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  • S. Karger AG  (14)
  • 2015-2019  (14)
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  • S. Karger AG  (14)
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  • 2015-2019  (14)
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  • 1
    Online Resource
    Online Resource
    Leitlinienarbeit im Bereich Naturheilkunde und Komplementärmedizin - das Potenzial ist noch lange nicht erschöpft
    S. Karger AG ; 2016
    In:  Forschende Komplementärmedizin / Research in Complementary Medicine Vol. 23, No. 3 ( 2016), p. 145-146
    Details
    In: Forschende Komplementärmedizin / Research in Complementary Medicine, S. Karger AG, Vol. 23, No. 3 ( 2016), p. 145-146
    Type of Medium: Online Resource
    ISSN: 1661-4119 , 1661-4127
    URL: Article
    DOI: 10.1159/000447314
    RVK:
    XA 10000
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2016
    detail.hit.zdb_id: 2888724-4
    detail.hit.zdb_id: 1468807-4
    SSG: 15,3
    SSG: 5,21
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  • 2
    Online Resource
    Online Resource
    Efficacy of Caraway Oil Poultices in Treating Irritable Bowel Syndrome - A Randomized Controlled Cross-Over Trial
    S. Karger AG ; 2015
    In:  Digestion Vol. 92, No. 1 ( 2015), p. 22-31
    Details
    In: Digestion, S. Karger AG, Vol. 92, No. 1 ( 2015), p. 22-31
    Abstract: 〈 b 〉 〈 i 〉 Background/Aim: 〈 /i 〉 〈 /b 〉 Irritable bowel syndrome (IBS) is a frequent gastrointestinal disorder, with only limited evidence regarding self-management approaches. This study tested the efficacy of caraway oil poultices (CarO) for treating IBS. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 This randomized controlled open-label cross-over trial included three treatment periods with hot CarO and hot olive oil poultice (OlivH) or nonheated poultices (OlivC) with olive oil as control interventions. Patients applied each intervention daily for 3 weeks. The primary outcome was symptom severity (IBS-SSS); secondary outcomes included responder rates (improvement ≥50 IBS-SSS), quality of life (EQ-5D, IBS-QOL), psychological distress (HADS), adequate relief, and safety. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 48 patients with IBS were included (40 females, 53.9 ± 14.4 years). A significant difference was found for symptom severity in favor of CarO compared to OlivC (difference -38.4, 95% CI -73.6, -3.1, p = 0.033), but not compared to OlivH (difference -24.3, 95% CI -56.5, 7.9, p = 0.139). Responder rates were highest for CarO compared to OlivH and OlivC (43.9, 20.0, 18.9%, respectively). Within the CarO, 51.8% reported adequate relief compared to 23.5% (OlivH) and 25.8% (OlivC). One adverse event (gastrointestinal infection) was reported during CarO. 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 Hot caraway oil poultices appear effective and safe, although their effects may be a result of the heat application. Patients reported highest levels of subjective benefit from caraway oil poultices, making their use appropriate in the self-management of IBS.
