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  • 1
    In: Urologia Internationalis, S. Karger AG, Vol. 101, No. 1 ( 2018), p. 16-24
    Kurzfassung: 〈 b 〉 〈 i 〉 Background/Aims/Objectives: 〈 /i 〉 〈 /b 〉 To evaluate the influence of body mass index (BMI) on complications and oncological outcomes in patients undergoing radical cystectomy (RC). 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 Clinical and histopathological parameters of patients have been prospectively collected within the “PROspective MulticEnTer RadIcal Cystectomy Series 2011”. BMI was categorized as normal weight ( & #x3c;25 kg/m 〈 sup 〉 2 〈 /sup 〉 ), overweight (≥25–29.9 kg/m 〈 sup 〉 2 〈 /sup 〉 ) and obesity (≥30 kg/m 〈 sup 〉 2 〈 /sup 〉 ). The association between BMI and clinical and histopathological endpoints was examined. Ordinal logistic regression models were applied to assess the influence of BMI on complication rate and survival. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Data of 671 patients were eligible for final analysis. Of these patients, 26% ( 〈 i 〉 n 〈 /i 〉 = 175) showed obesity. No significant association of obesity on tumour stage, grade, lymph node metastasis, blood loss, type of urinary diversion and 90-day mortality rate was found. According to the ­American Society of Anesthesiologists score, local lymph node (NT) stage and operative case load patients with higher BMI had significantly higher probabilities of severe complications 30 days after RC ( 〈 i 〉 p 〈 /i 〉 = 0.037). The overall survival rate of obese patients was superior to normal weight patients ( 〈 i 〉 p 〈 /i 〉 = 0.019). 〈 b 〉 〈 i 〉 Conclusions: 〈 /i 〉 〈 /b 〉 There is no evidence of correlation between obesity and worse oncological outcomes after RC. While obesity should not be a parameter to exclude patients from cystectomy, surgical settings need to be aware of higher short-term complication risks and obese patients should be counselled ­accordingly.
    Materialart: Online-Ressource
    ISSN: 0042-1138 , 1423-0399
    RVK:
    Sprache: Englisch
    Verlag: S. Karger AG
    Publikationsdatum: 2018
    ZDB Id: 1464417-4
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Online-Ressource
    Online-Ressource
    S. Karger AG ; 2020
    In:  Oncology Research and Treatment Vol. 43, No. 5 ( 2020), p. 228-236
    In: Oncology Research and Treatment, S. Karger AG, Vol. 43, No. 5 ( 2020), p. 228-236
    Kurzfassung: 〈 b 〉 〈 i 〉 Aims: 〈 /i 〉 〈 /b 〉 The study aimed to evaluate the prevalence of mental distress in patients with newly diagnosed bladder cancer, the cancer-information search behavior, and the influence of information seeking on distress. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 One hundred and one bladder cancer patients answered 2 established questionnaires (“Hospital Anxiety and Depression Scale” [HADS] and the “Fragebogen zur Belastung von Krebskranken” [FBK-R23] ) for evaluation of mental distress and a self-developed questionnaire with questions concerning information seeking and socioeconomic facts. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Regarding risk group stratification, 57.4% were classified as high-risk and 42.6% as low-risk tumor-bearing patients. Analysis of mental distress showed that 23.2% had a score above the HADS-A cutoff, 25.3% above the HADS-D cutoff, and 21.4% showed a pathologic FBK-R23 score. Overall, 75% felt well informed about their illness. Risk group stratification did not correlate with HADS-A, HADS-D, or FBK-R23 score. Furthermore, active search for information or the use of the Internet did not correlate with the HADS-A, HADS-D, or FBK-R23 score. However, the quality of the urologist’s information and the feeling of being informed correlated with the grade of mental distress. 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 Besides the treatment of bladder cancer, informing the patient about the disease in a psychologically wholesome manner and working together with psycho-oncologically trained psychologists are essential tasks for the treating urologist.
    Materialart: Online-Ressource
    ISSN: 2296-5270 , 2296-5262
    Sprache: Englisch
    Verlag: S. Karger AG
    Publikationsdatum: 2020
    ZDB Id: 2749752-5
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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