter 6: Role of Microvascular Shunts in the Loss of Cerebral Blood Flow Autoregulation1 Introduction; 2 Methods; 2.1 Two Photon Laser Scanning Microscopy Studies; 2.1.1 Microvascular Shunting by Increasing Intracranial Pressure; 2.1.2 Increasing CPP Attenuates the Transition from Capillary Flow to Microvascular Shunts with Increasing ICP; 2.2 Multimodal Monitoring System in Patients; 3 Results; 4 Discussion; 5 Conclusions; References; Chapter 7: Impact of Hypoxia-Related Tumor Acidosis on Cytotoxicity of Different Chemotherapeutic Drugs In Vitro and In Vivo; 1 Introduction , 2 Material and Methods2.1 Cell Lines; 2.2 Chemotherapy; 2.3 Forcing Glycolytic Metabolism; 2.4 Measurement of Apoptosis Induction and Cell Survival; 3 Results; 4 Discussion; References; Chapter 8: The Founding of ISOTT: The Shamattawa of Engineering Science and Medical Science; 1 The Merging of Engineering and Medical Sciences; References; Chapter 9: A Tale of Two Methods: Combining Near-­Infrared Spectroscopy with MRI for Studies of Brain Oxygenation and Metabolism; 1 Introduction; 2 Fiber Optics and MRI, the Issues and Solutions to Multimodality Imaging , 3 Advantages of Combining NIRS and MRI , Mitochondrial Genetic Abnormalities after Radiation ExposureCrediting Six Discoverers of Oxygen -- Hypoxia in Tumors: Pathogenesis-related Classification, Characterization of Hypoxia subtypes, and Associated Biological and Clinical Implications -- Heterogeneity in Tissue Oxygenation: From Physiological Variability in Normal Tissues to Pathophysiological Chaos in Malignant Tumours -- Oxygen Diffusion: An Enzyme-controlled Variable Parameter -- Role of Microvascular Shunts in the Loss of Cerebral Blood Flow Autoregulation -- Impact of Hypoxia-related Tumor Acidosis on Cytotoxicity of Different Chemotherapeutic Drugs in vitro and in vivo -- The Founding of ISOTT: The Shamattawa of Engineering Science and Medical Science -- A Tale of Two Methods: Combining Near-Infrared Spectroscopy with MRI for Studies of Brain Oxygenation and Metabolism -- Advances in Probes and Methods for Clinical EPR Oximetry -- Real-Time, In Vivo Determination of Dynamic Changes in Lung and Heart Tissue Oxygenation using EPR Oximetry -- Modulation of Hypoxia by Magnetic Nanoparticle Hyperthermia to Augment Therapeutic Index -- Skeletal Muscle and Glioma Oxygenation by Carbogen Inhalation in Rats: A Longitudinal Study by EPR Oximetry using Single-Probe Implantable Oxygen Sensors -- Recurrent Low-dose Chemotherapy to Inhibit and Oxygenate Head and Neck Tumors -- How in vivo EPR Measures and Images Oxygen -- What We Learn From In Vivo EPR Oxygen Images -- EPR Image Based Oxygen Movies for Transient Hypoxia -- Repetitive Measurements of Intrarenal Oxygenation in vivo using L band Electron Paramagnetic Resonance -- Quantitative Hypoxia Imaging for Treatment Planning of Radiotherapy -- A New Flavonoid Regulates Angiogenesis and Reactive Oxygen Species Production -- Angiotensin II Reduces Transport-Dependent Oxygen Consumption but Increases Transport-Independent Oxygen Consumption in Immortalized Mouse Proximal Tubular Cells -- Investigation of Cerebral Autoregulation in the Newborn Piglet during Anaesthesia and Surgery -- Influence of the Maternal use of Labetalol on the Neurogenic Mechanism for Cerebral Autoregulation Assessed by Means of NIRS -- Development of a Near Infrared Multi-Wavelength, Multi-channel, Time-Resolved Spectrometer for Measuring Brain Tissue Haemodynamics and Metabolism -- Simulating NIRS and MRS measurements during cerebral hypoxia-ischaemia in piglets using a computational model -- Analysis of Slow Wave Oscillations in Cerebral Haemodynamics and Metabolism Following Subarachnoid Haemorrhage -- Effects of Enriched Environment on Hippocampal Neuronal Cell Death and Neurogenesis in Rat Global Ischemia -- Automated Image Analysis for Diameters and Branching Points of Cerebral Penetrating Arteries and Veins Captured with Two-Photon Microscopy -- Cerebral Hemodynamic Changes and Metabolic Alteration in Severe Hemorrhagic Shock -- Physiological Mechanism of Increase in Deoxy-hemoglobin Concentration during Neuronal Activation in Patients with Cerebral Ischemia: A Simulation Study with the Balloon Model -- Effect of Blood in the Cerebrospinal Fluid on the Accuracy of Cerebral Oxygenation Measured by Near Infrared Spectroscopy -- Vessel Specific Imaging of Glucose Transfer with Fluorescent Glucose Analogue in Anesthetized Mouse Cortex -- Ischemic Pretreatment Delays Ischemic Brain Vasospasm Injury in Gerbils -- Changes in Cerebral Blood Oxygenation Induced by Active Standing Test in Children with POTS and NMS -- Optical Imaging of Brain Activation in Gambian Infants -- Asymmetrical Changes in Cerebral Blood Oxygenation Induced by an Active Standing Test in Children with Postural Tachycardia Syndrome -- Changes of Cerebral Tissue Oxygen Saturation at Sleep Transitions in Adolescents -- Influence of Subjective Happiness on the Prefrontal Brain Activity: An fNIRS Study -- Ginkobiloba Extract Improves Working Memory Performance in Middle-aged women; Role of Asymmetry of Prefrontal Cortex Activity during a Working Memory Task -- Bayesian Prediction of Anxiety Level in Aged People at Rest using 2-Channel NIRS Data from Prefrontal Cortex -- Short-term Hypoxic Preconditioning Improved Survival following Cardiac Arrest and Resuscitation in rats -- Venular Valves and Retrograde Perfusion -- Monitoring of Filter Patency during Carotid Artery Stenting using Near-Infrared Spectroscopy with High Time-Resolution -- Use of NIRS to Assess Effect of Training on Peripheral Muscle Oxygenation Changes in Elite Rugby Players Performing Repeated Supramaximal Cycling Tests -- Skeletal Muscle Deoxygenation Responses during Treadmill Exercise in Children -- Development of a Hybrid Microwave-Optical Thermoregulation Monitor for the Muscle -- Evaluation of a Textile-Based Near Infrared Spectroscopy System in Calf Muscle Oxygenation Measurements -- Skin Temperature in Lower Hind Limb Subjected to Distal Vein Arterialization in Rats -- Index.

