In:
European Journal of Organic Chemistry, Wiley, Vol. 26, No. 35 ( 2023-09-14)
Abstract:
Due to the high oxidation potentials of electron‐deficient aromatic hydrocarbons, it is difficult to achieve the direct oxidative C(sp 2 )−H bonds functionalizations of such substrates. Herein, we develop a Ritter‐type amination of electron‐deficient aromatics by merging electricity and sulfate. This practical and straightforward method provides a series of acetanilides from simple electron‐deficient arenes, including mono‐, di‐ and tri‐substituted arenes (22 examples, up to 75 %) with moderate to good yields under mild conditions. This method is characterized by cheap and readily available regents, atom and step economy.
Type of Medium:
Online Resource
ISSN:
1434-193X
,
1099-0690
DOI:
10.1002/ejoc.202300553
Language:
English
Publisher:
Wiley
Publication Date:
2023
detail.hit.zdb_id:
1475010-7
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