    Type of Medium: Online Resource
    ISSN: 0012-2823 , 1421-9867
    URL: Article
    DOI: 10.1159/000398790
    RVK:
    XA 40650
    RVK:
    XA 10000
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2015
    detail.hit.zdb_id: 1482218-0
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  • 3
    Online Resource
    Online Resource
    The Predictive Value of the Hydrogen Breath Test in the Diagnosis of Fructose Malabsorption
    S. Karger AG ; 2019
    In:  Digestion Vol. 99, No. 2 ( 2019), p. 140-147
    Details
    In: Digestion, S. Karger AG, Vol. 99, No. 2 ( 2019), p. 140-147
    Abstract: 〈 b 〉 〈 i 〉 Background: 〈 /i 〉 〈 /b 〉 Fructose malabsorption is commonly diagnosed by the hydrogen fructose (H 〈 sub 〉 2 〈 /sub 〉 ) breath test. However, the mechanisms behind fructose malabsorption in humans are not well understood and the clinical relevance of this test is considered controversial. Hence, the main aim of this study is to evaluate the predictive value of the H 〈 sub 〉 2 〈 /sub 〉 breath test. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 Regarding exclusion criteria, the study enrolled 562 consecutive patients, enlisted to a gastroenterology clinic between 2009 and 2011 for testing malabsorption. In the final data analysis, 246 patients were included. Ecotrophologists used 3 categories to rate dietary success: complete response, partial response and no response to the diet. They also rated the occurrence of abdominal pain, diarrhoea and bloating during the H 〈 sub 〉 2 〈 /sub 〉 breath test. Ordinal regression analysis using SPSS was performed to evaluate whether H 〈 sub 〉 2 〈 /sub 〉 breath test results – measured as the maximum H 〈 sub 〉 2 〈 /sub 〉 level, the maximum increase in H 〈 sub 〉 2 〈 /sub 〉 , and the area under the curve (AUC) – predicted dietary success or failure. Correlation analyses were applied to test whether symptoms of fructose malabsorption correlated with the H 〈 sub 〉 2 〈 /sub 〉 breath test measures. Finally, we evaluated whether cut-off-values of 40 or 60 parts per million (ppm) serve better than the test measure of 20 ppm to diagnose fructose malabsorption. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 When a fructose-free diet was administered it was found that 103 patients (41.9%) were complete responders, 116 (47.2%) were partial responders and 27 (11%) were non-responders. The H 〈 sub 〉 2 〈 /sub 〉 breath test with the 20 ppm cut-off-value, that is, the maximum H 〈 sub 〉 2 〈 /sub 〉 level, the maximum increase in H 〈 sub 〉 2 〈 /sub 〉 , and the AUC did not predict dietary response (all 95% CI ns). This was also the case when using 40 or 60 ppm as cut-off-values (all 95% CI ns). Abdominal pain during the test correlated significantly with the AUC. Diarrhoea and bloating correlated significantly with the AUC, the maximum H 〈 sub 〉 2 〈 /sub 〉 level and the maximum increase in H 〈 sub 〉 2 〈 /sub 〉 ( 〈 i 〉 p 〈 /i 〉 & #x3c; 0.05). 