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  • 1
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2021
    In:  Female Pelvic Medicine & Reconstructive Surgery Vol. 27, No. 1 ( 2021-1), p. e184-e186
    In: Female Pelvic Medicine & Reconstructive Surgery, Ovid Technologies (Wolters Kluwer Health), Vol. 27, No. 1 ( 2021-1), p. e184-e186
    Abstract: The aim of the study was to compare levator hiatus (LH) and levator area (LA) on transvaginal 3-dimensional (3D) ultrasound (US) and genital hiatus (GH) size by Pelvic Organ Prolapse Quantification (POP-Q) examination before and after minimally invasive sacrocolpopexy. Methods Women with prolapse (POP) beyond the hymen undergoing minimally invasive sacrocolpopexy without concomitant POP repairs completed Pelvic Floor Distress Inventory short form (PFDI), POP-Q, and transvaginal 3D US before and 14 weeks after surgery. Data were analyzed by 2 urogynecologists, blinded to US image sequence and to corresponding POP-Q scores. Results Forty-three patients were enrolled; 35 with complete data are included. Patients had a mean ± SD age of 55 ± 11 years. Most were white (89%), vaginally parous (94%), postmenopausal (66%), sexually active (63%), and had stage 3 POP (86%). The majority (89%) had concomitant hysterectomy, and 60% had midurethral slings. At baseline, the mean ± SD PFDI and Prolapse subscale of the Pelvic Floor Distress Inventory scores were 98 ± 50 and 42 ± 22. The median (interquartile range) POP-Q stage decreased after surgery from 3 (3) to 0 (0–1, P 〈 0.001) and the mean ± SD PFDI scores decreased to 55 ± 42 ( P = 0.002). At baseline, the mean ± SD GH and perineal body measurements were 3.5 ± 0.7 and 2.4 ± 0.6 cm. Although the GH size decreased by 0.5 cm after surgery, perineal body was unchanged. Levator hiatus remained unchanged between the baseline and 14-week visits ( P = 0.07), whereas LA increased by 0.8 cm 2 ( P = 0.03). At 14 weeks, the change in LA was not correlated with the change in GH ( ρ = −0.2, P = 0.2) or POP stage ( ρ = −0.2, P = 0.9). Conclusions Restoring the apex with sacrocolpopexy alone reduces GH size on clinical examination; however, it does not impact the size of the underlying LH on US.
    Type of Medium: Online Resource
    ISSN: 2151-8378
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2021
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  • 2
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2021
    In:  Female Pelvic Medicine & Reconstructive Surgery Vol. 27, No. 1 ( 2021-1), p. e118-e121
    In: Female Pelvic Medicine & Reconstructive Surgery, Ovid Technologies (Wolters Kluwer Health), Vol. 27, No. 1 ( 2021-1), p. e118-e121
    Abstract: The aim of the study was to describe the rate of symptomatic and asymptomatic urinary retention and catheterization in women undergoing initial intravesical onabotulinumtoxinA (BnTA) injection for urgency urinary incontinence (UUI). Methods This retrospective chart review included women receiving initial 100 U of BnTA injection for UUI for 5 years. Straight-catheterized postvoid residuals (PVRs) were performed 2 weeks after the injection. Women without the sensation of incomplete bladder emptying, worsened urgency, inability to void, or suprapubic pain but with PVR of greater than 300 mL were characterized as having asymptomatic retention , whereas women with a PVR of greater than 150 and any of these symptoms were diagnosed with symptomatic retention . Results One hundred eighty-seven 187 patients received initial BnTA injection. The majority were postmenopausal (89%) and white (82%) with a mean age of 65 years and body mass index of 30 kg/m 2 . One-third of the cohort underwent baseline urodynamic studies. At 2 weeks after injection, 163 patients (87%) followed up, and 17 (10%) had either asymptomatic or symptomatic retention (2% and 8%, respectively). There were no differences in demographic or pretreatment urodynamic parameters in women with and without retention except that women who had previous anti–stress urinary incontinence procedures were more likely to experience retention (53% vs 18%, P = 0.002) despite similar baseline PVRs. Conclusion We demonstrated that the rate of retention requiring catheterization after 100 U BnTA may be as high as 10% although only 5% develop PVRs for 300 mL and only 2% have asymptomatic retention for 300 mL.
    Type of Medium: Online Resource
    ISSN: 2151-8378
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2021
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  • 3
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2021
    In:  Female Pelvic Medicine & Reconstructive Surgery Vol. 27, No. 2 ( 2021-2), p. e333-e335
    In: Female Pelvic Medicine & Reconstructive Surgery, Ovid Technologies (Wolters Kluwer Health), Vol. 27, No. 2 ( 2021-2), p. e333-e335
    Abstract: To describe surgical technique and outcomes of early secondary repair of obstetric anal sphincter injury (OASIS) breakdown. Methods This was a case series of all women presenting to a subspecialty peripartum clinic within 2 months of an OASIS, who ultimately underwent secondary surgical repair between September 2013 and January 2018. Cases were identified using the following CPT codes: 57308 (transperineal fistula repair), 56910 (repair of the perineum), and 46750 (repair of anal sphincter). Four board-certified urogynecologists performed all surgical procedures using the same technique: demographics, delivery data, and preoperative and postoperative data were collected. Results Eighteen women were identified. The majority (16 [88.9%] of 18) were primiparous; 9 (50%) women underwent spontaneous vaginal delivery and 9 (50%) women underwent forceps-assisted vaginal delivery. Over 70% (13 [72.2%] of 18) suffered a 3rd-degree tear, whereas 5 (27.8%) of 18 had a 4th-degree laceration. The median time after delivery to specialty clinic presentation was 10 days (interquartile range, 5.3–52.5 days). All women were diagnosed with wound breakdown at their initial visit. Seven (38.9%) also had a concomitant rectovaginal fistula. Median time from diagnosis of wound breakdown to secondary operative revision was 19.5 days (interquartile range, 12–26.8 days). Seventeen (94.4%) of the 18 women underwent overlapping external anal sphincteroplasty with perineorrhaphy; of these, 7 (41.2%) also underwent concurrent repair of their rectovaginal fistula. One woman underwent perineorrhaphy alone. At 3 months postoperatively, no women had a wound breakdown or recurrent fistula. Conclusions In women with OASIS breakdown, early secondary repair is both feasible and successful with meticulous surgical technique.
