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  • 1
    In: Global Spine Journal, SAGE Publications
    Abstract: Systematic review of the literature and subsequent meta-analysis for the development of a new guideline. Objectives This manuscript summarizes the recommendations from a new clinical guideline published by the German Spine Society. It covers the current evidence on recommendations regarding the indication, test blocks and use of radiofrequency denervation. The guidelines aim is to improve patient care and efficiency of the procedure. Methods A multidisciplinary working group formulated recommendations based on the Grades of Recommendations, Assessment, Development, and Evaluation (GRADE) approach and the Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument. Results 20 clinical questions were defined for guideline development, with 87.5% consensus achieved by committee members for one recommendation and 100% consensus for all other topics. Specific questions that were addressed included clinical history, examination and imaging, conservative treatment before injections, diagnostic blocks, the injected medications, the cut-off value in pain-reduction for a diagnostic block as well as the number of blocks, image guidance, the cannula trajectories, the lesion size, stimulation, repeat radiofrequency denervation, sedation, cessation or continuation of anticoagulants, the influence of metal hardware, and ways to mitigate complications. Conclusion Radiofrequency (RF) denervation of the spine and the SI joint may provide benefit to well-selected individuals. The recommendations of this guideline are based on very low to moderate quality of evidence as well as professional consensus. The guideline working groups recommend that research efforts in relation to all aspects of management of facet joint pain and SI joint pain should be intensified.
    Type of Medium: Online Resource
    ISSN: 2192-5682 , 2192-5690
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2024
    detail.hit.zdb_id: 2648287-3
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  • 2
    Online Resource
    Online Resource
    SAGE Publications ; 2020
    In:  Human Factors: The Journal of the Human Factors and Ergonomics Society Vol. 62, No. 5 ( 2020-08), p. 718-736
    In: Human Factors: The Journal of the Human Factors and Ergonomics Society, SAGE Publications, Vol. 62, No. 5 ( 2020-08), p. 718-736
    Abstract: This paper presents a theoretical model and two simulator studies on the psychological processes during early trust calibration in automated vehicles. Background The positive outcomes of automation can only reach their full potential if a calibrated level of trust is achieved. In this process, information on system capabilities and limitations plays a crucial role. Method In two simulator experiments, trust was repeatedly measured during an automated drive. In Study 1, all participants in a two-group experiment experienced a system-initiated take-over, and the occurrence of a system malfunction was manipulated. In Study 2 in a 2 × 2 between-subject design, system transparency was manipulated as an additional factor. Results Trust was found to increase during the first interactions progressively. In Study 1, take-overs led to a temporary decrease in trust, as did malfunctions in both studies. Interestingly, trust was reestablished in the course of interaction for take-overs and malfunctions. In Study 2, the high transparency condition did not show a temporary decline in trust after a malfunction. Conclusion Trust is calibrated along provided information prior to and during the initial drive with an automated vehicle. The experience of take-overs and malfunctions leads to a temporary decline in trust that was recovered in the course of error-free interaction. The temporary decrease can be prevented by providing transparent information prior to system interaction. Application Transparency, also about potential limitations of the system, plays an important role in this process and should be considered in the design of tutorials and human-machine interaction (HMI) concepts of automated vehicles.
