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Umfang: 1 Online-Ressource (x, 358 Seiten)

Ausgabe: Online-Ausgabe Springer ebook collection. Medicine 2005-2008

ISBN: 9788847003521

Weitere Ausg.: Reproduktion von Magnetic resonance angiography 2005

Weitere Ausg.: Erscheint auch als Druck-Ausgabe ISBN 978-88-470-0266-1

Weitere Ausg.: ISBN 88-470-0266-4

Sprache: Englisch

Fachgebiete: Medizin

Schlagwort(e): Magnetresonanzangiografie

DOI: 10.1007/b138651

URL: Volltext  (URL des Erstveröffentlichers)

URL: Volltext

URL: Volltext  (lizenzpflichtig)

URL: Cover

Mehr zum Autor: Schneider, Günther

UID:

Umfang: 1 Online-Ressource (XVIII, 412 S.) , zahlr. Ill.

Ausgabe: 2. ed.

Ausgabe: Online-Ausgabe Springer ebook collection. Medicine 2005-2008

ISBN: 9788847004696

Weitere Ausg.: Erscheint auch als Druck-Ausgabe ISBN 978-88-470-0335-4

Weitere Ausg.: ISBN 88-470-0335-0

Sprache: Englisch

Fachgebiete: Medizin

Schlagwort(e): Leberkrankheit ; Kernspintomografie

DOI: 10.1007/88-470-0469-1

URL: Volltext

URL: Volltext

URL: Volltext  (lizenzpflichtig)

URL: Cover

URL: Inhaltstext

Mehr zum Autor: Schneider, Günther

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Umfang: 1 Online-Ressource , v.: digital

Ausgabe: Online_Ausgabe Berlin, Heidelberg Springer-Verlag 2007 Springer ebook collection / Chemistry and Materials Science 2005-2008 Sonstige Standardnummer des Gesamttitels: 041171-1

ISBN: 9783540712718 , 9783540712732

Weitere Ausg.: Reproduktion von Quality Assurance for Chemistry and Environmental Science 2007

Sprache: Englisch

URL: Volltext

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Umfang: 1 Online-Ressource (552 p.) , 254 b&w, ill

ISBN: 1847558003 , 9781847558008

Anmerkung: This book highlights the importance of smart material science in the 21st century, From the nanoscale to the macroscopic scale, intelligent materials are triggering a response across both dimensions and scientific disciplines! World class, leading experts in the fields of chemistry, physics and engineering have contributed to Intelligent Materials, highlighting the importance of smart material science in the 21st century. In this exceptional text the expertise of specialists across the globe is drawn upon to present a truly interdisciplinary outline of the topic. Covering both a bottom-up chemical, and top-down engineering approach to the design of intelligent materials the Editors of the book are bridging a vital gap between various scientific authorities. The influence of current research in this field on future technology is undisputed and potential applications of intelligent materials span nanoscience, nano technology, medicine, engineering, biotechnology, pharmaceutical and many other industries. This is an authoritative introduction to the most recent developments in the area, which will provide the reader with a better understanding of the almost unlimited opportunities in the progress and design of new intelligent materials. An indispensable reference for anyone contemplating working in the field! Comments on this book! "This will be the starting point for all researchers looking for industrial solutions involving smart materials. Congratulations to the Editors for providing such a vast and interdisciplinary book." P.-G de Gennes, France Prix Nobel de Physic 1991

Sprache: Englisch

Fachgebiete: Chemie/Pharmazie , Physik

Schlagwort(e): Intelligenter Werkstoff ; Aufsatzsammlung ; Electronic books

URL: Volltext

URL: Volltext  (Deutschlandweit zugänglich)

URL: Volltext  (Deutschlandweit zugänglich)

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Umfang: XX, 273 S. , Ill.

ISBN: 025202057X

Serie: The Working class in American history

Inhalt: In Trade Unions and Community Dorothee Schneider argues that German unions played a vital role in building community for German immigrants in North America. More than other organizations such as churches or regional groups, Schneider maintains, trade unions were in the best position to build community in a new, rapidly changing industrial society. Why were the unions so well suited to the development of the German-American working class and its integration into North American society and politics? What was the effect of the trade unions' central role on the community as a whole? Did these unions carry their community-building role into the American trade union movement in general? To answer these questions, Schneider focuses on German-American skilled workers, portraying a group of immigrants who brought from Europe not just their pre-industrial traditions but also a wealth of experience in industrialized settings and a diverse political culture. Examining bakers, brewery workers, and cigar makers, she highlights the origins of the political culture of the American immigrant working class in a new way. Schneider argues that, in spite of the contradictory interests of traditionalists, political progressives, and assimilationists, German-American workers favored a centralized craft unionism and thus became backers of Samuel Gompers's American Federation of Labor.

