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  • Frontiers Media SA  (33)
  • 1
    Online Resource
    Online Resource
    Frontiers Media SA ; 2024
    In:  Frontiers in Marine Science Vol. 11 ( 2024-3-22)
    In: Frontiers in Marine Science, Frontiers Media SA, Vol. 11 ( 2024-3-22)
    Abstract: During underwater operations, divers must determine their own trajectories using the Inertial Navigation System (INS) they carry to improve operational efficiency. However, the INS contains a sensor bias that is also incorporated into the quadratic integration process to obtain the displacement, resulting in trajectory drift of the divers during prolonged self-guidance. To overcome the above problem, other aids are needed to correct the accumulated error of the INS. The single-beacon Assisted Inertial Navigation (AIN) method can improve the flexibility of inertial error correction while simplifying the localization equipment, which is suitable for the INS cumulative error correction scenario of divers. However, most of the traditional single-beacon assisted correction methods do not consider the effect of acoustic line bending on hydroacoustic ranging, and at the same time, they do not consider the problem of singular or pathological coefficient matrices introduced by inertial navigation neighbor localization deviations. Based on the above two shortcomings, this paper uses the acoustic velocity profile for acoustic line tracking, combines the localization idea of Mobile Primitives (MP), and proposes an MP-based acoustic line tracking-Assisted Inertial Navigation Localization (AINL) method, which constructs a sliding time window (STW) by taking the historical positioning of divers as a virtual primitive, and combines the nonlinear optimization method for iterative optimization search as a means to improve the accuracy and stability of self-navigation of the divers.
    Type of Medium: Online Resource
    ISSN: 2296-7745
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2024
    detail.hit.zdb_id: 2757748-X
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  • 2
    Online Resource
    Online Resource
    Frontiers Media SA ; 2022
    In:  Frontiers in Marine Science Vol. 9 ( 2022-2-11)
    In: Frontiers in Marine Science, Frontiers Media SA, Vol. 9 ( 2022-2-11)
    Abstract: Monitoring the dynamics of ocean-going fishing vessels is essential for fisheries stock assessment and management. In this paper, coupled fishery and remote sensing methods were applied to propose a satellite-based fishery resource monitoring and assessment system (SFRMAS) that supported chub mackerel ( Scomber japonicus ), Pacific saury ( Cololabis saira ) and neon flying squid ( Ommastrephes bartramii ) fishing activities in the northwest Pacific. A multispecies fishing vessel database was generated in the SFRMAS using visible infrared imaging radiometer suite day/night band (VIIRS/DNB) images, automatic identification system (AIS) data and multimarine remote sensing resources. The results showed that the VIIRS/DNB vessel detection (VVD) and AIS vessel detection approaches improved the extraction accuracy of multispecies fishing vessels. A high productivity area with a higher chlorophyll a concentration had the most concentrated distribution of mackerel vessels. The widest longitudinal migrations of the neon flying squid and the latitudinal ranges of Pacific saury were highly related to sea surface temperature (SST), which was well captured by the movement of the fishing vessels. In the SFRMAS, the accuracy of detected multispecies fishing days and fishing catches was mostly between 60 and 90%, which can provide data support for fisheries stock assessment and management.