〈 b 〉 〈 i 〉 Conclusions: 〈 /i 〉 〈 /b 〉 The H 〈 sub 〉 2 〈 /sub 〉 breath test produced no predictive value for the fructose-free diet outcomes; its value as a predictive test is therefore questionable. However, the symptoms of fructose malabsorption correlated significantly with the H 〈 sub 〉 2 〈 /sub 〉 breath test measures, and this is an indication that there is at least a degree of validity of the H2 breath test beyond the simple detection or exclusion of fructose malabsorption.
    Type of Medium: Online Resource
    ISSN: 0012-2823 , 1421-9867
    URL: Article
    DOI: 10.1159/000489877
    RVK:
    XA 40650
    RVK:
    XA 10000
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2019
    detail.hit.zdb_id: 1482218-0
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  • 4
    Online Resource
    Online Resource
    Herbal Medicine for Cough: a Systematic Review and Meta-Analysis
    S. Karger AG ; 2015
    In:  Complementary Medicine Research Vol. 22, No. 6 ( 2015), p. 359-368
    Details
    In: Complementary Medicine Research, S. Karger AG, Vol. 22, No. 6 ( 2015), p. 359-368
    Abstract: 〈 b 〉 〈 i 〉 Background: 〈 /i 〉 〈 /b 〉 The aim of this review was to systematically assess the literature on herbal medicine for cough as a symptom of upper respiratory tract infections and common cold. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 The Cochrane Library, Scopus, MEDLINE/PubMed, and Embase were searched through March 2012 for RCTs testing the effects of herbal medicine for cough. Risk of bias was assessed using the Cochrane tool. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 34 RCTs (N = 7,083) on 〈 i 〉 Pelargonium sidoides 〈 /i 〉 (11 RCTs), 〈 i 〉 Echinacea 〈 /i 〉 (8 RCTs), 〈 i 〉 Andrographis paniculata 〈 /i 〉 (6 RCTs), ivy/primrose/thyme (4 RCTs), essential oils (4 RCTs) and bakumondoto (1 RCT) were included. Controls were mainly placebo. Most studies had a low risk of bias. The meta-analysis revealed strong evidence for 〈 i 〉 A. paniculata 〈 /i 〉 (SMD = -1.00, 95% CI = -1.85, -0.15; P 〈 0.001) and ivy/primrose/thyme (RR = 1.40, 95% CI = 1.23, 1.60; P 〈 0.001) in treating cough; moderate evidence for 〈 i 〉 P. sidiodes 〈 /i 〉 (RR = 4.60; 95% CI = 2.89,7.31; P 〈 0.001), and limited evidence for 〈 i 〉 Echinacea 〈 /i 〉 (SMD = -0.68; 95% CI = -1.32, -0.04; P = 0.04). 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 This review found strong evidence for 〈 i 〉 A. paniculata 〈 /i 〉 and ivy/primrose/thyme-based preparations and moderate evidence for 〈 i 〉 P. sidoides 〈 /i 〉 being significantly superior to placebo in alleviating the frequency and severity of patients' cough symptoms. Additional research, including other herbal treatments, is needed in this area.
