Format:
1 online resource (367 pages)
ISBN:
9784431546283
Content:
Intro -- Preface -- Contents -- Part I: From Molecular Mechanism to Intervention for Congenital Heart Diseases, Now and the Future -- Perspective -- 1: Reprogramming Approaches to Cardiovascular Disease: From Developmental Biology to Regenerative Medicine -- 1.1 Introduction -- 1.2 Molecular Networks Regulate Cardiac Cell Fate -- 1.3 Cardiac Fibroblasts in the Normal and Remodeling Heart -- 1.4 Direct Cardiac Reprogramming In Vitro -- 1.5 Direct Cardiac Reprogramming In Vivo -- 1.6 Direct Cardiac Reprogramming in Human Fibroblasts -- 1.7 Challenges and Future Directions -- References -- 2: The Arterial Epicardium: A Developmental Approach to Cardiac Disease and Repair -- 2.1 Origin of the Epicardium -- 2.2 Epicardium-Derived Cells (EPDCs) -- 2.3 Heterogeneity of Epicardial Cells -- 2.3.1 The Cardiac Fibroblast -- 2.3.2 Arterial Smooth Muscle Cell -- 2.3.3 Endothelial Cells -- 2.3.4 Cardiomyocytes -- 2.3.5 The Purkinje Fiber -- 2.4 Congenital and Adult Cardiac Disease -- 2.4.1 Non-compaction -- 2.4.2 Conduction System Anomalies -- 2.4.3 Valvulopathies -- 2.4.4 Coronary Vascular Anomalies -- 2.5 Cardiovascular Repair -- 2.6 Future Directions and Clinical Applications -- References -- 3: Cell Sheet Tissue Engineering for Heart Failure -- 3.1 Introduction -- 3.2 Cell Sheet Engineering -- 3.3 Cardiac Tissue Reconstruction -- 3.4 Cell Sheet Transplantation in Small Animal Models -- 3.5 Cell Sheet Transplantation in Preclinical and Clinical Studies -- 3.6 Conclusions -- References -- 4: Future Treatment of Heart Failure Using Human iPSC-Derived Cardiomyocytes -- 4.1 Introduction -- 4.2 Cardiac Differentiation from Human iPSCs -- 4.3 Nongenetic Methods for Purifying Cardiomyocytes -- 4.4 Transplantation of Human PSC-Derived Cardiomyocytes -- 4.5 Future Directions -- References -- 5: Congenital Heart Disease: In Search of Remedial Etiologies.
Note:
Description based on publisher supplied metadata and other sources
Additional Edition:
ISBN 9784431546276
Additional Edition:
Erscheint auch als Druck-Ausgabe ISBN 9784431546276
Language:
English
Bookmarklink