    Type of Medium: Online Resource
    ISSN: 2296-7745
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2757748-X
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  • 3
    In: Frontiers in Plant Science, Frontiers Media SA, Vol. 11 ( 2020-9-25)
    Type of Medium: Online Resource
    ISSN: 1664-462X
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2020
    detail.hit.zdb_id: 2687947-5
    detail.hit.zdb_id: 2613694-6
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  • 4
    Online Resource
    Online Resource
    Frontiers Media SA ; 2021
    In:  Frontiers in Genetics Vol. 12 ( 2021-4-8)
    In: Frontiers in Genetics, Frontiers Media SA, Vol. 12 ( 2021-4-8)
    Abstract: Background: The molybdenum cofactor (Moco) deficiency in humans results in the inactivity of molybdenum-dependent enzymes and is caused by pathogenic variants in MOCS1 ( Molybdenum cofactor synthesis 1 ), MOCS2 ( Molybdenum cofactor synthesis 2 ), and GPHN ( Gephyrin ). These genes along with MOCS3 ( Molybdenum cofactor synthesis 3 ) are involved in Moco biosynthesis and providing cofactors to Moco-dependent enzymes. Until now, there was no study to confirm that MOCS3 is a causative gene of Moco deficiency. Methods: Detailed clinical information was collected in the pedigree. The Whole-exome sequencing (WES) accompanied with Sanger sequencing validation were performed. Results: We described the clinical presentations of an infant, born to a non-consanguineous healthy family, diagnosed as having MOCS3 variants caused Moco deficiency and showing typical features of Moco deficiency including severe neurologic symptoms and cystic encephalomalacia in the brain MRI, resulting in neonatal death. Compound heterozygous variants in the MOCS3 gene were identified by WES. Positive sulfite and decreased levels of uric acid in plasma and urine were detected. Conclusion: To our knowledge, this is the first case of MOCS3 variants causing Moco deficiency. Our study may contribute to genetic diagnosis of Moco deficiency and future genetic counseling.
    Type of Medium: Online Resource
    ISSN: 1664-8021
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2021
    detail.hit.zdb_id: 2606823-0
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  • 5
    Online Resource
    Online Resource
    Frontiers Media SA ; 2023
    In:  Frontiers in Earth Science Vol. 11 ( 2023-3-1)
    In: Frontiers in Earth Science, Frontiers Media SA, Vol. 11 ( 2023-3-1)
    Abstract: Understanding the drought characteristics of mountainous areas in northwest China with sparse rainfall stations requires high precision, as well as high-resolution precipitation data. Considering the spatial relationship of precipitation and environmental factors, this study downscales Global Precipitation Measurement (GPM) and Multi-Source Weighted-Ensemble Precipitation (MSWEP) based on the geographically weighted regression (GWR) and multi-scale geographically weighted regression (MGWR) models integrated with interpolation. A high-resolution (1 km×1 km) precipitation dataset during 1979–2020 is reconstructed in the Tianshan Mountains, and the drought characteristics are analyzed by using the optimal dataset. The results show that: 1) Compared with GWR, MGWR model has higher downscaling accuracy; 2) The optimal MSWEP downscaling dataset (CC = 0.93, |BIAS| = 0.48%) compared to GPM (CC = 0.81, |BIAS| = 1.87%) is closer to the observed precipitation; 3) In the past 40 years, 71% and 9% of the Tianshan Mountains show significant wetting and drying trends respectively, and 16 drought events are identified. 4) The West subregion of the Tianshan Mountains is characterized by low frequency, long duration and high severity of drought events. The characteristics of the East are opposite to those of the West. Occasional extreme drought events occur in the North and South. This paper provides data support and method reference for the study of water-vapor balance and regional ecohydrological process in the arid area of Northwest China.
    Type of Medium: Online Resource
    ISSN: 2296-6463
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2023
    detail.hit.zdb_id: 2741235-0
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  • 6
    Online Resource
    Online Resource
    Frontiers Media SA ; 2021
    In:  Frontiers in Marine Science Vol. 8 ( 2021-6-10)
    In: Frontiers in Marine Science, Frontiers Media SA, Vol. 8 ( 2021-6-10)
    Abstract: Due to persistent fishing expansion in the China Seas over the past six decades, fisheries resources have been over-exploited; as a result, exploited fish have become smaller in size and younger in age. Marine piscivorous fish constituted a large portion of Chinese fisheries catch, long-term variability of which has rarely been investigated despite intense fishing pressure and climate change. In this study, we attempt to identify their responses to climate change and fishing activities and to provide scientific basis for sustainable exploitation of these resources. Seven taxa from pelagic to demersal species inhabiting either cold-water or warm-water were selected to represent the piscivorous fish assemblage in the China Seas. Total catch of these piscivorous fish in the China Seas increased during the early 1990s, stabilizing around 1.2 million tons after 1997. Principal component analysis (PCA) showed evident interannual-decadal variabilities in the catch of these fish with step changes around 1985/86 and 1997/98. Individual taxa, however, showed different trends in catches with sharks, rays, and lizardfishes manifesting downward trends while Pacific cod, eels, and hairtail increasing. Common dolphinfish and Japanese-Spanish mackerel increased largely in the 1990s but declined slightly during the 2000s. Although there were temporal overlaps between climate change and fishing variabilities, results of gradient forest analyses indicated that fishing effort imposed the most important influence on piscivorous fish. And among all climate variables explored in this study, sea surface temperature (SST) especially that of the East China Sea, had greatest impacts on variations in piscivorous fish catch, which may have been gradually exacerbated by the continued high fishing intensity. In addition, significant changes were identified in the life history traits in the species we evaluated, such as reduced average body sizes and truncated age compositions, strongly indicating the effect of fishing. We therefore advocate precautionary fishery practices under climate change.