Additional Edition: ISBN 9781493905836

Additional Edition: Print version Oxygen Transport to Tissue XXXVI

Language: English

Subjects: Biology

Keywords: Sauerstoffversorgung

DOI: 10.1007/978-1-4939-0620-8

URL: Volltext  (lizenzpflichtig)

URL: Volltext

UID:

Format: Online-Ressource (digital)

ISBN: 9780387749112

Series Statement: Advances In Experimental Medicine And Biology 614

Additional Edition: ISBN 9780387749105

Additional Edition: Buchausg. u.d.T. Oxygen transport to tissue XXIX New York, NY : Springer, 2008 ISBN 9780387749105

Additional Edition: ISBN 0387749101

Language: English

Subjects: Biology

Keywords: Sauerstoffstoffwechsel ; Sauerstofftransport

DOI: 10.1007/978-0-387-74911-2

URL: Volltext  (lizenzpflichtig)

URL: Cover

URL: Inhaltsverzeichnis

URL: Kapitel 2

UID:

Format: Online-Ressource (digital)

ISBN: 9780387859989

Series Statement: Advances in Experimental Medicine and Biology 645

Content: This book covers all aspects of oxygen delivery to tissue, including blood flow and its regulation as well as oxygen metabolism. Special attention will be paid to methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. This book is multidisciplinary and designed to bring together experts and students from a range of research fields including biochemical engineering, physiology, microcirculation, and hematology.

Content: Covers various aspects of oxygen delivery to tissue, including blood flow and its regulation as well as oxygen metabolism. This book pays attention to methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation

