Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
Type of Medium
Language
  • 1
    Online Resource
    Online Resource
    Elsevier BV ; 1981
    In:  Journal of Non-Crystalline Solids Vol. 46, No. 3 ( 1981-12), p. 247-257
    In: Journal of Non-Crystalline Solids, Elsevier BV, Vol. 46, No. 3 ( 1981-12), p. 247-257
    Type of Medium: Online Resource
    ISSN: 0022-3093
    Language: English
    Publisher: Elsevier BV
    Publication Date: 1981
    detail.hit.zdb_id: 1500501-X
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Online Resource
    Online Resource
    Elsevier BV ; 1987
    In:  Journal of the Less Common Metals Vol. 127 ( 1987-1), p. 167-173
    In: Journal of the Less Common Metals, Elsevier BV, Vol. 127 ( 1987-1), p. 167-173
    Type of Medium: Online Resource
    ISSN: 0022-5088
    Language: English
    Publisher: Elsevier BV
    Publication Date: 1987
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Online Resource
    Online Resource
    CSIRO Publishing ; 2008
    In:  Reproduction, Fertility and Development Vol. 20, No. 1 ( 2008), p. 136-
    In: Reproduction, Fertility and Development, CSIRO Publishing, Vol. 20, No. 1 ( 2008), p. 136-
    Abstract: Cloned bovine embryos have been shown to display deviations in gene expression of trophectodermal (TE) lineage-specific transcription factors, including Cdx2, Errβ, Eomes, Mash2, and Hand1. Misregulation of these genes in the early TE has been implicated to play a causal role in abnormal placental formation and fetal loss. Because suboptimal in vitro culture conditions fail to support development beyond hatching, very little is known about regulation of peri-attachment bovine embryo development. Trophectodermal-derived bovine cell lines, such as the CT-1 cell line produced by Talbot and colleagues (Talbot et al. 2000 Biol. Reprod. 62, 235–247) could prove beneficial for understanding how regulatory factors govern early bovine TE development. The CT-1 cell line has been cultured continuously for over 2 years and appears morphologically similar to primary bovine TE outgrowths. Furthermore, these cells produce interferon τ, a cytokine unique to the early bovine TE. The objective of this study was to develop a gene expression profile of selected developmental genes that play a potential role in commitment to the TE fate, maintenance of multipotency, or differentiation into a binucleate phenotype. The CT-1 colonies were initially expanded on gamma-irradiated STO cells at 37°C and 5% CO2 and passaged weekly. Cells were cultured in DMEM supplemented with 10% fetal bovine serum and 1 mm sodium pyruvate and were passaged whenever colony edges touched. Cultures designated for RNA extraction and RT-PCR were then passaged into collagen-coated flasks or Cellbind® flasks (Corning, Lowell, MA, USA) at an average dilution of 1:4 for at least 6 feeder-free passages. Feeder-free culture at 37°C and 8.5% CO2 was optimal for adherence and growth. There were no observable differences in morphology, adherence, or growth rate between CT-1 cells grown on collagen film or a Cellbind® surface. The RT-PCR results indicate that the transcription factor Cdx2, which is homologous to the mouse master TE regulator, is abundantly expressed, whereas pluripotency specific Oct4 is weakly expressed. However, pluripotency specific transcription factors Nanog and Sox2 were undetectable. Transcription factors Eomes, Ets2, Errβ, and Id2, which may be required for proper bovine trophoblast elongation and developmental potential, were also expressed. Hand1 mRNA, a basic helix-loop-helix transcription factor that directs mouse trophoblast cells to differentiate into a giant cell phenotype, was also present and may play a role in binucleate cell formation. Together the data indicate that the CT-1 cell line can be utilized as a permissive cell line for studying transcriptional control of key TE regulatory factors that define the bovine TE lineage and allow better interpretation of gene expression data collected from assisted reproductive technology-derived embryos.