    Type of Medium: Online Resource
    ISSN: 2296-7745
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2021
    detail.hit.zdb_id: 2757748-X
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  • 7
    In: Frontiers in Marine Science, Frontiers Media SA, Vol. 9 ( 2022-2-24)
    Abstract: A two-stage diet-switch experiment was conducted to examine the hypothesis that the changes in digestive enzyme activities of sea cucumber ( Apostichopus japonicus ) induced by historic diets might persist in the regenerated intestines. In stage I, A. japonicus were treated with two different diets for 56 days, including diet A with 11% crude protein, 1% crude lipid, and 40% carbohydrate, and diet B with 18% crude protein, 2% crude lipid, and 35% carbohydrate. In stage II, each treatment was subjected to evisceration with 0.35M KCl or not (eviscerated and non-eviscerated groups), half of which were then switched to different diets from diet A to B or vice versa for 112 days. The persistence of digestive enzyme activities was evaluated by measuring the changes in digestive enzyme activities before and after evisceration. In stage I, diets B and A increased trypsin and amylase activities, respectively. In stage II, the higher trypsin activities were observed in eviscerated and non-eviscerated A. japonicus that had consumed diet B in stage I. The higher amylase activities were observed only in eviscerated A. japonicus that had consumed diet A in stage I. It indicated that the historic diets showed long-term effects on the digestion of A. japonicus , which led to the persistence of changes in both trypsin and amylase activities in intestines, especially in the regenerated intestines. In addition, the specific growth rates (SGRs) and metabolic rates (MRs) of A. japonicus were affected by the long-term effects of historic diets. Meanwhile, the relationships between enzymic activities, SGRs, and MRs were observed in A. japonicus , indicating that the historic diets could produce long-term effects on the growth and metabolism of A. japonicus through their long-term effects of historic diets on digestive enzyme activities. In conclusion, the present study showed that the changes in digestive enzyme activities induced by different diets in stage I could persist in the intestines and regenerated intestines, leading to long-term effects of historic diets on the growth and metabolism of A. japonicus .
    Type of Medium: Online Resource
    ISSN: 2296-7745
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2757748-X
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  • 8
    Online Resource
    Online Resource
    Frontiers Media SA ; 2021
    In:  Frontiers in Surgery Vol. 8 ( 2021-12-2)
    In: Frontiers in Surgery, Frontiers Media SA, Vol. 8 ( 2021-12-2)
    Abstract: Masses of the inferior vena cava (IVC) are very diverse, most of which are thrombus and tumor thrombus, whereas heterotopic ossification of IVC has never been reported. Heterotopic ossification (HO) is the formation of mature lamellar bone outside normal bones and in soft tissues. Some researchers believe that HO is a manifestation of vascular calcification. Here we present a case of HO of the inferior vena cava (IVC) wall. A 68 year old female patient complaining hypertension and palpitation and diagnosed with a retroperitoneal mass was found to have a primary mass of the inferior vena cava wall during surgery. Histopathological examination after surgical resection revealed that the mass was mainly composed of mature bone tissues and hematopoietic tissues of bone marrow, there was no recurrence and the patient was symptom-free 15 months after the surgery. HO of the inferior vena cava wall is very rare, with large volume it can affect the circulation, and this case remind us that it can be cured by surgical resection.
