In:
PAIN Reports, Ovid Technologies (Wolters Kluwer Health), Vol. 2, No. 6 ( 2017-11), p. e620-
Abstract:
Patient information leaflets on pain medication primarily list side effects while positive effects and action mechanisms remain underrepresented. Nocebo research has shown that negative instructions can lower analgesic effects. Objectives: Research on information leaflets and their influence on mood, memory of side effects, and intake behavior of healthy participants is needed. Methods: To determine the ratio of positive to negative phrases, 18 information leaflets of common, over-the-market analgesics were examined of which 1 was selected. In a randomized, controlled study design, 18 healthy participants read this leaflet while 18 control group participants read a matched, neutral leaflet of an electrical device. Collected data concerned the recall of positive and negative contents, mood, anxiety, and the willingness to buy and take the drug. Results: All examined leaflets listed significantly more side effects than positive effects (t 17 = 5.82, P 〈 0.01). After reading the analgesic leaflet, participants showed a trend towards more negative mood ( F 1,34 = 3.78, P = 0.06, η p 2 = 0.1), a lower intention to buy [χ 2 (1, n = 36) = 12.5, P 〈 0.01], a higher unwillingness to take the medication [χ 2 (1, n = 36) = 7.2, P 〈 0.01], and even a greater recall for side effects than positive effects (t 17 = 7.47, P 〈 0.01). Conclusion: Reading the patient information leaflets can increase fear and lower the intention to buy and the willingness to take a pain medication.
Type of Medium:
Online Resource
ISSN:
2471-2531
DOI:
10.1097/PR9.0000000000000620
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2017
detail.hit.zdb_id:
2898347-6
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