In:
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, Vol. 49, No. 4 ( 2005-04), p. 1564-1566
Abstract:
A new natural TEM derivative with extended-spectrum β-lactamase activity, TEM-134, was identified in a ceftazidime-resistant clinical isolate of Citrobacter koseri . Compared to TEM-1, TEM-134 contains the following mutations: Q39K, E104K, R164H, and G238S. The bla TEM-134 gene was not transferable by conjugation and, apparently, was chromosomally encoded. Expression studies with Escherichia coli revealed efficient cefotaximase and ceftazidimase activity for TEM-134.
Type of Medium:
Online Resource
ISSN:
0066-4804
,
1098-6596
DOI:
10.1128/AAC.49.4.1564-1566.2005
Language:
English
Publisher:
American Society for Microbiology
Publication Date:
2005
detail.hit.zdb_id:
1496156-8
SSG:
12
SSG:
15,3
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