    Type of Medium: Online Resource
    ISSN: 1031-3613
    Language: English
    Publisher: CSIRO Publishing
    Publication Date: 2008
    SSG: 12
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Online Resource
    Online Resource
    Walter de Gruyter GmbH ; 2022
    In:  Journal of Osteopathic Medicine Vol. 122, No. 11 ( 2022-10-26), p. 581-586
    In: Journal of Osteopathic Medicine, Walter de Gruyter GmbH, Vol. 122, No. 11 ( 2022-10-26), p. 581-586
    Abstract: Asthma is the most common chronic disease affecting children in the United States. Goals for asthma management include symptom control, the ability to maintain a normal activity level, and minimizing adverse events. Objectives The objective of this study is to analyze the number of children with asthma that are permitted to carry medications at school and without an asthma action plan. Methods In this study, we analyzed the Center for Disease Control and Prevention (CDC) Asthma Call-back Survey (ACBS) to assess the prevalence of children in school allowed to carry medication and with asthma action plans. Utilizing the sampling weights provided, we estimated population prevalence by age group and urbanicity. Results Results showed that, overall, 34.8% of students reported they were not allowed to carry asthma medications in school. Specifically, nearly 51% of children ages 5 to 9 and 33% of children ages 10 to 14 were reported not to be allowed to carry medications at school. Further, 58.2% of children did not have a written asthma action plan. Reported urbanicity was not significantly associated with access to medication at school (p=0.46) or having an asthma action plan (p=0.57). Conclusions In our study, more than one-third of students were not permitted to carry asthma medications and nearly three-fifths did not have a written asthma action plan. Therefore, we recommend partnerships between schools, healthcare professionals, students, and osteopathic family physicians to increase access to asthma action plans and medication in schools.
    Type of Medium: Online Resource
    ISSN: 2702-3648
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2022
    detail.hit.zdb_id: 3045278-8
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    In: Journal of Osteopathic Medicine, Walter de Gruyter GmbH, Vol. 123, No. 3 ( 2023-02-22), p. 125-133
    Abstract: Adverse childhood experiences (ACEs) negatively impact health outcomes later in life, in a dose–dependent relationship; however, little is known about the impact of the individual ACE categories and subjective cognitive decline (SCD) later in life. Objectives The aim of this study was to determine the associations among the eight ACEs and SCD. Methods We analyzed data from two cycles of the Behavioral Risk Factor Surveillance System (BRFSS; 2019–2020). We assessed the accumulation of ACEs and their association with SCD, and among individuals reporting only one ACE, we utilized logistic regression to compare the likelihood of reporting SCD and symptomology among the eight categories of adversity. Results Among included respondents, 10.14% reported experiencing SCD. More ACEs were reported among those with SCD (mean, 2.61; SD, 2.56) compared to those without SCD (mean, 1.44; SD, 1.91). Those with higher ACE scores were significantly less likely to have spoken with a healthcare provider about their cognitive decline. Individuals reporting one ACE of either family mental illness, family substance abuse, family incarceration, emotional abuse, or physical abuse had significantly greater odds of reporting memory loss compared to individuals with no ACEs. Conclusions Having multiple ACEs was significantly associated with higher odds of SCD and associated limitation of social activity and was inversely associated with getting help when it is needed. Further, many ACE categories were associated with SCD – a novel addition to the literature and the methodology utilized herein. Interventions focused on improving cognitive health and preventing cognitive decline should consider the potential role of ACEs among affected populations.
    Type of Medium: Online Resource
    ISSN: 2702-3648
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2023
    detail.hit.zdb_id: 3045278-8
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    In: Nature Communications, Springer Science and Business Media LLC, Vol. 14, No. 1 ( 2023-09-23)
    Abstract: The ability of the pluripotent epiblast to contribute progeny to all three germ layers is thought to be lost after gastrulation. The later-forming neural crest (NC) rises from ectoderm and it remains poorly understood how its exceptionally high stem-cell potential to generate mesodermal- and endodermal-like derivatives is obtained. Here, we monitor transcriptional changes from gastrulation to neurulation using single-cell-Multiplex-Spatial-Transcriptomics (scMST) complemented with RNA-sequencing. We show maintenance of pluripotency-like signature ( Nanog , Oct4/PouV , Klf4 -positive) in undecided pan-ectodermal stem-cells spanning the entire ectoderm late during neurulation with ectodermal patterning completed only at the end of neurulation when the pluripotency-like signature becomes restricted to NC, challenging our understanding of gastrulation. Furthermore, broad ectodermal pluripotency-like signature is found at multiple axial levels unrelated to the NC lineage the cells later commit to, suggesting a general role in stemness enhancement and proposing a mechanism by which the NC acquires its ability to form derivatives beyond “ectodermal-capacity” in chick and mouse embryos.
