In:
Psychotherapy and Psychosomatics, S. Karger AG, Vol. 91, No. 1 ( 2022), p. 36-49
Abstract:
〈 b 〉 〈 i 〉 Introduction: 〈 /i 〉 〈 /b 〉 The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) delivered in a group format could facilitate the implementation of evidence-based psychological treatments. 〈 b 〉 〈 i 〉 Objective: 〈 /i 〉 〈 /b 〉 This study compared the efficacy of group UP and diagnosis-specific cognitive behavioral therapy (dCBT) for anxiety and depression in outpatient mental health services. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 In this pragmatic, multi-center, single-blinded, non-inferiority, randomized controlled trial (RCT), we assigned 291 patients with major depressive disorder, social anxiety disorder, panic disorder, or agoraphobia to 14 weekly sessions in mixed-diagnosis UP or single-diagnosis dCBT groups. The primary test was non-inferiority, using a priori criteria, on the World Health Organisation 5 Well-Being Index (WHO-5) at the end of the treatment. Secondary outcomes were functioning and symptoms. We assessed outcomes at baseline, end-of-treatment, and at a 6-month follow-up. A modified per-protocol analysis was performed. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 At end-of-treatment, WHO-5 mean scores for patients in UP ( 〈 i 〉 n 〈 /i 〉 = 148) were non-inferior to those of patients in dCBT ( 〈 i 〉 n 〈 /i 〉 = 143; mean difference –2.94; 95% CI –8.10 to 2.21). Results were inconclusive for the WHO-5 at the 6-month follow-up. Results for secondary outcomes were non-inferior at end-of-treatment and the 6-month follow-up. Client satisfaction and rates of attrition, response, remission, and deterioration were similar across conditions. 〈 b 〉 〈 i 〉 Conclusions: 〈 /i 〉 〈 /b 〉 This RCT demonstrated non-inferior acute-phase outcomes of group-delivered UP compared with dCBT for major depressive disorder, social anxiety disorder, panic disorder, and agoraphobia in outpatient mental health services. The long-term effects of UP on well-being need further investigation. If study findings are replicated, UP should be considered a viable alternative to dCBT for common anxiety disorders and depression in outpatient mental health services.
Type of Medium:
Online Resource
ISSN:
0033-3190
,
1423-0348
Language:
English
Publisher:
S. Karger AG
Publication Date:
2022
detail.hit.zdb_id:
1472321-9
SSG:
5,2
SSG:
15,3
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