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Format: 1 online resource (906 pages)

ISBN: 9783319208770

Note: Intro -- Contents -- Editors and Contributors -- Introduction -- Part I Internationalization of Higher Education -- 1 Internationalization of Higher Education-What Can Research Add to the Policy Debate? [Overview Paper] -- 1 Introduction -- 2 Its Development -- 3 Impact -- 4 The Future -- 5 Input from the Papers -- References -- 2 Internationalization of Higher Education: Navigating Between Contrasting Trends -- 1 Introduction -- 2 Serving National Priorities Versus Operating in an International Setting -- 3 Government Steering Versus Institutional Autonomy -- 4 Increased Diversity Versus Harmonization -- 5 Competition Versus Collaboration -- 6 Intellectual Property Versus Intellectual Philanthropy -- 7 Concluding Remarks -- References -- 3 Balanced Mobility Across the Board--- A Sensible Objective? -- 1 Introduction -- 2 ``Balanced Mobility'' in the Bologna Process Context---Some Critical Reflections -- 2.1 The Origins -- 2.2 The Caveats -- 3 Why ``Balanced Mobility'' in 2007? -- 4 How Balanced Are EHEA Mobility Flows? -- 4.1 Balance Between Total Inflows and Outflows per Country -- 4.2 Balance Within EHEA -- 4.3 Balance with Non-EHEA Countries -- 5 More Balanced Flows---What Would This Entail? -- 6 Conclusions: Balanced Mobility---A Reasonable Objective? -- References -- 4 Challenges of Student Mobility in a Cosmopolitan Europe -- 1 Introduction -- 1.1 The CoSMiCE Project -- 2 Student Mobility in Europe -- 3 Impact Factors on European Student Mobility -- 3.1 Recognition -- 3.2 Restrictions and Fees -- 3.3 Financial Support -- 3.4 Social Support -- 3.5 Media Perception -- 3.6 Brain Drain and Brain Gain -- 4 Conclusions and Outlook -- Annex -- References -- 5 Redefining Internationalization at Home -- 1 Introduction -- 2 Accepted Definitions -- 2.1 Internationalization -- 2.2 Comprehensive Internationalization. , 2.3 Internationalization of the Curriculum -- 3 Contested Definitions -- 3.1 Internationalization at Home and Abroad -- 3.2 The OECD Definition of an Internationalized Curriculum -- 3.3 Campus Internationalization -- 4 Internationalization at Home -- 4.1 What Internationalization at Home Means -- 4.2 Internationalization at Home: The Emergence of the Concept -- 4.3 Existing Definition -- 4.4 Critiques and Appreciation -- 4.5 Continued Relevance of IaH as a Concept -- 4.6 New Definition of Internationalization at Home -- 5 Challenges for Policy and Implementation -- 6 Conclusion -- References -- 6 The Impact of Exposure to Diversity in the International University Environment and the Development of Intercultural Competence in Students -- 1 Internationalization as an Institutional Strategy for Intercultural Competence Development -- 2 Theory and Concepts -- 2.1 The Contact Hypothesis for Intergroup Contact as a Theoretical Framework -- 2.2 Defining Intercultural Competence -- 2.3 Measuring the Development of Intercultural Competence -- 2.4 A Tentative Model for Intercultural Competence Development -- 3 The University Case -- 4 Method -- 5 Results -- 5.1 Development of Intercultural Competence After Nine Months of Study -- 5.2 Polarization -- 5.3 Perception of the Own Level of Intercultural Competence -- 5.4 Impact of the Social Environment -- 6 Conclusions -- 7 Discussion -- References -- 7 Internationalisation as a Lever for Change: The Case of Italy -- 1 Introduction -- 2 Systemic Tradition of Central Planning and Uniformity -- 3 Italian Higher Education Response to the Bologna Process -- 4 Internationalisation as a Lever for Change -- 5 Institutional Responses -- 6 Patterns of Convergence and Divergence -- 7 Dual Accountability -- 8 Isomorphic Tendencies -- 9 Conclusions -- References. , 8 Becoming Bologna Capable: Strategic Cooperation and Capacity Building in International Offices in Kazakhstani HEIs -- 1 Introduction -- 2 Theoretical Perspectives -- 2.1 Internationalization of Higher Education -- 2.2 Institutional Change -- 2.3 Capacity Building and Professional Development -- 3 Kazakhstan Context -- 4 Methodology -- 5 Results -- 5.1 What Forms of Strategic Cooperation Are Considered Necessary for Effective Engagement in Achieving Bologna Process Goals? -- 5.1.1 International Dimension -- 5.1.2 National Dimension -- 5.1.3 Intra-institutional Dimension -- 5.2 Do International Offices Have the Capacity to Engage Effectively in Strategic Cooperation for Bologna Process Goals? -- 5.3 What Do International Office Staff Perceive as Necessary to Develop Their Professional Capacity to Achieve These Goals? -- 6 Discussion -- 6.1 The Potential for IO Leadership for Comprehensive