    Type of Medium: Online Resource
    ISSN: 0018-7208 , 1547-8181
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2066426-6
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  • 3
    In: Acta Radiologica, SAGE Publications, Vol. 54, No. 2 ( 2013-03), p. 137-143
    Abstract: Breast cancer screening programs have been established worldwide and early detection of breast cancer has increased steadily. The most common way to confirm dignity of non-palpable and sonographically-occult suspicious findings on mammography is the stereotactically-guided vacuum-assisted breast biopsy Purpose To compare two stereotactically guided vacuum-assisted breast biopsy systems measuring time effectiveness and quality of harvested material in clinical practice. Material and Methods One hundred and forty-six patients presenting with suspicious microcalcifications on mammography were included in the study. Biopsies were carried out with either the Mammotome ® system (11-gauge and 8-gauge) or the ATEC ® system (12-gauge and 9-gauge). Lesions with a diameter 〈 15 mm on mammography were biopsied with 11-gauge or 12-gauge devices whereas lesions 〉 15 mm were targeted with 8-gauge and 9-gauge. Mammotome ® system 8-gauge device was used in 34 patients, the 11-gauge system in 37 patients. The ATEC ® system 9-gauge system was used in 37 patients and 12-gauge in 38 patients. Time was taken, focusing on preparing the system, time of collecting the samples, preparing the samples, and cleaning the site. During the biopsies 24 samples were taken. The histologic quality of the tissue samples was judged by a pathologist in a blinded fashion according to a specimen grading classification concerning tissue fragmentation, artefacts, and the adequacy of the tissue for diagnosis. Results The median overall time for the Mammotome ® system was 879 s (11-gauge) and 934 s (8-gauge) and for the ATEC ® system 671 s (12-gauge) and 673 s (9-gauge). The ATEC ® system displays a significantly shorter overall time for small and large biopsy devices (U-test, P 〈 0.001). Concerning the mean time difference of the overall time comparing small and large systems the ATEC ® system was 267.6 s faster using the small and 244.8 s faster using the large system. Comparing the histologic quality of tissue samples the Mammotome ® system shows significantly higher values for the large and the small system (Chi-square test, P 〈 0.001). Conclusion Both biopsy systems meet all requirements for daily practice and confirm the diagnosis of suspicious microcalcifications. The ATEC ® system was observed to be faster but this difference of about 250 s might not be relevant in daily practice. The Mammotome ® system provides a better histologic quality of tissue samples.
    Type of Medium: Online Resource
    ISSN: 0284-1851 , 1600-0455
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 2024579-8
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  • 4
    In: European Stroke Journal, SAGE Publications
    Abstract: Cerebral venous sinus thrombosis associated with vaccine-induced immune thrombotic thrombocytopenia (CVST-VITT) is a severe disease with high mortality. There are few data on sex differences in CVST-VITT. The aim of our study was to investigate the differences in presentation, treatment, clinical course, complications, and outcome of CVST-VITT between women and men. Patients and methods: We used data from an ongoing international registry on CVST-VITT. VITT was diagnosed according to the Pavord criteria. We compared the characteristics of CVST-VITT in women and men. Results: Of 133 patients with possible, probable, or definite CVST-VITT, 102 (77%) were women. Women were slightly younger [median age 42 (IQR 28–54) vs 45 (28–56)], presented more often with coma (26% vs 10%) and had a lower platelet count at presentation [median (IQR) 50x10 9 /L (28–79) vs 68 (30–125)] than men. The nadir platelet count was lower in women [median (IQR) 34 (19–62) vs 53 (20–92)] . More women received endovascular treatment than men (15% vs 6%). Rates of treatment with intravenous immunoglobulins were similar (63% vs 66%), as were new venous thromboembolic events (14% vs 14%) and major bleeding complications (30% vs 20%). Rates of good functional outcome (modified Rankin Scale 0-2, 42% vs 45%) and in-hospital death (39% vs 41%) did not differ. Discussion and conclusions: Three quarters of CVST-VITT patients in this study were women. Women were more severely affected at presentation, but clinical course and outcome did not differ between women and men. VITT-specific treatments were overall similar, but more women received endovascular treatment.
