In:
Journal of Biomedical Nanotechnology, American Scientific Publishers, Vol. 15, No. 10 ( 2019-10-01), p. 2100-2107
Abstract:
In this paper, an enzyme-linked immunosorbent assay (ELISA) using gold nanoparticles/metal porphyrin porous compound (Au NPs@PAF-40-Fe) as a marker was developed. Quantitative detection of C-reactive protein (CRP) was achieved by UV-visible spectrophotometry under optimal conditions.
The sensor has a good linear relationship in the range of 0.05–2000 ng/mL. The lower limit of detection was 0.017 ng/mL (S/N = 3), the linear correlation coefficient was 0.9921, and the average recovery was 100.74%. The ELISA has good selectivity and provides a sensitive way for detection of CRP.
Type of Medium:
Online Resource
ISSN:
1550-7033
DOI:
10.1166/jbn.2019.2836
Language:
English
Publisher:
American Scientific Publishers
Publication Date:
2019
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