Internationalization -- 6.2 The Need to Increase IO Capacity for Bologna Process in Times of Institutional Change -- 6.3 Making Professional Development for International Office Staff a Priority -- 7 Conclusion -- References -- 9 Internationalization Strategies and Policies in Second-Tier Higher Education Institutions -- 1 Introduction -- 2 Context -- 2.1 Internationalization in Higher Education -- 2.2 Second-Tier Higher Education Institutions -- 2.3 Internationalization in Second Tier Institutions -- 3 Case Studies: Israel, the Netherlands and Canada -- 3.1 Israel -- 3.1.1 The Israeli Higher Education System -- 3.1.2 Internationalization at Second-Tier Israeli Higher Education Institutions -- 3.2 Netherlands -- 3.2.1 The Dutch Higher Education System -- 3.2.2 Internationalization at Second-Tier Dutch Higher Education Institutions -- 3.3 Canada -- 3.3.1 The Canadian Higher Education System. , 3.3.2 Internationalization at Second-Tier Canadian Higher Education Institutions -- 4 Discussion and Conclusion -- References -- Part II Higher Education Financing andGovernance -- 10 Background Note for the Section on Financing and Governance [Overview Paper] -- References -- 11 Strategies for Efficient Funding of Universities in Europe -- 1 Methodology -- 2 Funding of Higher Education Institutions -- 2.1 Income Structures -- 2.2 Public Funding Modalities -- 3 Performance-Based Funding -- 3.1 Funding Formulae -- 3.2 Performance Contracts -- 3.3 Overview of Performance Elements in Block Grant Allocation -- 3.4 Effects of Performance-Based Funding on Higher Education Systems -- 4 Funding for Excellence -- 4.1 Characteristics of Excellence Schemes in Higher Education -- 4.2 Impact on Institutional Profiling and Restructuring -- 4.3 The Role of the University Leadership -- 4.4 Exit Strategies for Institutions and Systems -- 5 Efficiency Measures -- 5.1 Types of Efficiency Measures -- 5.2 Enabling Frameworks -- 6 Conclusions -- References -- 12 Financing Research Universities in Post-communist EHEA Countries -- 1 Introduction -- 2 Historical Overview -- 3 Comparative Study of Some HEIs from Different Countries -- 3.1 A Detailed Insight into the Hungarian R& -- D Financing in Higher Education -- 4 Conclusion and Recommendations -- References -- 13 Policy Incentives and Research Productivity in the Romanian Higher Education. An Institutional Approach -- 1 Introduction -- 2 Institutional Arrangements Within Romanian Higher Education -- 2.1 The Problem of Increasing Research Productivity -- 2.2 The Academic Career -- 2.3 The Quality Assurance Process -- 2.4 The University Classification Exercise and the Introduction of Performance Criteria -- 2.5 The New Public Funding Mechanism -- 3 Methodology -- 3.1 Research Productivity and Its Impact -- 3.2 Methods. , 3.3 Data Analysis and Results -- 4 Discussion -- 5 Conclusion -- Acknowledgements -- References -- 14 Patterns of Funding Internationalisation of Higher Education. A Conceptual Framework for the Study of Internationalisation -- 1 Introduction -- 2 A Conceptual Framework for the Study of Patterns of Funding of Internationalisation -- 2.1 Sources of Funding Internationalisation -- 2.2 Types of Internationalisation Activities Funded (Motivations) -- 2.3 Types of Internationalisation Activities Funded (Geographic Scope) -- 2.4 Instruments of Funding -- 2.5 Funding Strategies -- 3 Conclusions -- References -- 15 The Evolving Landscape of South-East Asian Higher Education and the Challenges of Governance -- 1 Introduction -- 2 The Changing Landscape of Higher Education in South-East Asia -- 2.1 Massification -- 2.2 Diversification -- 2.3 Marketization -- 2.4 Internationalization -- 3 Restructuring Higher Education and the New Modes of Governance and Finance -- 3.1 Governance Structures -- 3.2 Finance and Budget -- 3.3 Human Resource Management -- 3.4 Academic Matters -- 4 Quality Assurance -- 5 Regional Integration and the Efforts on Higher Education Harmonization -- 6 Reform, Regionalization, and the Challenges for Future Development -- Acknowledgements -- References -- Part III Excellence and Diversification of HigherEducation Institutions' Missions -- 16 Seeking Excellence, Practicing Rankings, and Aiming at Diversification of Higher Education Institutions' Mission in the European Higher Education Area [Overview Paper] -- 1 Introduction -- 2 Excellence -- 3 Diversification -- 4 Rankings -- 5 Concluding Remarks -- References -- 17 Excellence-Driven Policies and Initiatives in the Context of Bologna Process: Rationale, Design, Implementation and Outcomes -- 1 Introduction -- 2 Rationale of Excellence-Driven Policies and Initiatives. , 3 Design of Excellence-Driven Policies and Initiatives.

