UID:
edoccha_9958056777802883
Umfang:
1 online resource (420 p.)
ISBN:
1-280-62851-0
,
9786610628513
,
0-08-045934-X
Inhalt:
Systems Biology is concerned with the quantitative study of complex biosystems at the molecular, cellular, tissue, and systems scales. Its focus is on the function of the system as a whole, rather than on individual parts. This exciting new arena applies mathematical modeling and engineering methods to the study of biological systems. This book is the first of its kind to focus on the newly emerging field of systems biology with an emphasis on computational approaches. The work covers new concepts, methods for information storage, mining and knowledge extraction, reverse engineering of
Anmerkung:
Description based upon print version of record.
,
Front cover; Title page; Copyright page; Table of contents; Preface; 1. Introducing Computational Systems Biology; 2. Databases for Systems Biology; 3. Natural Language Processing and Ontology-enhanced Biomedical Literature Mining for Systems Biology; 4. Integrated Imaging Informatics; 5. Simpathica: A Computational Systems Biology Tool within the Valis Bioinformatics Environment; 6. Standards, Platforms, and Applications; 7. Introduction to Computational Models of Biochemical Reaction Networks; 8. Biological Foundations of Signal Transduction and the Systems Biology Perspective
,
9. Reconstruction of Metabolic Network from Genome Information and Its Structural and Functional Analysis10. Integrated Regulatory and Metabolic Models; 11. Gene Networks: Estimation, Modeling, and Simulation; 12. A Discrete Approach to Top-Down Modeling of Biochemical Networks; 13. Computational Models for Circadian Rhythms: Deterministic Versus Stochastic Approaches; 14. Multistability and Multicellularity: Cell Fates as High-dimensional Attractors of Gene Regulatory Networks; 15. Spatio-Temporal Systems Biology; 16. Cytomics-from Cell States to Predictive Medicine
,
17. The IUPS Physiome Project: Progress and PlansIndex
,
English
Weitere Ausg.:
ISBN 0-12-088786-X
Sprache:
Englisch
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