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  • 1
    In: Annals of Nutrition and Metabolism, S. Karger AG, Vol. 75, No. 3 ( 2019), p. 179-186
    Abstract: 〈 b 〉 〈 i 〉 Background: 〈 /i 〉 〈 /b 〉 Low-grade systematic inflammation triggers atrial wall thickening, which predisposes to several cardiovascular events. Since diet is a strong moderator of systematic inflammation, the literature review-based dietary inflammatory index (DII®) score has been recently introduced for evaluating inflammatory properties of an individual’s diet. The aim of the present study was to assess the association of DII, with carotid intima media thickness (cIMT) among overweight or obese children and adolescents. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 A total of 339 children and adolescents (48% girls) aged from 6 to 13 years, with WHO body mass index z-score & #x3e;1 were enrolled in this cross-sectional study. A valid and reliable semi-quantitative food frequency questionnaire was used to collect dietary intakes and calculate DII score. cIMT was measured in the common carotid artery with high-resolution ultrasonography. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 In this cross-sectional study, the mean ± SD age of participants was 9.3 ± 1.7 years. Among participants, 68% were obese and 83% were in the pubertal stage. DII ranged from –5.43 to 4.42, with the mean of –2.83 in the lowest, and 1.25 in the highest tertile of DII. When fit as a continuous variable, DII score had no significant association with cIMT after adjusting for potential confounders. However, the participants in the highest DII score tertile compared to the lowest had 2.46-fold increased risk of high cIMT in the multivariable adjusted model ( 〈 i 〉 p 〈 /i 〉 for trend = 0.02). 〈 b 〉 〈 i 〉 Discussion/Conclusion: 〈 /i 〉 〈 /b 〉 Higher DII scores were associated with increased risk of high cIMT.
    Type of Medium: Online Resource
    ISSN: 0250-6807 , 1421-9697
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2019
    detail.hit.zdb_id: 1481977-6
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  • 2
    Online Resource
    Online Resource
    S. Karger AG ; 2016
    In:  Neuroepidemiology Vol. 47, No. 1 ( 2016), p. 26-31
    In: Neuroepidemiology, S. Karger AG, Vol. 47, No. 1 ( 2016), p. 26-31
    Abstract: 〈 b 〉 〈 i 〉 Background: 〈 /i 〉 〈 /b 〉 Diet and inflammation have been suggested to be important risk factors for multiple sclerosis (MS). 〈 b 〉 〈 i 〉 Objectives: 〈 /i 〉 〈 /b 〉 In this study, we examined the ability of the dietary inflammatory index (DII) to predict MS in a case-control study conducted in Iran. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 This study included 68 MS cases and 140 controls hospitalized for acute non-neoplastic diseases. The DII was computed based on dietary intake assessed by a previously validated food frequency questionnaire. Logistic regression models were used to estimate ORs adjusted for age, energy, sex, body mass index, season of birth, rubella history, history of routine exercise before MS, smoking and history of consumption of cow's milk in the first 2 years of life. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Subjects with higher DII scores (i.e., with a more pro-inflammatory diet) had a higher risk of MS, with the DII being used both as a continuous variable (OR 〈 sub 〉 continuous 〈 /sub 〉 1.66; 95% CI 1.19-2.31; 1 unit increase corresponding to ≈15% of its range in the current study) and a categorical variable (OR 〈 sub 〉 DII ( 〉 1.43 vs. 〈 /sub 〉 〈 sub 〉 ≤ 〈 /sub 〉 〈 sub 〉 1.43) 〈 /sub 〉 2.68; 95% CI 1.15-6.26). 〈 b 〉 〈 i 〉 Conclusions: 〈 /i 〉 〈 /b 〉 These results indicate that a pro-inflammatory diet is associated with increased risk of MS.
    Type of Medium: Online Resource
    ISSN: 0251-5350 , 1423-0208
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2016
    detail.hit.zdb_id: 1483032-2
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