In:
Journal of Pediatric Neurology, Georg Thieme Verlag KG, Vol. 16, No. 03 ( 2018-06), p. 192-201
Abstract:
The recent demonstration of pathogenic immune mechanisms and autoantibodies in some patients with acute encephalopathy has raised interest in the identification of autoimmunity as a treatable cause of encephalitis. Especially in children, autoimmune encephalitis can be triggered by a preceding viral infection (e.g., anti-N-methyl-D-aspartate receptor encephalitis post-herpes simplex encephalitis) or by some acquired or genetic disorders that predispose to brain autoimmunity (e.g., hematopoietic cell transplant, CLTA4 deficiency). This review discusses recent advances in pediatric autoimmune encephalitis, including new insights into immune mechanisms and biomarkers in disorders proven or suspected to be autoimmune.
Type of Medium:
Online Resource
ISSN:
1304-2580
,
1875-9041
DOI:
10.1055/s-0037-1604477
Language:
English
Publisher:
Georg Thieme Verlag KG
Publication Date:
2018
detail.hit.zdb_id:
2130673-4
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