In:
Brazilian Journal of Development, South Florida Publishing LLC, Vol. 8, No. 11 ( 2022-11-22), p. 74187-74195
Kurzfassung:
Psidium guajava is popularly known as guava. It is a very common species in South America, found most often in tropical climate. It is a plant known for its anti-inflammatory property, used in folk medicine for combating intestinal discomfort, colic, colitis, among others. The leaves of P. guajava present flavonoids in their composition, with emphasis on quercetin. The flavonoid class has antioxidant properties and acts on the central nervous system through oxidative inhibition of the endoplasmic reticulum. Thus, the objective of this study was to quantify the quercetin of the aerial parts of guava. Therefore, ethanol extraction was performed, followed by fractionation with solvents of different polarities, obtaining the hexanic, dichloromethane and ethyl acetate fractions. Then, quercetin was identified in the ethyl acetate fraction by Thin Layer Chromatography (CCD), the total flavonoid content was quantified by spectrophotometry and quercetin by High Efficiency Liquid Chromatography (HPLC). The qualitative analysis in CCD of the ethyl acetate fraction revealed the presence of flavonoids. Quantitative spectrophotometry analysis showed 46.2 mg of total flavonoids per g of the ethyl acetate fraction, being 816 μg g-1 of quercetin revealed by HPLC. With this study, it was possible to identify the presence of flavonoids, and about 2% correspond to the substance quercetin, present in the ethyl acetate fraction of P. guajava. Therefore, further studies can be carried out aiming at the isolation of quercetin for application in a pharmaceutical form acting on the central nervous system.
Materialart:
Online-Ressource
ISSN:
2525-8761
DOI:
10.34117/bjdv8n11-229
Sprache:
Unbekannt
Verlag:
South Florida Publishing LLC
Publikationsdatum:
2022
ZDB Id:
2873644-8
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