    Type of Medium: Online Resource
    ISSN: 2041-1723
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2553671-0
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    Online Resource
    Online Resource
    American Geophysical Union (AGU) ; 1985
    In:  Journal of Geophysical Research: Space Physics Vol. 90, No. A7 ( 1985-07), p. 6475-6486
    In: Journal of Geophysical Research: Space Physics, American Geophysical Union (AGU), Vol. 90, No. A7 ( 1985-07), p. 6475-6486
    Abstract: A special selection of extremely quiet 1965 geomagnetic daily variation records from North America, Europe, central Asia, and east Asia was used to determine monthly spherical harmonic analysis coefficients representing the Sq fields from these regions. The coefficients permitted a separation of the external and internal contributions to the daily variations. Month‐by‐month behavior of the equivalent external current system and contours of the daily range of this current showed regional differences in amplitude and location of the equivalent ionospheric currents with seasonal change. Current foci locations reached 35° to 42° geomagnetic latitude in summer and 18° to 35° in winter with a regional dependence. The largest daily range of external current was 14.6×10 4 A in North America, 15.3×10 4 A in Europe, 13.7×10 4 A in central Asia, and 12.3×10 4 A in east Asia. Continental differences in the behavior of the current seemed to be explained by the relative position of the geographic and geomagnetic poles with respect to these regions.
    Type of Medium: Online Resource
    ISSN: 0148-0227
    Language: English
    Publisher: American Geophysical Union (AGU)
    Publication Date: 1985
    detail.hit.zdb_id: 2033040-6
    detail.hit.zdb_id: 3094104-0
    detail.hit.zdb_id: 2130824-X
    detail.hit.zdb_id: 2016813-5
    detail.hit.zdb_id: 2016810-X
    detail.hit.zdb_id: 2403298-0
    detail.hit.zdb_id: 2016800-7
    detail.hit.zdb_id: 161666-3
    detail.hit.zdb_id: 161667-5
    detail.hit.zdb_id: 2969341-X
    detail.hit.zdb_id: 161665-1
    detail.hit.zdb_id: 3094268-8
    detail.hit.zdb_id: 710256-2
    detail.hit.zdb_id: 2016804-4
    detail.hit.zdb_id: 3094181-7
    detail.hit.zdb_id: 3094219-6
    detail.hit.zdb_id: 3094167-2
    detail.hit.zdb_id: 2220777-6
    detail.hit.zdb_id: 3094197-0
    SSG: 16,13
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    Online Resource
    Online Resource
    American Geophysical Union (AGU) ; 1989
    In:  Eos, Transactions American Geophysical Union Vol. 70, No. 5 ( 1989-01-31), p. 66-74
    In: Eos, Transactions American Geophysical Union, American Geophysical Union (AGU), Vol. 70, No. 5 ( 1989-01-31), p. 66-74
    Abstract: The quiet daily variations of the geomagnetic field, called Sq, have been modeled for the extremely quiet (solar‐terrestrial disturbance) conditions using the digital values from magnetograms obtained from a worldwide distribution of observatories. This model, WDCA/SQ1, has been deposited at World Data Center A for Solar Terrestrial Physics as a set of data files and a Fortran computer program for retrieving the quiet variation field values at any world location, day of the year, and time of day. The WDCA/SQ1 model does not yet contain a solar‐cycle adjustment; it is a best representation for the sunspot minimum period. Presently, the dependence on year is just an adjustment for the geomagnetic coordinate system. Nevertheless, even in active years the model provides an adequate description of the minimum Sq changes.
    Type of Medium: Online Resource
    ISSN: 0096-3941 , 2324-9250
    Language: English
    Publisher: American Geophysical Union (AGU)
    Publication Date: 1989
    detail.hit.zdb_id: 24845-9
    detail.hit.zdb_id: 2118760-5
    detail.hit.zdb_id: 240154-X
    SSG: 16,13
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    Online Resource
    Online Resource
    Society of Geomagnetism and Earth, Planetary and Space Sciences ; 1992
    In:  Journal of geomagnetism and geoelectricity Vol. 44, No. 6 ( 1992), p. 459-480
    In: Journal of geomagnetism and geoelectricity, Society of Geomagnetism and Earth, Planetary and Space Sciences, Vol. 44, No. 6 ( 1992), p. 459-480
    Type of Medium: Online Resource
    ISSN: 0022-1392
    Language: English
    Publisher: Society of Geomagnetism and Earth, Planetary and Space Sciences
    Publication Date: 1992
    detail.hit.zdb_id: 2436627-4
    SSG: 16,13
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    Online Resource
    Online Resource
    American Thoracic Society ; 2004
    In:  American Journal of Respiratory and Critical Care Medicine Vol. 170, No. 3 ( 2004-08-01), p. 266-272
    In: American Journal of Respiratory and Critical Care Medicine, American Thoracic Society, Vol. 170, No. 3 ( 2004-08-01), p. 266-272
    Type of Medium: Online Resource
    ISSN: 1073-449X , 1535-4970
    RVK:
    Language: English
    Publisher: American Thoracic Society
    Publication Date: 2004
    detail.hit.zdb_id: 1468352-0
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. Further information can be found on the KOBV privacy pages