    Type of Medium: Online Resource
    ISSN: 2396-9873 , 2396-9881
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2851287-X
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  • 5
    Online Resource
    Online Resource
    SAGE Publications ; 2021
    In:  Human Factors: The Journal of the Human Factors and Ergonomics Society Vol. 63, No. 6 ( 2021-09), p. 1076-1105
    In: Human Factors: The Journal of the Human Factors and Ergonomics Society, SAGE Publications, Vol. 63, No. 6 ( 2021-09), p. 1076-1105
    Abstract: This paper presents a comprehensive investigation of personality traits related to trust in automated vehicles. A hierarchical personality model based on Mowen’s (2000) 3M model is explored in a first and replicated in a second study. Background Trust in automation is established in a complex psychological process involving user-, system- and situation-related variables. In this process, personality traits have been viewed as an important source of variance. Method Dispositional variables on three levels were included in an exploratory, hierarchical personality model (full model) of dynamic learned trust in automation, which was refined on the basis of structural equation modeling carried out in Study 1 (final model). Study 2 replicated the final model in an independent sample. Results In both studies, the personality model showed a good fit and explained a large proportion of variance in trust in automation. The combined evidence supports the role of extraversion, neuroticism, and self-esteem at the elemental level; affinity for technology and dispositional interpersonal trust at the situational level; and propensity to trust in automation and a priori acceptability of automated driving at the surface level in the prediction of trust in automation. Conclusion Findings confirm that personality plays a substantial role in trust formation and provide evidence of the involvement of user dispositions not previously investigated in relation to trust in automation: self-esteem, dispositional interpersonal trust, and affinity for technology. Application Implications for personalization of information campaigns, driver training, and user interfaces for trust calibration in automated driving are discussed.
    Type of Medium: Online Resource
    ISSN: 0018-7208 , 1547-8181
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2066426-6
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  • 6
    Online Resource
    Online Resource
    SAGE Publications ; 2010
    In:  Journal of Marketing Research Vol. 47, No. 4 ( 2010-08), p. 685-698
    In: Journal of Marketing Research, SAGE Publications, Vol. 47, No. 4 ( 2010-08), p. 685-698
    Abstract: Conjoint analysis has become a widely accepted tool for preference measurement in marketing research, though its applicability and performance strongly depend on the complexity of the product or service. Therefore, self-explicated approaches are still frequently used because of their simple design, which facilitates preference elicitation when large numbers of attributes need to be considered. However, the direct measurement of preferences, or rather utilities, has been criticized as being imprecise in many cases. Against this background, the authors present a compositional consumer preference measurement approach based on paired comparisons, otherwise known as PCPM. The trade-off character of paired comparisons ensures that the stated judgments are more intuitive than traditional self-explicated preference statements. In contrast to the latter, PCPM accounts for response errors and thus allows for the elicitation of more precise preferences. The authors benchmark PCPM against adaptive conjoint analysis and computer-assisted self-explication of multiattributed preferences to demonstrate its relative validity and predictive accuracy in two empirical studies using complex, high-involvement products. They find that PCPM yields better results than the benchmark approaches with respect to interview length, individual hit rates, and aggregate choice share predictions.
    Type of Medium: Online Resource
    ISSN: 0022-2437 , 1547-7193
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2010
    detail.hit.zdb_id: 2066604-4
    detail.hit.zdb_id: 218319-5
    SSG: 3,2
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  • 7
    Online Resource
    Online Resource
    SAGE Publications ; 2005
    In:  Simulation & Gaming Vol. 36, No. 3 ( 2005-09), p. 364-382
    In: Simulation & Gaming, SAGE Publications, Vol. 36, No. 3 ( 2005-09), p. 364-382
    Abstract: The authors developed SIMULME, an Internet-based simulation game of the environmental and economic consequences of food consumption, to improve environmental knowledge, attitudes, and behaviors of individuals. The game was first applied with 215 pupils divided into 12 classes. Six classes were taught the consequences of food consumption using the learning game (experimental condition) and 6 using a standard lecture (control condition). Positive changes in environmental attitudes concerning nutrition behavior were more marked in the experimental than in the control condition. An additional experiment tested the game’s effects on subsequent buying behavior. After playing the game (experimental) or not (control), participants entered the nutrition section of the online shop of the Swiss retailer Coop with the possibility of winning a purchase worth CHF 40. The consumption pattern of those who played SIMULME was ecologically more positive than that of the control participants. Aspects of game validity and game design are discussed with respect to the effectiveness of games for environmental education.
    Type of Medium: Online Resource
    ISSN: 1046-8781 , 1552-826X
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2005
    detail.hit.zdb_id: 83146-3
    detail.hit.zdb_id: 2030794-9
    detail.hit.zdb_id: 1051755-8
    SSG: 3,2
    SSG: 17,1
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