Anmerkung: Teilw. zugl.: München, Univ., Diss., 1983 u.d.T.: Schneider, Dorothee: Gewerkschaft und Gemeinschaft

Sprache: Englisch

Fachgebiete: Geschichte , Wirtschaftswissenschaften , Ethnologie

Schlagwort(e): New York, NY ; Arbeiterbewegung ; Deutscher Einwanderer ; Geschichte 1870-1900 ; New York, NY ; Deutsche ; Arbeiter ; Soziale Integration ; Gewerkschaft ; Geschichte 1870-1900 ; Hochschulschrift

URL: Inhaltsverzeichnis

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Umfang: 1 Online-Ressource (356 p.) , 89 b&w, ill

ISBN: 1847558879 , 9781847558879

Anmerkung: Focuses on chemoinformatics approaches applicable to virtual screening of very large available collections of chemical compounds to identify novel biologically active molecules, Chemoinformatics is broadly a scientific discipline encompassing the design, creation, organization, management, retrieval, analysis, dissemination, visualization and use of chemical information. It is distinct from other computational molecular modeling approaches in that it uses unique representations of chemical structures in the form of multiple chemical descriptors; has its own metrics for defining similarity and diversity of chemical compound libraries; and applies a wide array of statistical, data mining and machine learning techniques to very large collections of chemical compounds in order to establish robust relationships between chemical structure and its physical or biological properties. Chemoinformatics addresses a broad range of problems in chemistry and biology; however, the most commonly known applications of chemoinformatics approaches have been arguably in the area of drug discovery where chemoinformatics tools have played a central role in the analysis and interpretation of structure-property data collected by the means of modern high throughput screening. Early stages in modern drug discovery often involved screening small molecules for their effects on a selected protein target or a model of a biological pathway. In the past fifteen years, innovative technologies that enable rapid synthesis and high throughput screening of large libraries of compounds have been adopted in almost all major pharmaceutical and biotech companies. As a result, there has been a huge increase in the number of compounds available on a routine basis to quickly screen for novel drug candidates against new targets/pathways. In contrast, such technologies have rarely become available to the , academic research community, thus limiting its ability to conduct large scale chemical genetics or chemical genomics research. However, the landscape of publicly available experimental data collection methods for chemoinformatics has changed dramatically in very recent years. The term "virtual screening" is commonly associated with methodologies that rely on the explicit knowledge of three-dimensional structure of the target protein to identify potential bioactive compounds. Traditional docking protocols and scoring functions rely on explicitly defined three dimensional coordinates and standard definitions of atom types of both receptors and ligands. Albeit reasonably accurate in many cases, conventional structure based virtual screening approaches are relatively computationally inefficient, which has precluded them from screening really large compound collections. Significant progress has been achieved over many years of research in developing many structure based virtual screening approaches. This book is the first monograph that summarizes innovative applications of efficient chemoinformatics approaches towards the goal of screening large chemical libraries. The focus on virtual screening expands chemoinformatics beyond its traditional boundaries as a synthetic and data-analytical area of research towards its recognition as a predictive and decision support scientific discipline. The approaches discussed by the contributors to the monograph rely on chemoinformatics concepts such as: -representation of molecules using multiple descriptors of chemical structures -advanced chemical similarity calculations in multidimensional descriptor spaces -the use of advanced machine learning and data mining approaches for building quantitative and predictive structure activity models -the use of chemoinformatics methodologies for the analysis of drug-likeness and property prediction , -the emerging trend on combining chemoinformatics and bioinformatics concepts in structure based drug discovery The chapters of the book are organized in a logical flow that a typical chemoinformatics project would follow - from structure representation and comparison to data analysis and model building to applications of structure-property relationship models for hit identification and chemical library design. It opens with the overview of modern methods of compounds library design, followed by a chapter devoted to molecular similarity analysis. Four sections describe virtual screening based on the using of molecular fragments, 2D pharmacophores and 3D pharmacophores. Application of fuzzy pharmacophores for libraries design is the subject of the next chapter followed by a chapter dealing with QSAR studies based on local molecular parameters. Probabilistic approaches based on 2D descriptors in assessment of biological activities are also described with an overview of the modern methods and software for ADME prediction. The book ends with a chapter describing the new approach of coding the receptor binding sites and their respective ligands in multidimensional chemical descriptor space that affords an interesting and efficient alternative to traditional docking and screening techniques. Ligand-based approaches, which are in the focus of this work, are more computationally efficient compared to structure-based virtual screening and there are very few books related to modern developments in this field. The focus on extending the experiences accumulated in traditional areas of chemoinformatics research such as Quantitative Structure Activity Relationships (QSAR) or chemical similarity searching towards virtual screening make the theme of this monograph essential reading for researchers in the area of computer-aided drug discovery. However, due to its generic data- , analytical focus there will be a growing application of chemoinformatics approaches in multiple areas of chemical and biological research such as synthesis planning, nanotechnology, proteomics, physical and analytical chemistry and chemical genomics

Sprache: Englisch

Fachgebiete: Chemie/Pharmazie

Schlagwort(e): Computational chemistry ; Struktur-Aktivitäts-Beziehung ; QSAR ; Screening ; Aufsatzsammlung

URL: Volltext

UID:

Umfang: 1 Online-Ressource (XV, 625 S.) , graph. Darst.