Note: Includes bibliographical references and index , Selected conference papers , CONTENTS; AIR AND FIRE - Carl Wilhelm Scheele, Torbern Bergman, The Royal Society of Sciences and the discovery of oxygen in Uppsala in 1772; MATHEMATICAL MODELING OF THE INTERACTION BETWEEN OXYGEN, NITRIC OXIDE AND SUPEROXIDE; HAEMOGLOBIN SATURATION CONTROLS THE RED BLOOD CELL MEDIATED HYPOXIC VASORELAXATION; BLOOD VESSEL SPECIFIC VASO-ACTIVITY TO NITRITE UNDER NORMOXIC AND HYPOXIC CONDITIONS; NITRITE-INDUCED IMPROVED BLOOD CIRCULATION ASSOCIATED WITH AN INCREASE IN A POOL OF RBC-NO WITH NO BIOACTIVITY; THE CONTROL OF OXIDATIVE PHOSPHORYLATION IN THE ADRENAL GLAND (Y1) CELL LINE , REPLICATION OF MURINE MITOCHONDRIAL DNA FOLLOWING IRRADIATIONEFFECTS OF ANESTHESIA ON BRAIN MITOCHONDRIAL FUNCTION, BLOOD FLOW, IONIC AND ELECTRICAL ACTIVITY MONITORED IN VIVO; THE INFLUENCE OF FLOW REDISTRIBUTION ON WORKING RAT MUSCLE OXYGENATION; HETEROGENEITY OF CAPILLARY SPACING IN THE HYPERTROPHIED PLANTARIS MUSCLE FROM YOUNG-ADULT AND OLD RATS; MICROVASCULARITY OF THE LUMBAR ERECTOR SPINAE MUSCLE DURING SUSTAINED PRONE TRUNK EXTENSION TEST; FIBER CAPILLARY SUPPLY RELATED TO FIBER SIZE ANDOXIDATIVE CAPACITY IN HUMAN AND RAT SKELETAL MUSCLE , NOVEL THERAPEUTIC APPROACH TARGETING THE HIF-HRE SYSTEM IN THE KIDNEYCAROTID BODY SENSORY DISCHARGE AND GLOMUS CELL HIF-1a ARE REGULATED BY A COMMON OXYGEN SENSOR; IMPACT OF REACTIVE OXYGEN SPECIES ON THE EXPRESSION OF ADHESION MOLECULES IN VIVO; MINI SENSING CHIP FOR POINT-OF-CARE ACUTE MYOCARDIAL INFARCTION DIAGNOSIS UTILIZING MICRO-ELECTRO-MECHANICAL SYSTEM AND NANO-TECHNOLOGY; A CHEMICAL BIOSYNTHESIS DESIGN FOR AN ANTIATHEROSCLEROSIS DRUG BY ACYCLIC TOCOPHEROL INTERMEDIATE ANALOGUE BASED ON "ISOPRENOMICS"; ZYMOGEN PROTEIN C CONCENTRATE FOR SAFER HETEROZYGOTE SURGERY, "I AM A GUINEA PIG!" , STEADY STATE REDOX LEVELS IN CYTOCHROME OXIDASE: RELEVANCE FOR IN VIVO NEAR INFRARED SPECTROSCOPY (NIRS)BICUCULLINE-INDUCED SEIZURES: A CHALLENGE FOR OPTICAL AND BIOCHEMICAL MODELING OF THE CYTOCHROME OXIDASE CU A NIRS SIGNAL; A METHOD TO CALCULATE ARTERIAL AND VENOUS SATURATION FROM NEAR INFRARED SPECTROSCOPY (NIRS); DEVELOPMENT OF A DYNAMIC TEST PHANTOM FOR OPTICAL TOPOGRAPHY; NUMERICAL SIMULATION OF OXYGEN TRANSPORT IN CEREBRAL TISSUE; NON-INVASIVE ESTIMATION OF METABOLIC FLUX AND BLOOD FLOW IN WORKING MUSCLE: EFFECT OF BLOOD-TISSUE DISTRIBUTION , OXYGEN EXTRACTION INDEX MEASURED BY NEAR INFRAREDSPECTROSCOPY - A PARAMETER FOR MONITORING TISSUEOXYGENATION?NON-INVASIVE MEASUREMENT OF THE SUPERFICIAL CORTICAL OXYGEN PARTIAL PRESSURE; ONE SENSOR FITS ALL - A NEW APPROACH IN MONITORING BRAIN PHYSIOLOGY; EVALUATION OF NIRS DATA BASED ON THEORETICAL ANALYSIS OF OXYGEN TRANSPORT TO CEREBRAL TISSUE; MYOCARDIAL CAPILLARY NET AND BLOOD CONSTITUENTS IN STREPTOZOTOCIN (STZ)- INDUCED DIABETIC RATS; EFFECTS OF PROINSULIN C-PEPTIDE ON OXYGEN TRANSPORT, UPTAKE AND UTILIZATION IN INSULINOPENIC DIABETIC SUBJECTS - A REVIEW , REDUCED OXYGENATION IN DIABETIC RAT KIDNEYS MEASURED BY T2* WEIGHTED MAGNETIC RESONANCE MICRO-IMAGING , Air and fire : Carl Wilhelm Scheele, Torbern Bergman, the Royal Society of Sciences and the discovery of oxygen in Uppsala in 1772 , Haemoglobin saturation controls the red blood cell mediated hypoxic vasorelaxation , Blood vessel specific vaso-activity to nitrite under normoxic and hypoxic conditions , Nitrite-induced improved blood circulation associated with an increase in a pool of RBN-NO with NO bioactivity , The control of oxidative phosphorylation in the adrenal gland (Y1) cell line , Replication of murine mitochondrial DNA following irradiation , Effects of anesthesia on brain mitochondrial function, blood flow, ionic and electrical activity monitored in vivo , The influence of flow redistribution on working rat muscle oxygenation , Heterogeneity of capillary spacing in the hypertrophied plantaris muscle from young-adult and old rats , Microvascularity of the lumbar erector spinae muscle during sustained prone trunk extension test , Fiber capillary supply related to fiber size and oxidative capacity in human and rat skeletal muscle , Novel therapeutic approach targeting the HIF-HRE system in the kidney , Carotid body sensory discharge and glomus cell HIF-1[alpha] are regulated by a common oxygen sensor , Impact of reactive oxygen species on the expression of adhesion molecules in vivo , Mini sensing chip for point-of-care acute myocardial infarction diagnosis utilizing micro-electro-mechanical system and nano-technology , A chemical biosynthesis design for an antiatherosclerosis drug by acyclic tocopherol intermediate analogue based on "isoprenomics" , Zymogen protein C concentrate for safer heterozygote surgery, "I am a guinea pig!" , Steady state redox levels in cytochrome oxidase : relevance for in vivo near infrared spectroscopy (NIRS) , Bicuculline-induced seizures : a challenge for optical and biochemical modeling of the cytochrome oxidase CUa NIRS signal , A method to calculate arterial and venous saturation from near infrared spectroscopy (NIRS) , Development of a dynamic test phantom for optical topography , Numerical simulation of oxygen transport in cerebral tissue , Non-invasive estimation of metabolic flux and blood flow in working muscle : effect of blood-tissue distribution , Oxygen extraction index measured by near infrared spectroscopy : a parameter for monitoring tissue oxygenation? , Non-invasive measurement of the superficial cortical oxygen partial pressure , One sensor fits all : a new approach in monitoring brain physiology , Evaluation of NIRS data based on theoretical analysis of oxygen transport to cerebral tissue , Myocardial capillary net and blood constituents in streptozotocin (STZ- )-induced diabetic rats , Effects of proinsulin C-peptide on oxygen transport uptake and utilization in insulinopenic diabetic subjects : a review , Reduced oxygenation in diabetic rat kidneys measured by T2* weighted magnetic resonance micro-imaging , Identification and distribution of uncoupling protein isoforms in the normal and diabetic rat kidney , Iodinated contrast media decrease renomedullary blood flow : a possible cause of contrast media-induced nephropathy , C-peptide normalizes glomerular filtration rate in hyperfiltrating conscious diabetic rats , Lipoprotein nanoplatform for targeted delivery of diagnostic and therapeutic agents , Prognostic potential of the pre-therapeutic tumor oxygenation status , Histological basis of MR/optical imaging of human melanoma mouse xenografts spanning a range of metastatic potentials , The relationship between vascular oxygen distribution and tissue oxygenation , Intraoperative measurement of colonic oxygenation during bowel resection , Quantifying tumour hypoxia by PET imaging : a theoretical analysis , New measurements for assessment of impaired cerebral autoregulation using near-infrared spectroscopy , Single shot T₁p magnetic resonance imaging of metabolically generated water in vivo , Brain tissue oxygen consumption and supply induced by neural activation : determined under suppressed hemodynamic response conditions in the anesthetized rat cerebral cortex , Brain oxygen balance under various experimental pathophysiological conditions , Ketones suppress brain glucose consumption , False positives in functional near-infrared topography , Relationship between brain tissue haemodynamics, oxygenation, and metabolism in the healthy human adult brain during hyperoxia and hypercapnea , Use of a Codman microsensor intracranial pressure probe : effects on near infrared spectroscopy measurements and cerebral hemodynamics in rats , Effect of severe hypoxia on prefrontal cortex and muscle oxygenation responses at rest and during exhaustive exercise

