In:
PLOS ONE, Public Library of Science (PLoS), Vol. 17, No. 8 ( 2022-8-11), p. e0267705-
Abstract:
Genomic research and neurobiobanking are expanding globally. Empirical evidence on the level of awareness and willingness to donate/share biological samples towards the expansion of neurobiobanking in sub-Saharan Africa is lacking. Aims To ascertain the awareness, perspectives and predictors regarding biological sample donation, sharing and informed consent preferences among community members in Ghana and Nigeria. Methods A questionnaire cross-sectional survey was conducted among randomly selected community members from seven communities in Ghana and Nigeria. Results Of the 1015 respondents with mean age 39.3 years (SD 19.5), about a third had heard of blood donation (37.2%, M: 42.4%, F: 32.0%, p = 0.001) and a quarter were aware of blood sample storage for research (24.5%; M: 29.7%, F: 19.4%, p = 0.151). Two out of ten were willing to donate brain after death (18.8%, M: 22.6%, F: 15.0%, p 〈 0.001). Main reasons for unwillingness to donate brain were; to go back to God complete (46.6%) and lack of knowledge related to brain donation (32.7%). Only a third of the participants were aware of informed consent (31.7%; M: 35.9%, F: 27.5%, p 〈 0.001). Predictors of positive attitude towards biobanking and informed consent were being married, tertiary level education, student status, and belonging to select ethnic groups. Conclusion There is a greater need for research attention in the area of brain banking and informed consent. Improved context-sensitive public education on neurobiobanking and informed consent, in line with the sociocultural diversities, is recommended within the African sub region.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0267705
DOI:
10.1371/journal.pone.0267705.t001
DOI:
10.1371/journal.pone.0267705.t002
DOI:
10.1371/journal.pone.0267705.t003
DOI:
10.1371/journal.pone.0267705.t004
DOI:
10.1371/journal.pone.0267705.t005
DOI:
10.1371/journal.pone.0267705.t006
DOI:
10.1371/journal.pone.0267705.t007
DOI:
10.1371/journal.pone.0267705.s001
DOI:
10.1371/journal.pone.0267705.s002
DOI:
10.1371/journal.pone.0267705.s003
DOI:
10.1371/journal.pone.0267705.s004
DOI:
10.1371/journal.pone.0267705.r001
DOI:
10.1371/journal.pone.0267705.r002
DOI:
10.1371/journal.pone.0267705.r003
DOI:
10.1371/journal.pone.0267705.r004
DOI:
10.1371/journal.pone.0267705.r005
DOI:
10.1371/journal.pone.0267705.r006
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2022
detail.hit.zdb_id:
2267670-3
Bookmarklink