In:
FEBS Letters, Wiley, Vol. 271, No. 1-2 ( 1990-10), p. 19-22
Abstract:
Photoaffinity labelling with [α‐ 32 P]GTP allowed to detect a 54 kDa GTP‐binding protein in rat pancreatic plasma membranes and in pancreatic AR 4‐2J cell membranes. Like the 42 and 48 kDa G s α subunits and the 41 kDa G i α subunit, this protein was absent from zymogen granule membranes. Contrastingly, a new 28 kDa GTP‐binding protein (detected by [α‐ 32 P]GTP binding on immobilized proteins) and a 25 kDa protein (ADP‐ribosylated by botulinum toxin D) were found in all three membrane preparations. This is to our knowledge the first report on GTP‐binding proteins in zymogen granule membranes.
Type of Medium:
Online Resource
ISSN:
0014-5793
,
1873-3468
DOI:
10.1016/0014-5793(90)80362-M
Language:
English
Publisher:
Wiley
Publication Date:
1990
detail.hit.zdb_id:
1460391-3
SSG:
12
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