    Type of Medium: Online Resource
    ISSN: 2296-875X
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2021
    detail.hit.zdb_id: 2773823-1
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  • 9
    Online Resource
    Online Resource
    Frontiers Media SA ; 2021
    In:  Frontiers in Molecular Biosciences Vol. 8 ( 2021-12-24)
    In: Frontiers in Molecular Biosciences, Frontiers Media SA, Vol. 8 ( 2021-12-24)
    Abstract: As one common kind of osteoporosis, postmenopausal osteoporosis (PMOP) is associated with the death and excessive loss of osteocytes. Estrogen deficiency of PMOP can cause osteocyte death by regulating necroptosis and apoptosis, but their roles in POMP have not been compared. In the present study, ovariectomy (OVX)-induced rat and murine long bone osteocyte Y4 (MLO-Y4) cells were used to compare the influence of necroptosis and apoptosis on osteocyte death and bone loss. Benzyloxycarbonyl-Val-Ala-Asp (zVAD) and necrostatin-1 (Nec-1) were used to specifically block cell apoptosis and necroptosis, respectively. OVX rats and MLO-Y4 cells were divided into zVAD group, Nec-1 group, zVAD + Nec-1 group, vehicle, and control group. The tibial plateaus of the rat model were harvested at 8 weeks after OVX and were analyzed by micro–computed tomography, transmission electron microscopy (TEM), the transferase dUTP nick end labeling assay, and western blot. The death of MLO-Y4 was stimulated by TNF-α and was measured by flow cytometry and TEM. The results found that necroptosis and apoptosis were both responsible for the death and excessive loss of osteocytes, as well as bone loss in OVX-induced osteoporosis, and furthermore necroptosis may generate greater impact on the death of osteocytes than apoptosis. Necroptotic death of osteocytes was mainly regulated by the receptor-interacting protein kinase 3 signaling pathway. Collectively, inhibition of necroptosis may produce better efficacy in reducing osteocyte loss than that of apoptosis, and combined blockade of necroptosis and apoptosis provide new insights into preventing and treating PMOP.
    Type of Medium: Online Resource
    ISSN: 2296-889X
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2021
    detail.hit.zdb_id: 2814330-9
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  • 10
    In: Frontiers in Oncology, Frontiers Media SA, Vol. 12 ( 2022-12-23)
    Abstract: Whether steroid response is an independent risk factor for acute lymphoblastic leukemia (ALL) is controversial. This study aimed to investigate the relationship between response to dexamethasone and prognosis in children with ALL. Methods We analyzed the data of 5,161 children with ALL who received treatment in accordance with the Chinese Children’s Cancer Group ALL-2015 protocol between January 1, 2015, and December 31, 2018, in China. All patients received dexamethasone for 4 days as upfront window therapy. Based on the peripheral lymphoblast count on day 5, these patients were classified into the dexamethasone good response (DGR) and dexamethasone poor response (DPR) groups. A peripheral lymphoblast count ≥1× 10 9 /L indicated poor response to dexamethasone. Results The age, white blood cell counts, prevalence of the BCR/ABL1 and TCF3/PBX1 fusion genes, and rates of recurrence in the central nervous system were higher in the DPR than in the DGR group ( P & lt;0.001). Compared to the DPR group, the DGR group had a lower recurrence rate (18.6% vs. 11%) and higher 6-year event-free survival (73% vs. 83%) and overall survival (86% vs. 92%) rates; nevertheless, subgroup analysis only showed significant difference in the intermediate-risk group ( P & lt;0.001). Discussion Response to dexamethasone was associated with an early treatment response in our study. In the intermediate-risk group, dexamethasone response added a prognostic value in addition to minimal residual disease, which may direct early intervention to reduce the relapse rate.
    Type of Medium: Online Resource
    ISSN: 2234-943X
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2649216-7
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