In:
Tumori Journal, SAGE Publications, Vol. 72, No. 2 ( 1986-04), p. 139-143
Abstract:
We studied urinary excretion levels of neopterin in 30 cancer patients affected by non-Hodgkin's lymphomas, Hodgkin's disease and multiple myeloma compared to 30 healthy subjects. Mean value of neopterin excretion in cancer patients (576.01 ± 620.37) appeared significantly increased (p 〈 0.001) compared to normal controls (134.40 ± 41.65). A neopterin excretion above the upper normal limit was observed in 23/28 (82%) patients with active disease. A trend to an increased urinary level of neopterin with more advanced stage was observed, namely in patients with bone marrow involvement and constitutional symptoms. We suggest that the evaluation of urinary neopterin levels may be of value in the diagnosis and follow-pu of hematologic malignancies.
Type of Medium:
Online Resource
ISSN:
0300-8916
,
2038-2529
DOI:
10.1177/030089168607200204
Language:
English
Publisher:
SAGE Publications
Publication Date:
1986
detail.hit.zdb_id:
280962-X
detail.hit.zdb_id:
2267832-3
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