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  • American Physiological Society  (7)
  • 1975-1979  (7)
Type of Medium
Publisher
  • American Physiological Society  (7)
Person/Organisation
Language
Years
  • 1975-1979  (7)
Year
Subjects(RVK)
  • 1
    Online Resource
    Online Resource
    Cardiorespiratory responses following isoproterenol injection in rabbits
    American Physiological Society ; 1979
    In:  Journal of Applied Physiology Vol. 47, No. 2 ( 1979-08-01), p. 352-359
    Details
    In: Journal of Applied Physiology, American Physiological Society, Vol. 47, No. 2 ( 1979-08-01), p. 352-359
    Abstract: Receptor sites for the ventilatory response to isoproterenol were investigated in anesthetized rabbits with bolus injections in the common carotid artery (ia) and in the vena cava (iv). The delay from injection to the increase in ventilation (TVE) was significantly shorter following ia (1.5 s) compared to iv injections (about 5 s). The delay to the increase in heart rate (THR) was significantly shorter after iv (about 4.5 s) than after ia injections (12.5 s). When isoproterenol and NaCN injections were compared, there was no difference in TVE. Following carotid body resection, the VE response to isoproterenol was greatly reduced after iv and ia injections; however, THR was unaffected. In intact animals breathing 100% O2 the VE response to isoproterenol was significantly reduced with no change in TVE or in the heart rate response. We conclude that the ventilatory increase following the injection of isoproterenol is due primarily to direct stimulation of the carotid bodies.
    Type of Medium: Online Resource
    ISSN: 8750-7587 , 1522-1601
    URL: Article
    DOI: 10.1152/jappl.1979.47.2.352
    RVK:
    WA 15000
    RVK:
    XA 52094
    Language: English
    Publisher: American Physiological Society
    Publication Date: 1979
    detail.hit.zdb_id: 1404365-8
    SSG: 12
    SSG: 31
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  • 2
    Online Resource
    Online Resource
    Semiautomatic blood pressure monitor utilizing an electronic sphygmomanometer
    American Physiological Society ; 1977
    In:  Journal of Applied Physiology Vol. 43, No. 2 ( 1977-08-01), p. 379-381
    Details
    In: Journal of Applied Physiology, American Physiological Society, Vol. 43, No. 2 ( 1977-08-01), p. 379-381
    Abstract: A semicontinuous but noninvasive blood pressure monitoring system is described. It consists of a commercial electronic sphygmomanometer which utilizes a microphone under an occluding arm cuff to detect the Korotkoff sounds, a pressure transducer, and a simple gating circuit. The gate passes the cuff pressure signal to a recorder only when a proper Korotkoff sound is detected. The cuff is rapidly inflated to just above the anticipated systolic pressure, then deflated at a steady rate of 2–6 Torr/heartbeat. When diastolic pressure is passed, the cuff is fully deflated momentarily before repeating the cycle. Systolic and diastolic pressures can be recorded up to 3 or 4 times/min. Spurious signals are rejected by the electronics which process the output of the microphone. This allows the use of the system in experiments on exercising man and in environments where unwanted signals exist. The system offers greater versatility than commercial semiautomatic pressure monitors, at less than half the cost.
    Type of Medium: Online Resource
    ISSN: 8750-7587 , 1522-1601
    URL: Article
    DOI: 10.1152/jappl.1977.43.2.379
    RVK:
    WA 15000
    RVK:
    XA 52094
    Language: English
    Publisher: American Physiological Society
    Publication Date: 1977
    detail.hit.zdb_id: 1404365-8
    SSG: 12
    SSG: 31
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  • 3
    Online Resource
    Online Resource
    Ventilatory responses to acute CO2 exposure in the rat
    American Physiological Society ; 1978
    In:  Journal of Applied Physiology Vol. 45, No. 4 ( 1978-10-01), p. 611-618
    Details
    In: Journal of Applied Physiology, American Physiological Society, Vol. 45, No. 4 ( 1978-10-01), p. 611-618
    Type of Medium: Online Resource
    ISSN: 8750-7587 , 1522-1601
    URL: Article
    DOI: 10.1152/jappl.1978.45.4.611
    RVK:
    WA 15000
    RVK:
    XA 52094
    Language: English
    Publisher: American Physiological Society
    Publication Date: 1978
    detail.hit.zdb_id: 1404365-8
    SSG: 12
    SSG: 31
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  • 4
    Online Resource
    Online Resource
    Rheological properties of excised rabbit lung stiffened by repeated hyperinflation
    American Physiological Society ; 1979
    In:  Journal of Applied Physiology Vol. 47, No. 2 ( 1979-08-01), p. 360-368
    Details
    In: Journal of Applied Physiology, American Physiological Society, Vol. 47, No. 2 ( 1979-08-01), p. 360-368
    Abstract: Two rheological properties, stress adpatation (S) and hysteresis loop area (H), were studied in normal fresh rabbit lungs and in lungs stiffened by 3 hr repeated inflation at zero end-expiratory pressure. S was measured on the deflation limb at various volume levels ranging from 100 to 25% total lung capacity (TLC). H was obtained in another group of lungs before and after stiffening, for tidal volumes ranging from 5 to 30% TLC, at end-expiratory levels from 25 to 70% TLC. In stiff lung, S after deflation from TLC was biphasic (initial pressure rise, then a fall) whenever the starting pressure exceeded approximately 10 cmH2O. At low lung volumes (25% TLC) stress rose monotonically toward 10 cmH2O. Only monontonic adaptation has previously been reported for normal lung. Tidal H in stiff lungs was increased at all volume levels, occupying roughly 20% of a bounding pressure-volume rectangle, resembling that of normal lungs near TLC but twice that of normal loops at lower volumes. The results suggest that above an equilibrium or transition pressure around 10 cmH2O the alveolar lining in stiff lung may have film properties more resembling those of a viscous liquid, becoming solidlike below this pressure. Similar viscous liquid properties appear to exist on the inflation limb of normal lungs, and near TLC on their deflation limb.