Additional Edition: Print version: Curaj, Adrian The European Higher Education Area Cham : Springer International Publishing AG,c2015 ISBN 9783319187679

Language: English

Keywords: Electronic books. ; Electronic books. ; Electronic books. ; Conference papers and proceedings.

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Format: 1 online resource (xiii, 405 pages)

ISBN: 9780203995549 , 9781134882694 , 9781134882731 , 9781134882748

Content: BOOK COVER; HALF-TITLE; TITLE; COPYRIGHT; CONTENTS; FIGURES; TABLES; CONTRIBUTORS; PREFACE; ACKNOWLEDGEMENTS; 1 INDUSTRIALIZATION AND REGIONAL DEVELOPMENT; 2 FORDIST AND POST-FORDIST INTERNATIONAL DIVISION OF LABOR AND MONETARY REGIMES; 3 FORDISM AND POST-FORDISM: A CRITICAL REFORMULATION; 4 FLEXIBLE SPECIALIZATION VERSUS POST-FORDISM: THEORY, EVIDENCE, AND POLICY IMPLICATIONS; 5 THE JAPANESE MODEL OF POST-FORDISM; 6 THE REVITALIZATION OF MASS PRODUCTION IN THE COMPUTER AGE; 7 TECHNOLOGICAL TRAJECTORIES AND THE CLASSICAL REVIVAL IN ECONOMICS.

Note: Includes bibliographical references (pages 349-401) and index

Additional Edition: ISBN 9780415087520

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DOI: 10.4324/9780203995549

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Format: 1 online resource (374 pages)

ISBN: 9789811511851 , 9811511853

Content: This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.