    Type of Medium: Online Resource
    ISSN: 2151-8378
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2021
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  • 4
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2022
    In:  Aesthetic Plastic Surgery Vol. 46, No. 4 ( 2022-08), p. 1724-1730
    In: Aesthetic Plastic Surgery, Springer Science and Business Media LLC, Vol. 46, No. 4 ( 2022-08), p. 1724-1730
    Type of Medium: Online Resource
    ISSN: 0364-216X , 1432-5241
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 1462126-5
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  • 5
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2020
    In:  Obstetrics & Gynecology Vol. 135, No. 1 ( 2020-05), p. 130S-130S
    In: Obstetrics & Gynecology, Ovid Technologies (Wolters Kluwer Health), Vol. 135, No. 1 ( 2020-05), p. 130S-130S
    Abstract: We aimed to evaluate the relationship between predicted success of trial of labor after cesarean (TOLAC) and obstetric anal sphincter injury (OASI) to develop a predictive model. METHODS: We performed a secondary analysis of the Maternal Fetal Medicine Units Network (MFMU) TOLAC prospective cohort (1999–2002) and a single-site retrospective analysis of a cohort of women with a singleton vaginal birth after cesarean (VBAC) between 2011 and 2016 (modern population [MP]) (IRB approval STU00204149). Women were stratified by the presence of OASI and characteristics were compared wit h bivariate analysis, including the predicted probability of achieving VBAC using the MFMU calculator. Significant risk factors were included in a backward stepwise multivariable logistic regression model to identify independent risk factors for OASI and generate a predictive model. Model performance was evaluated using concordance indices, brier scores and calibration plots. Internal validity was assessed with bootstrapping and external validation performed using MP data. RESULTS: 12,108 women met inclusion criteria and 739 (6.1%) sustained OASI. Factors independently associated with OASI included forceps (OR 5.0 CI 4.1-6.2) and vacuum (OR 2.8 CI 2.2-3.6), along with predicted likelihood of VBAC (aOR 0.5 CI 0.4-0.6), race and smoking. The concordance index of the model and MP validation cohort was 0.79 (CI 0.77-0.81) and 0.77 (CI 0.71-0.83). The model demonstrates internal validity, but slight overcalibration within the MP cohort. CONCLUSION: Predicted likelihood of VBAC is inversely proportional to the likelihood of sustaining OASI. Our model provides a robust estimate of OASI risk during VBAC that can be easily utilized in counseling.
    Type of Medium: Online Resource
    ISSN: 0029-7844
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2020
    detail.hit.zdb_id: 2012791-1
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  • 6
    In: American Journal of Perinatology, Georg Thieme Verlag KG, Vol. 39, No. 07 ( 2022-05), p. 750-758
    Abstract: Objective This study aimed to estimate whether there is an association between the predicted probability of vaginal birth after cesarean delivery (VBAC) and the occurrence of obstetric anal sphincter injuries (OASIS). Study Design This was a single-site retrospective cohort study of all women with a singleton vaginal birth after a previous cesarean section between January 2011 and December 2016. Women were divided into four ordinal groupings by the predicted probability of achieving vaginal birth after cesarean using the Maternal–Fetal Medicine Units Network VBAC calculator (less than 41%, 40.1–60%, 60.1–80%, and greater than 80%). The primary outcome was OASIS, defined as a 3rd or 4th degree perineal laceration. Bivariable and multivariable analyses were used to examine the association between predicted VBAC probability and OASIS. Results In total, 1,411 women met inclusion criteria and 73 (5.2%) sustained OASIS. The median predicted probability of VBAC was lower in women with OASIS compared with those without OASIS (60% [interquartile range {IQR}: 48–70%] vs. 66% (IQR: 52–80%), p = 0.02] . On bivariable and multivariable logistic regression, predicted probability of VBAC was associated with increased odds of OASIS (less than 41% probability: adjusted odds ratio [aOR]: 3.18, 95% confidence interval [CI] : 0.90–11.21; 41–60% probability: aOR: 3.76, 95% CI: 1.34–10.57; 61–80% probability aOR: 3.47, 95% CI: 1.25–9.69) relative to women with a predicted probability of VBAC of greater than 80%. Conclusion Having a lower predicted probability of VBAC is associated with an increased risk of OASIS at the time of a VBAC relative to those with greater than 80% predicted probability. Incorporation of this aspect of maternal morbidity may inform risk-stratification at the time of trial of labor after cesarean, as well as the choice of performing an operative vaginal delivery. Key Points
    Type of Medium: Online Resource
    ISSN: 0735-1631 , 1098-8785
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2022
    detail.hit.zdb_id: 2042426-7
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  • 7
    Online Resource
    Online Resource
    Elsevier BV ; 2021
    In:  American Journal of Obstetrics and Gynecology Vol. 225, No. 2 ( 2021-08), p. 173.e1-173.e8
    In: American Journal of Obstetrics and Gynecology, Elsevier BV, Vol. 225, No. 2 ( 2021-08), p. 173.e1-173.e8
    Type of Medium: Online Resource
    ISSN: 0002-9378
    RVK:
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2021
    detail.hit.zdb_id: 2003357-6
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