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  • 1
    Online Resource
    Online Resource
    Princeton : Princeton University Press | Berlin, Germany : Walter de Gruyter GmbH
    UID:
    (DE-603)442096690
    Format: 1 Online-Ressource (xii, 223 Seiten) , Illustrationen, Diagramme
    ISBN: 9780691185118
    Series Statement: Primers in complex systems 15
    Content: How complex systems theory sheds new light on the adaptive dynamics of viral populationsViruses are everywhere, infecting all sorts of living organisms, from the tiniest bacteria to the largest mammals. Many are harmful parasites, but viruses also play a major role as drivers of our evolution as a species and are essential regulators of the composition and complexity of ecosystems on a global scale. This concise book draws on complex systems theory to provide a fresh look at viral origins, populations, and evolution, and the coevolutionary dynamics of viruses and their hosts.New viruses continue to emerge that threaten people, crops, and farm animals. Viruses constantly evade our immune systems, and antiviral therapies and vaccination campaigns can be powerless against them. These unique characteristics of virus biology are a consequence of their tremendous evolutionary potential, which enables viruses to quickly adapt to any environmental challenge. Ricard Solé and Santiago Elena present a unified framework for understanding viruses as complex adaptive systems. They show how the application of complex systems theory to viral dynamics has provided new insights into the development of AIDS in patients infected with HIV-1, the emergence of new antigenic variants of the influenza A virus, and other cutting-edge advances.Essential reading for biologists, physicists, and mathematicians interested in complexity, Viruses as Complex Adaptive Systems also extends the analogy of viruses to the evolution of other replicators such as computer viruses, cancer, and languages.
    Note: Literaturverzeichnis Seite 203-218
    Additional Edition: 9780691158846
    Language: English
    URL: Cover
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Book
    Book
    Princeton : Princeton University Press
    UID:
    (DE-602)b3kat_BV045127814
    Format: xii, 223 Seiten , Illustrationen, Diagramme, Karte
    ISBN: 9780691158846
    Series Statement: Primers in complex systems
    Language: English
    Subjects: Biology
    RVK:
    Keywords: Viren ; Anpassung
    Library Location Call Number Volume/Issue/Year Availability
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  • 3
    Book
    Book
    Princeton : Princeton University Press
    UID:
    (DE-604)BV045127814
    Format: xii, 223 Seiten , Illustrationen, Diagramme, Karte
    ISBN: 9780691158846
    Series Statement: Primers in complex systems
    Language: English
    Subjects: Biology
    RVK:
    Keywords: Viren ; Anpassung
    Library Location Call Number Volume/Issue/Year Availability
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  • 4
    UID:
    (DE-627)1645139204
    Format: xii, 223 Seiten , Illustrationen, Diagramme, Karten
    ISBN: 9780691158846
    Series Statement: Primers in complex systems
    Note: Literaturangaben, Index
    Additional Edition: 9780691185118
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 5
    Online Resource
    Online Resource
    Princeton, NJ : Princeton University Press
    UID:
    (DE-627)1658530268
    Format: 1 Online-Ressource
    ISBN: 9780691185118
    Series Statement: Primers in Complex Systems 6
    Content: How complex systems theory sheds new light on the adaptive dynamics of viral populationsViruses are everywhere, infecting all sorts of living organisms, from the tiniest bacteria to the largest mammals. Many are harmful parasites, but viruses also play a major role as drivers of our evolution as a species and are essential regulators of the composition and complexity of ecosystems on a global scale. This concise book draws on complex systems theory to provide a fresh look at viral origins, populations, and evolution, and the coevolutionary dynamics of viruses and their hosts.New viruses continue to emerge that threaten people, crops, and farm animals. Viruses constantly evade our immune systems, and antiviral therapies and vaccination campaigns can be powerless against them. These unique characteristics of virus biology are a consequence of their tremendous evolutionary potential, which enables viruses to quickly adapt to any environmental challenge. Ricard Solé and Santiago Elena present a unified framework for understanding viruses as complex adaptive systems. They show how the application of complex systems theory to viral dynamics has provided new insights into the development of AIDS in patients infected with HIV-1, the emergence of new antigenic variants of the influenza A virus, and other cutting-edge advances.Essential reading for biologists, physicists, and mathematicians interested in complexity, Viruses as Complex Adaptive Systems also extends the analogy of viruses to the evolution of other replicators such as computer viruses, cancer, and languages.