Note: Includes index. , PART I: Basic Science of Pulmonary Development and Pulmonary Arterial Disease -- 1 Perspective for Part I -- 2 The alveolar stem cell niche of the mammalian lung -- 3 Lung development and Notch signalling -- 4 Specialized smooth muscle cell progenitors in pulmonary hypertension -- 5 Diverse Pharmacology of Prostacyclin Mimetics: Implications for Pulmonary Hypertension -- 6 Endothelial-to-mesenchymal transition in pulmonary hypertension -- 7 Extracellular vesicles, MicroRNAs and Pulmonary Hypertension -- 8 Roles of Tbx4 in the lung mesenchyme for airway and vascular development -- 9 A lacZ reporter transgenic mouse line revealing the development of pulmonary artery -- 10 Roles of stem cell antigen-1 in the pulmonary endothelium -- 11 Morphological characterization of pulmonary microvascular disease in bronchopulmonary dysplasia caused by hyperoxia in newborn mice -- 12 Involvement of CXCR4 and stem cells in a rat model of pulmonary arterial hypertension -- 13 Ca2+ signal through inositol trisphosphate receptors for cardiovascular development and pathophysiology of pulmonary arterial hypertension -- PART II: Abnormal pulmonary circulation in the developing lung and heart -- 14 Perspective for Part II -- 15 Pathophysiology of Pulmonary Circulation in Congenital Heart Disease -- 16 Development of Novel Therapies for Pulmonary Hypertension by Clinical Application of Basic Research -- 17 Using Patient-Specific Induced Pluripotent Stem Cells to Understand and Treat Pulmonary Arterial Hypertension -- 18 Modeling pulmonary arterial hypertension using induced pluripotent stem cells -- 19 Dysfunction and restoration of endothelial cell communications in Pulmonary Arterial Hypertension: Therapeutic implications -- 20 Inflammatory Cytokines in the Pathogenesis of Pulmonary Arterial Hypertension -- 21 Genotypes and Phenotypes of Chinese Pediatric Patients with Idiopathic and Heritable Pulmonary Arterial Hypertension- Experiences from A Single Center -- 22 Fundamental Insight into Pulmonary Vascular Disease : Perspectives from Pediatric PAH in Japan -- 23 Risk stratification in paediatric pulmonary arterial hypertension -- 24 The Adaptive Right Ventricle in Eisenmenger Syndrome: Potential Therapeutic Targets for Pulmonary Hypertension -- 25 Impaired right coronary vasodilator function in pulmonary hypertensive rat assessed by in vivo synchrotron microangiography -- 26 Relationship between mutations in ENG and ALK1 gene and the affected organs in hereditary hemorrhagic telangiectasia -- 27 A genetic analysis for patients with pulmonary arterial hypertension -- 28 Evaluation and visualization of right ventricle using three dimensional echocardiography -- 29 Pulmonary hypertension associated with post-operative Tetralogy of Fallot -- 30 Microscopic Lung Airway Abnormality and Pulmonary Vascular Disease Associated with Congenital Systemic to Pulmonary Shunt -- 31 Respiratory syncytial virus infection in infants with heart and lung diseases -- PART III: Ductus arteriosus: bridge over troubled vessels -- 32 Perspective for Part III -- 33 The ductus arteriosus, a vascular outsider, in relation to the pulmonary circulation -- 34 Molecular, genetic, and pharmacological modulation of the ductus arteriosus: KATP channels as novel drug targets -- 35 New mediators in the biology of the ductus arteriosus: Lessons from the chicken embryo -- 36 Constriction of the Ductus Arteriosus with KATP Channel Inhibitors -- 37 New insights on how to treat patent ductus arteriosus -- 38 Antenatal Administration of Betamethasone Contributes to Intimal thickening of the Ductus Arteriosus -- 39 Prostaglandin E-EP4-mediated fibulin-1 up-regulation plays a role in intimal thickening of the ductus arteriosus -- 40 Transcriptional profiles in the chicken ductus arteriosus during hatching -- 41 Inhibition of Cyclooxygenase Contracts Chicken Ductus Arteriosus -- 42 Prostaglandin E2 receptor EP4 inhibition constricts the rat ductus arteriosus -- 43 Dilatation of the Ductus Arteriosus by Diazoxide in Fetal and Neonatal Rats -- 44 The Effect of Long-term Administration of Plostaglandin E1 on Morphological Changes in Ductus Arteriosus -- 45 Significance of SGK1 as a protein kinase transcriptionally regulated by ALK1 signaling in vascular endothelial cells -- 46 Fabrication of Implantable Human Arterial Graft by Periodic Hydrostatic Pressure -- 47 Optimum preparation of Candida albicans cell wall extra (CAWE) for the mouse model of Kawasaki disease -- PART IV: Development and Regeneration of the Cardiovascular System -- 48 Perspective for Part IV -- 49 Advances in the second heart field -- 50 Novel cardiac progenitors for all components of the heart except for the right ventricle -- 51 Regional and TBX5-dependent gene expression in the atria: Implications for pulmonary vein development and atrial fibrillation -- 52 The Endocardium as a Master Regulator of Ventricular Trabeculation -- 53 The Role of Alternative mRNA Splicing in Heart Development -- 54 Progress in the Generation of Multiple Lineage Human-iPSC-derived 3D Engineered Cardiac Tissues for Cardiac Repair -- 55 Quantification of contractility in stem cell derived cardiomyocytes -- 56 A neurotrophic factor receptor GFRA2, a specific surface antigen for cardiac progenitor cells, regulates the process of myocardial compaction -- 57 Cardiac cell specification and differentiation by the defined factors -- 58 A Temporo-Spatial Regulation of Sema3c is Essential for Interaction of Progenitor Cells during Cardiac Outflow Tract Development -- 59 Spatiotemporally restricted developmental alterations in the anterior and secondary heart fields cause distinct conotruncal heart defects -- 60 Significance of transcription factors in the mechanisms of great artery malformations -- 61 The different c-kit expression in human induced pluripotent stem (iPS) cells between with feeder cells and without feeder cells -- 62 Establishment of induced pluripotent stem cells from immortalized B cell lines and their differentiation into cardiomyocytes -- 63 Establishment of an in vitro LQT3 model, using induced pluripotent stem cells from LQT3 patient-derived cardiomyocytes -- 64 Genetic Assessments for clinical courses of Left ventricle noncompaction -- 65 Elucidating the pathogenesis of congenital heart disease in the era of next-generation sequencing.

Additional Edition: Print version: Nakanishi, Toshio. Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension. Singapore : Springer, ©2020 ISBN 9789811511844

Language: English

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