    Type of Medium: Online Resource
    ISSN: 2504-2092 , 2504-2106
    URL: Article
    DOI: 10.1159/000442111
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2015
    detail.hit.zdb_id: 2888724-4
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  • 5
    Online Resource
    Online Resource
    A Systematic Review of Phytotherapy for Acute Rhinosinusitis
    S. Karger AG ; 2016
    In:  Complementary Medicine Research Vol. 23, No. 3 ( 2016), p. 165-169
    Details
    In: Complementary Medicine Research, S. Karger AG, Vol. 23, No. 3 ( 2016), p. 165-169
    Abstract: Herbal medicine is a promising alternative in the treatment of acute rhinosinusitis (ARS). We performed a systematic review for phytopharmaceutical treatments of ARS. A computerized search of databases (Cochrane Library, PubMed, and Scopus) up to 16 September 2015 was performed. Randomized controlled trials (RCTs) and controlled trials (CTs) were included and assessed using the Cochrane risk of bias tool. Seven trials on 〈 i 〉 Pelargonium sidoides 〈 /i 〉 (EPs 7630, Umckaloabo®), Myrtol (GeloMyrtol® forte), BNO 1016 (Sinupret® extract), BNO 101 (Sinupret®), 〈 i 〉 Cyclamen europaeum 〈 /i 〉 (Nasodren®), and Esberitox® were included. Risk of bias was heterogeneous. EPs 7630 appeared to be useful in the treatment of ARS. Myrtol showed benefits against a placebo compound, and BNO 1016 and BNO 101 might be helpful; however, there was little evidence for the effectiveness of 〈 i 〉 Cyclamen europaeum 〈 /i 〉 and Esberitox®. Herbal medicine might be effective for the treatment of ARS, but given the low number of clinical trials and the heterogeneous methodological quality, further research is necessary.
    Type of Medium: Online Resource
    ISSN: 2504-2092 , 2504-2106
    URL: Article
    DOI: 10.1159/000447467
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2016
    detail.hit.zdb_id: 2888724-4
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  • 6
    Online Resource
    Online Resource
    Berücksichtigung von Wechsel- und Nebenwirkungen bei pflanzlichen Arzneimitteln in deutschen S3-Leitlinien der AWMF
    S. Karger AG ; 2016
    In:  Complementary Medicine Research Vol. 23, No. 3 ( 2016), p. 154-164
    Details
    In: Complementary Medicine Research, S. Karger AG, Vol. 23, No. 3 ( 2016), p. 154-164
    Abstract: Pflanzliche Arzneimittel haben in der medizinischen Versorgung im deutschsprachigen Raum eine lange Tradition, werden aber bei der Erstellung medizinischer Leitlinien selten berücksichtigt. In einer Vorstudie wurde von unserer Arbeitsgruppe aufgearbeitet, in welchem Ausmaß sie in den aktuellen interdisziplinär, evidenz- und konsensusbasiert erstellten S3-Leitlinien der Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF) Beachtung gefunden haben. Ziel der jetzigen Studie war es, zu analysieren, inwieweit Neben- bzw. Wechselwirkungen von pflanzlichen Arzneimitteln in diesen S3-Leitlinien diskutiert werden. Im Januar 2015 wurden 134 S3-Leitlinien gezählt und analysiert. 27,6% (n = 37) weisen insgesamt 194 Statements unter dem Begriff «Phytotherapie» auf. Hinweise zu Neben- und Wechselwirkungen finden sich in 28,4% der Statements (n = 55), die bei 13,9% (n = 27) durch Literatur belegt werden. 14 dieser Statements betreffen Nahrungsergänzungsmittel und Ähnliches, 11 sind pauschale Aussagen zur Phytotherapie, 7 fassen mindestens 2 Arzneipflanzen pauschal zusammen. Damit weisen nur 23 Statements auf Neben- bzw. Wechselwirkungen von einzelnen Arzneipflanzen hin, 14 davon sind mit Literaturstellen belegt. Diese Ergebnisse entsprechen bei Weitem nicht den geforderten Standards der AWMF. Dafür verantwortlich sind insbesondere unpräzise Begrifflichkeiten sowie eine unzureichende Systematik bei der Suche nach wissenschaftlicher Evidenz für die Unbedenklichkeit von Arzneipflanzen-Zubereitungen. Die Gesellschaft für Phytotherapie kann hier einen wichtigen Beitrag zur Qualitätsverbesserung leisten.
    Type of Medium: Online Resource
    ISSN: 2504-2092 , 2504-2106
    URL: Article
    DOI: 10.1159/000446573
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2016
    detail.hit.zdb_id: 2888724-4
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  • 7
    Online Resource
    Online Resource
    Erfolgreiche therapeutische endoskopisch-endoluminale Procaininstillation in eine Anastomosenregion bei chronischem Symptomkomplex nach operativer Versorgung einer angeborenen Ösophagusatresie
    S. Karger AG ; 2019
    In:  Complementary Medicine Research Vol. 26, No. 3 ( 2019), p. 206-209
    Details
    In: Complementary Medicine Research, S. Karger AG, Vol. 26, No. 3 ( 2019), p. 206-209
    Abstract: 〈 b 〉 〈 i 〉 Hintergrund: 〈 /i 〉 〈 /b 〉 Wir berichten über eine 27-jährige Patientin, die nach operativem Magenhochzug bei Ösophagusatresie unter massiv einschränkenden Symptomen wie Sodbrennen, Erbrechen, Regurgitation, Übelkeit und Magenkrämpfen litt, trotz maximaler konservativer Therapie. 〈 b 〉 〈 i 〉 Falldarstellung: 〈 /i 〉 〈 /b 〉 Die Patientin erhielt im Rahmen einer Gastroskopie eine endoluminale Procaininfiltration in die narbige Anastomosenregion, woraufhin sich die klinische Symptomatik deutlich reduzierte und auch im Langzeitverlauf stabil vermindert blieb. 〈 b 〉 〈 i 〉 Schlussfolgerung: 〈 /i 〉 〈 /b 〉 Wir beschreiben die unseres Wissens nach erste endoluminale Infiltration von Procain in narbige Gewebsareale einer enteralen Anastomosenregion nach operativem Magenhochzug.