    Type of Medium: Online Resource
    ISSN: 8750-7587 , 1522-1601
    URL: Article
    DOI: 10.1152/jappl.1979.47.2.360
    RVK:
    WA 15000
    RVK:
    XA 52094
    Language: English
    Publisher: American Physiological Society
    Publication Date: 1979
    detail.hit.zdb_id: 1404365-8
    SSG: 12
    SSG: 31
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  • 5
    Online Resource
    Online Resource
    Heart rate response to sympathetic stimulation before and after sodium pentobarbital
    American Physiological Society ; 1975
    In:  American Journal of Physiology-Legacy Content Vol. 228, No. 5 ( 1975-05-01), p. 1568-1574
    Details
    In: American Journal of Physiology-Legacy Content, American Physiological Society, Vol. 228, No. 5 ( 1975-05-01), p. 1568-1574
    Abstract: Heart rate response to electrical stimulation of the right stellate ganglion of vagotomized cats was studied before and after the administration of sodium pentobarbital. The increase and decrease of heart rate with the initiation and cessation of sympathetic stimulation could be accurately described by separate exponential time functions. The time constants of rise and decline, the maximum steady-state heart rate, and the time between cessation of stimulation and initial decrease of heart rate (lag) were functions of the frequency and voltage of stimulation. The main effects of sodium pentobarbital were: 1) to prolong the rise of heart rate by 20-30 percent (P smaller than 0.0001),2) to prolong the decay of heart rate by 36-56 percent (P smaller than 0.005), and 3) to decrease the resting heart rate. The effects were observed 10 min after administration of the drug and lasted at least 4 h.
    Type of Medium: Online Resource
    ISSN: 0002-9513
    URL: Article
    DOI: 10.1152/ajplegacy.1975.228.5.1568
    RVK:
    WA 15000
    RVK:
    XA 20060
    Language: English
    Publisher: American Physiological Society
    Publication Date: 1975
    detail.hit.zdb_id: 1477334-X
    detail.hit.zdb_id: 2065807-2
    detail.hit.zdb_id: 1477287-5
    detail.hit.zdb_id: 1477308-9
    detail.hit.zdb_id: 1477297-8
    detail.hit.zdb_id: 1477331-4
    detail.hit.zdb_id: 1477300-4
    detail.hit.zdb_id: 1477329-6
    SSG: 12
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  • 6
    Online Resource
    Online Resource
    Pulmonary interstitial and capillary pressures estimated from intra-alveolar fluid pressures
    American Physiological Society ; 1979
    In:  Journal of Applied Physiology Vol. 47, No. 3 ( 1979-09-01), p. 643-644
    Details
    In: Journal of Applied Physiology, American Physiological Society, Vol. 47, No. 3 ( 1979-09-01), p. 643-644
    Type of Medium: Online Resource
    ISSN: 8750-7587 , 1522-1601
    URL: Article
    DOI: 10.1152/jappl.1979.47.3.643
    RVK:
    WA 15000
    RVK:
    XA 52094
    Language: English
    Publisher: American Physiological Society
    Publication Date: 1979
    detail.hit.zdb_id: 1404365-8
    SSG: 12
    SSG: 31
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  • 7
    Online Resource
    Online Resource
    Respiratory mechanics in the anesthetized rat
    American Physiological Society ; 1978
    In:  Journal of Applied Physiology Vol. 45, No. 2 ( 1978-08-01), p. 255-260
    Details
    In: Journal of Applied Physiology, American Physiological Society, Vol. 45, No. 2 ( 1978-08-01), p. 255-260
    Abstract: Functional residual capacity (FRC) and pressure-volume (PV) curves of the lung, chest wall, and total respiratory system were studied in 15 anesthetized rats, weighing 307 +/- 10 (SE) g. Pleural pressure was estimated from the esophageal pressure measured with a water-filled catheter. The FRC determined by body plethysmograph was slightly and significantly larger than FRC determined from saline displacement of excised lungs. The difference may be accounted for by O2 uptake by lung tissue, escape of CO2 through the pleura, and abdominal gas. Paralysis in the prone position did not affect FRC, and abdominal gas content contributed only slightly to the FRC measured by body plethysmograph. Values of various pulmonary parameters (mean +/- SE) were as follows: residual volume, 1.26 +/- 0.13 ml; FRC, 2.51 +/- 0.20 ml; total lung capacity, 12.23 +/- 0.55 ml; compliance of the lung, 0.90 +/- 0.06 ml/cmH2O; chest wall compliance, 1.50 +/- 0.11 ml/cmH2O; and respiratory system compliance, 0.57 +/- 0.03 ml/cmH2O. The lung PV curve did not show a consistent change after the chest was opened.
    Type of Medium: Online Resource
    ISSN: 8750-7587 , 1522-1601
    URL: Article
    DOI: 10.1152/jappl.1978.45.2.255
    RVK:
    WA 15000
    RVK:
    XA 52094
    Language: English
    Publisher: American Physiological Society
    Publication Date: 1978
    detail.hit.zdb_id: 1404365-8
    SSG: 12
    SSG: 31
    Library Location Call Number Volume/Issue/Year Availability
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