    Language: English
    URL: Cover  (lizenzpflichtig)
    Library Location Call Number Volume/Issue/Year Availability
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  • 6
    Online Resource
    Online Resource
    Princeton : Princeton University Press
    UID:
    (DE-627)1042526761
    Format: 1 Online-Ressource (239 pages)
    ISBN: 9780691185118
    Series Statement: Primers in Complex Systems Ser v.6
    Content: Cover -- Title -- Copyright -- CONTENTS -- Preface -- 1. The Virosphere -- 1.1 Deep Microspace Field -- 1.2 The Expanding Viral Universe -- 1.3 Structural and Genetic Diversity -- 1.4 Viral Planet -- 2. Alive or Dead? -- 2.1 Computation and Life -- 2.2 Viruses as Replicating Machines -- 2.3 Viruses as Phases of Matter -- 2.4 Evolving Genome Reduction -- 2.5 The Space of Replicators -- 2.6 Adaptation at High Mutation Rates -- 2.7 Viral Quasispecies -- 2.8 Critical Genome Size -- 3. Landscapes -- 3.1 Climbing High -- 3.2 Symmetric Competition -- 3.3 Epistasis in RNA Viruses -- 3.4 Experimental Virus Landscapes -- 3.5 The Survival of the Flattest Effect -- 3.6 Virus Robustness -- 3.6.1 Intrinsic Mechanisms of Mutational Robustness -- 3.6.2 Extrinsic Mechanisms of Mutational Robustness -- 3.7 Selection: Fitness versus Robustness -- 4. Virus Dynamics and Arms Races -- 4.1 Virus-Host Interactions -- 4.2 HIV Multiscale Dynamics -- 4.3 Population Dynamics of HIV Infection -- 4.4 Spatial Dynamics of HIV-1 -- 4.5 Antigenic Diversity Thresholds and AIDS -- 4.6 Viral Symbiosis -- 5. Epidemics -- 5.1 Outbreak -- 5.2 SIS Model -- 5.3 SIS Model in Space and Graphs -- 5.4 AIDS: Modeling HIV-1 Transmission -- 5.5 Halting Viruses in Scale-Free Networks -- 6. Emergent Viruses -- 6.1 Ecological Disturbance: Hanta- and Arenaviruses as Case Studies -- 6.2 The Genetics of Adaptation to Novel Host -- 6.2.1 Becoming Specialists -- 6.2.2 Becoming Generalists -- 6.2.3 The Causes of Specialization -- 6.3 Epidemics of Emergence -- 7. Origins -- 7.1 Are Viruses Inevitable? -- 7.2 Evidence from Digital Evolution -- 7.3 Where Do Viruses Come From? -- 7.3.1 Regressive Hypothesis -- 7.3.2 Cellular Origin Hypothesis -- 7.3.3 Protobiont Hypothesis -- 7.4 Viruses and the Origin of Cells -- 7.5 Viruses as Sources of Evolutionary Novelties -- 7.6 But . . . What Is a Virus Then?
    Content: 8. Computer Viruses and Beyond -- 8.1 Viruses as Programs -- 8.2 Emergence of Computer Viruses -- 8.3 Cancer, Languages, and Minds -- References -- Index
    Additional Edition: 9780691158846
    Additional Edition: Print version Solé, Ricard Viruses As Complex Adaptive Systems Princeton : Princeton University Press,c2018 9780691158846
    Language: English
    URL: Volltext  (lizenzpflichtig)
    Library Location Call Number Volume/Issue/Year Availability
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  • 7
    Online Resource
    Online Resource
    Princeton, NJ : Princeton University Press
    UID:
    (DE-604)BV045915795
    Format: 1 online resource
    ISBN: 9780691185118
    Series Statement: Primers in Complex Systems 6
    Content: How complex systems theory sheds new light on the adaptive dynamics of viral populationsViruses are everywhere, infecting all sorts of living organisms, from the tiniest bacteria to the largest mammals. Many are harmful parasites, but viruses also play a major role as drivers of our evolution as a species and are essential regulators of the composition and complexity of ecosystems on a global scale. This concise book draws on complex systems theory to provide a fresh look at viral origins, populations, and evolution, and the coevolutionary dynamics of viruses and their hosts.New viruses continue to emerge that threaten people, crops, and farm animals. Viruses constantly evade our immune systems, and antiviral therapies and vaccination campaigns can be powerless against them. These unique characteristics of virus biology are a consequence of their tremendous evolutionary potential, which enables viruses to quickly adapt to any environmental challenge. Ricard Solé and Santiago Elena present a unified framework for understanding viruses as complex adaptive systems. They show how the application of complex systems theory to viral dynamics has provided new insights into the development of AIDS in patients infected with HIV-1, the emergence of new antigenic variants of the influenza A virus, and other cutting-edge advances.Essential reading for biologists, physicists, and mathematicians interested in complexity, Viruses as Complex Adaptive Systems also extends the analogy of viruses to the evolution of other replicators such as computer viruses, cancer, and languages
    Note: Description based on online resource; title from PDF title page (publisher's Web site, viewed 07. Dez 2018) , In English
    Language: English
    Keywords: Viren ; Anpassung
    URL: Volltext  (URL des Erstveröffentlichers)
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    Online Resource
    Online Resource
    Princeton, NJ : Princeton University Press
    UID:
    (DE-605)HT020718885
    Format: 1 online resource