    Type of Medium: Online Resource
    ISSN: 2504-2092 , 2504-2106
    URL: Article
    DOI: 10.1159/000495884
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2019
    detail.hit.zdb_id: 2888724-4
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  • 8
    Online Resource
    Online Resource
    Task Force - «Naturheilkunde und Komplementärmedizin in medizinischen Leitlinien»
    S. Karger AG ; 2016
    In:  Complementary Medicine Research Vol. 23, No. 3 ( 2016), p. 170-173
    Details
    In: Complementary Medicine Research, S. Karger AG, Vol. 23, No. 3 ( 2016), p. 170-173
    Abstract: Im Rahmen der aktuellen Wissenschaftskultur stellt das Bestreben, die evidenzbasierte Naturheilkunde in die Leitlinien zu integrieren, eine besondere Herausforderung dar. In Deutschland werden medizinische Leitlinien primär von den wissenschaftlichen medizinischen Fachgesellschaften und deren Dachgesellschaft, der Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften e.V. (AWMF), entwickelt und verbreitet. Bisher wird das große klinische Potential von Naturheilkunde und Komplementärmedizin an vielen Stellen nur unzureichend berücksichtigt. Mit der Aufnahme der Gesellschaft für Phytotherapie (GPT) in die AWMF wurde im Jahr 2013 ein neues Kapitel in der Leitlinienarbeit der von der Rut- und Klaus-Bahlsen-Stiftung geförderten Arbeitsgruppe «Naturheilkunde und Komplementärmedizin in medizinischen Leitlinien» aufgeschlagen. Die Bestrebung, Naturheilkunde und Komplementärmedizin fester in der konventionellen medizinischen Versorgung in Deutschland zu etablieren, bekommt damit weiter Auftrieb. Durch die Förderung der Rut- und Klaus-Bahlsen-Stiftung wurden die Mitarbeit oder Unterstützung bei bisher mehr als 20 nationalen und internationalen Leitlinien, die Erstellung von 8 Cochrane-Reviews, 4 davon federführend, und von 40 systematischen Reviews und Meta-Analysen in internationalen Peer-Review-Zeitschriften möglich. Erst durch die konsequente Ausweitung und Vollendung der begonnenen Arbeit wird eine Rückentwicklung (und Rückabwicklung) im Feld der Leitlinienarbeit unmöglich gemacht und damit die Anerkennung von Naturheilkunde und Komplementärmedizin im Fächerkanon weiter gestärkt.
    Type of Medium: Online Resource
    ISSN: 2504-2092 , 2504-2106
    URL: Article
    DOI: 10.1159/000447078
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2016
    detail.hit.zdb_id: 2888724-4
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  • 9
    Online Resource
    Online Resource
    Komplementäre Therapien in den Leitlinien für die Behandlung des Reizdarmsyndroms
    S. Karger AG ; 2015
    In:  Complementary Medicine Research Vol. 22, No. 1 ( 2015), p. 5-7
    Details
    In: Complementary Medicine Research, S. Karger AG, Vol. 22, No. 1 ( 2015), p. 5-7
    Type of Medium: Online Resource
    ISSN: 2504-2092 , 2504-2106
    URL: Article
    DOI: 10.1159/000372867
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2015
    detail.hit.zdb_id: 2888724-4
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  • 10
    Online Resource
    Online Resource
    Characteristics of Homeopathy Users among Internal Medicine Patients in Germany
    S. Karger AG ; 2016
    In:  Complementary Medicine Research Vol. 23, No. 5 ( 2016), p. 284-289
    Details
    In: Complementary Medicine Research, S. Karger AG, Vol. 23, No. 5 ( 2016), p. 284-289
    Abstract: 〈 b 〉 〈 i 〉 Background: 〈 /i 〉 〈 /b 〉 Homeopathy use continues to grow in many European countries, and some studies have examined the characteristics of patients using homeopathy within the general population. The aim of this study was to identify predictors for homeopathy use among internal medicine patients. 〈 b 〉 〈 i 〉 Patients and Methods: 〈 /i 〉 〈 /b 〉 A cross-sectional analysis was conducted among all patients being referred to the Department of Internal and Integrative Medicine at Essen, Germany, over a 3-year period. The analysis examined whether patients had used homeopathy for their primary medical complaint before, the perceived benefit, and the perceived harm of homeopathy use. Odds ratios with 95% confidence intervals were calculated using multiple logistic regression analysis. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Of 2,045 respondents, 715 (35.0%) reported having used homeopathy for their primary medical complaint (diagnosis according to the International Statistical Classification of Diseases and Related Health Problems), with 359 (50.2%) reporting perceived benefits and 15 (2.1%) reporting harm. Homeopathy use was positively associated with female gender, high school level education, suffering from fibromyalgia or subthreshold depression, and being fast food abstinent, while patients with osteoarthritis, spinal or other pain, smokers, and patients with a high external-social health locus of control were less likely to use homeopathy. 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 Personal characteristics and health status may impact on the use and the perceived helpfulness of homeopathy.
    Type of Medium: Online Resource
    ISSN: 2504-2092 , 2504-2106
    URL: Article
    DOI: 10.1159/000450818
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2016
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