Additional Edition: ISBN 9780387859972

Additional Edition: Buchausg. u.d.T. Oxygen transport to tissue ; 30 New York, NY : Springer, 2009 ISBN 9780387859972

Language: English

Subjects: Biology

Keywords: Sauerstofftransport ; Gewebestoffwechsel ; Sauerstofftransport ; Gewebestoffwechsel ; Konferenzschrift

DOI: 10.1007/978-0-387-85998-9

URL: Volltext

URL: Volltext  (lizenzpflichtig)

URL: Cover

UID:

Format: Online-Ressource (digital)

ISBN: 9780387717647

Series Statement: Advances in Experimental Medicine and Biology 599

Note: "Proceedings from the 33rd Annual Meeting of the International Society on Oxygen Transport to Tissue (ISOTT) held in Brisbane, Australia, August 28-September 2, 2005"--T.p. verso , Includes bibliographical references and indexes

Additional Edition: ISBN 9780387717630

Additional Edition: Buchausg. u.d.T. ISBN 978-0-387-71763-0

Language: English

Subjects: Biology

Keywords: Sauerstoffstoffwechsel ; Sauerstofftransport

DOI: 10.1007/978-0-387-71764-7

URL: Volltext

URL: Volltext  (lizenzpflichtig)

URL: Cover