ISBN: 9780387758701

Weitere Ausg.: Erscheint auch als Druck-Ausgabe ISBN 0-387-74574-2

Weitere Ausg.: Erscheint auch als Druck-Ausgabe ISBN 978-0-387-74574-9

Sprache: Englisch

Fachgebiete: Wirtschaftswissenschaften

Schlagwort(e): Politische Ökonomie ; Kollektiventscheidung ; Aufsatzsammlung

DOI: 10.1007/978-0-387-75870-1

URL: Volltext  (URL des Erstveröffentlichers)

Mehr zum Autor: Schneider, Friedrich 1949-

UID:

Umfang: 1 Online-Ressource

Serie: eHRAF World Cultures

Inhalt: This collection of 26 documents concerns the Yapese, who speak an Eastern Malayo-Polynesian language and occupy the westernmost of the Caroline Islands in Micronesia. The earliest documents in the collection, translated from German, were published between 1873 and 1917 and cover the time period of 1865 to 1910. The accounts are by explorers, government officials, missionaries, natural scientists, and travelers. There is one Spanish source and a German translation of Russian explorer's diary. Topics include religion, geography, music, poetry, dance, funerals, and money. Documents from the American period and onwards, starting in 1947, include a general ethnography, politics, courtship and marriage, dispute settlement, food, and post-colonial changes. Yap was under Spanish control from 1871 to 1899, German control from 1899 to 1914, Japanese control from 1914 to 1945, and American control from 1945 to 1985, after which it became part of an independent state (Yap State) in the Federated States of Micronesia

Anmerkung: Yap - Wilhelm Müller - 1917 -- - Political organization, supernatural sanctions and the punishment for incest on Yap - David M. Schneider - 1957 -- - Traditional coconut culture in Yap - S. Bert Ogata - 1960 -- - Culture summary: Yapese - Sherwood Galen Lingenfelter and Ian Skoggard (synopsis and indexing notes) - 2006 -- - The Micronesians of Yap and their depopulation: report of the Peabody Museum Expedition to Yap Island, Micronesia, 1947-1948 - Edward E. Hunt, Jr., David M. Schneider, Nathaniel R. Kidder, and William D. Stevens - 1949 -- - The Carolines Island Yap - Father Salesius - 1906 -- - Yap kinship terminology and kin groups - David M. Schneider - 1953 -- - The Carolines Island Yap or Guap, according to the reports of Alfred Tetens and Johann Kubary - Alfred Tetens and Johann Kubary ; prepared by Dr. E. Gräffe - 1873 -- , - Ethnographic contributions concerning the Caroline Islands of Yap - Arno Senfft - 1903 -- - Abortion and depopulation on a Pacific Island - David M. Schneider - 1955 -- - The stone money of Yap - Inez de Beauclair - 1963 -- - Political leadership and culture change in Yap - Sherwood Galen Lingenfelter - 1972 [1975 copy] -- - The legal customs of the Yap natives - Arno Senfft - 1907 -- - Concerning the Carolines Island of Yap - G. Volkens - 1901 -- - Western Carolines: the island of Yap - José Montes de Oca - 1893 -- - Some remarks on the music, poetry and dance of the people of Yap - L. Born - 1903 -- - The money of the Yapese - Arno Senfft - 1901 -- - Funeral obsequies on Yap (Western Carolines) - L. Born - 1903 -- - The island of Yap: anthropological sketches from the diary of N. N. Miklkukha-Maklai - N. N. Miklucho-Maclay - 1878 -- - Religious views and customs of the inhabitants of Yap (German South Seas) - Sixtus Walleser - 1913 -- - Yap eating classes: a study of structure and communitas - Sherwood G. Lingenfelter - 1979 -- , - In the court or in the village?: settling disputes in Yap: 1950-1979 - Sherwood G. Lingenfelter - 1991 -- - Courtship and marriage on Yap: Budweiser, U-drives, and rock guitars - Sherwood G. Lingenfelter - 1993 -- - Emic structure and decision-making in Yap - Sherwood G. Lingenfelter - 1977 -- - The demystification of Yap: dialectics of culture on a Micronesian island - David Labby - 1976 -- - Taro, fish, and funerals: transformations in the Yapese cultural topography of wealth - by James Arthur Egan - 1998 [2005 copy] -- - Production and circulation of food in Yap - James A. Egan, Michael L. Burton, and Karen L. Nero - [n.d.]

Sprache: Englisch

Fachgebiete: Ethnologie

Schlagwort(e): Yap ; Bevölkerung

URL: Volltext

UID:

Umfang: 149 S. , Ill., Kt.

ISBN: 3825878368

Serie: Encounters /Begegnungen 5

Anmerkung: Beitr. teilw. engl., teilw. franz.

Sprache: Englisch

Fachgebiete: Geschichte , Ethnologie

Schlagwort(e): Deutschland ; Kolonialismus ; Kamerun ; Kollektives Gedächtnis ; Geschichte ; Konferenzschrift

URL: Inhaltsverzeichnis

Mehr zum Autor: Michels, Stefanie 1971-

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Umfang: 139 S.

ISBN: 0141187980 , 9780141187983

Originaltitel: Der Mauerspringer

Sprache: Englisch

Schlagwort(e): Fiktionale Darstellung

Mehr zum Autor: Schneider, Peter 1940-