    ISBN: 9780691185118
    Series Statement: Primers in Complex Systems 15
    Content: How complex systems theory sheds new light on the adaptive dynamics of viral populationsViruses are everywhere, infecting all sorts of living organisms, from the tiniest bacteria to the largest mammals. Many are harmful parasites, but viruses also play a major role as drivers of our evolution as a species and are essential regulators of the composition and complexity of ecosystems on a global scale. This concise book draws on complex systems theory to provide a fresh look at viral origins, populations, and evolution, and the coevolutionary dynamics of viruses and their hosts.New viruses continue to emerge that threaten people, crops, and farm animals. Viruses constantly evade our immune systems, and antiviral therapies and vaccination campaigns can be powerless against them. These unique characteristics of virus biology are a consequence of their tremendous evolutionary potential, which enables viruses to quickly adapt to any environmental challenge. Ricard Solé and Santiago Elena present a unified framework for understanding viruses as complex adaptive systems. They show how the application of complex systems theory to viral dynamics has provided new insights into the development of AIDS in patients infected with HIV-1, the emergence of new antigenic variants of the influenza A virus, and other cutting-edge advances.Essential reading for biologists, physicists, and mathematicians interested in complexity, Viruses as Complex Adaptive Systems also extends the analogy of viruses to the evolution of other replicators such as computer viruses, cancer, and languages
    Language: English
    URL: Cover
    Library Location Call Number Volume/Issue/Year Availability
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  • 9
    Online Resource
    Online Resource
    Princeton : Princeton University Press | Oxford : Oxford University Press
    UID:
    (DE-603)510305962
    Format: 1 Online-Ressource , Illustrations (black and white).
    ISBN: 9780691185118
    Series Statement: Princeton scholarship online
    Content: Viruses are everywhere, infecting all sorts of living organisms, from the tiniest bacteria to the largest mammals. Many are harmful parasites, but viruses also play a major role as drivers of our evolution as a species and are essential regulators of the composition and complexity of ecosystems on a global scale. This text draws on complex systems theory to provide a fresh look at viral origins, populations, and evolution, and the coevolutionary dynamics of viruses and their hosts.
    Note: Previously issued in print: 2018 , Includes bibliographical references and index
    Additional Edition: 9780691158846
    Language: English
    Library Location Call Number Volume/Issue/Year Availability
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  • 10
    Online Resource
    Online Resource
    Princeton, NJ : Princeton University Press
    UID:
    (DE-602)b3kat_BV045915795
    Format: 1 online resource
    ISBN: 9780691185118
    Series Statement: Primers in Complex Systems 6
    Content: How complex systems theory sheds new light on the adaptive dynamics of viral populationsViruses are everywhere, infecting all sorts of living organisms, from the tiniest bacteria to the largest mammals. Many are harmful parasites, but viruses also play a major role as drivers of our evolution as a species and are essential regulators of the composition and complexity of ecosystems on a global scale. This concise book draws on complex systems theory to provide a fresh look at viral origins, populations, and evolution, and the coevolutionary dynamics of viruses and their hosts.New viruses continue to emerge that threaten people, crops, and farm animals. Viruses constantly evade our immune systems, and antiviral therapies and vaccination campaigns can be powerless against them. These unique characteristics of virus biology are a consequence of their tremendous evolutionary potential, which enables viruses to quickly adapt to any environmental challenge. Ricard Solé and Santiago Elena present a unified framework for understanding viruses as complex adaptive systems. They show how the application of complex systems theory to viral dynamics has provided new insights into the development of AIDS in patients infected with HIV-1, the emergence of new antigenic variants of the influenza A virus, and other cutting-edge advances.Essential reading for biologists, physicists, and mathematicians interested in complexity, Viruses as Complex Adaptive Systems also extends the analogy of viruses to the evolution of other replicators such as computer viruses, cancer, and languages
    Note: Description based on online resource; title from PDF title page (publisher's Web site, viewed 07. Dez 2018) , In English
    Language: English
    Keywords: Viren ; Anpassung
    URL: Volltext  (URL des Erstveröffentlichers)
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
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