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  • SAGE Publications  (52)
  • 1
    Online Resource
    Online Resource
    Removal of Tracheobronchial Foreign Bodies via Suspension Laryngoscope and Hopkins Telescope in Infants
    SAGE Publications ; 2011
    In:  Annals of Otology, Rhinology & Laryngology Vol. 120, No. 7 ( 2011-07), p. 484-488
    Details
    In: Annals of Otology, Rhinology & Laryngology, SAGE Publications, Vol. 120, No. 7 ( 2011-07), p. 484-488
    Abstract: Tracheobronchial foreign body aspiration is a life-threatening accident in infants, and is still a formidable clinical emergency to both otorhinolaryngologists and anesthesiologists. In this study, we attempted to assess the safety and ease of tracheobronchial foreign body removal in infants via suspension laryngoscopy and Hopkins telescopy under general anesthesia with endotracheal intubation. Methods: The retrospective clinical study from 2006 to 2010 included 50 infants with foreign body aspiration, of whom 35 underwent suspension laryngoscopy and Hopkins telescopy and the other 15 underwent rigid bronchoscopy. All of the procedures were under general anesthesia with endotracheal intubation. Results: All of the patients underwent temporary extubation. The foreign body was successfully removed in 46 cases and was not found in the other 4 cases. The mean operation time in the rigid bronchoscopy group was 13.20 ± 9.01 minutes, and that in the Hopkins telescopy group was 5.79 ± 3.54 minutes. The oxygen saturation level was below 90% in 17 cases, of which 7 were in the rigid bronchoscopy group and 10 were in the Hopkins telescopy group. The vital signs, including the partial pressure of carbon dioxide in expiratory gas and the heart rate, were stable in all cases. Conclusions: Foreign body removal in infants via suspension laryngoscopy and Hopkins telescopy under general anesthesia with endotracheal intubation should be promoted, since it is relatively safe and easy for both anesthesiologists and otorhinolaryngologists to perform and has a remarkable success rate.
    Type of Medium: Online Resource
    ISSN: 0003-4894 , 1943-572X
    URL: Article
    DOI: 10.1177/000348941112000711
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2011
    detail.hit.zdb_id: 2033055-8
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  • 2
    Online Resource
    Online Resource
    Study on decomposition and calculation method of EPS assist characteristic curve
    SAGE Publications ; 2021
    In:  Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering Vol. 235, No. 8 ( 2021-07), p. 2166-2175
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering, SAGE Publications, Vol. 235, No. 8 ( 2021-07), p. 2166-2175
    Abstract: Steering feel is closely related to the matching of the EPS assist characteristic curve, however, due to the lack of theoretical basis for the design of the EPS assist characteristic curve, the steering feel can only be changed indirectly by adjusting the magnitude of assist, which is very difficult. To control steering feel directly and reduce the difficulty of adjustment, this paper proposes a decomposition and calculation method of the EPS assist characteristic curve. At first, the mechanism of the EPS assist characteristic curve is revealed. It is found that the process of designing and adjusting the EPS assist characteristic curve is a process of changing the corresponding relationship between the steering wheel torque and the steering motion intensity based on considering vehicle dynamic characteristics. On this basis, the driver’s desired steering motion intensity and the pinion angle position are taken as intermediate variables, the EPS assist characteristic curve is decomposed into three parts: driving style, steady-state inverse characteristics of chassis dynamics, and steady-state inverse characteristics of steering system dynamics. According to the designed driving style and the calibrated steady-state inverse characteristics of chassis dynamics and steering system dynamics, the EPS assist characteristic curve can be directly calculated. The test results show that the EPS system adopting assist characteristic curve calculated can realize the designed driving style and provide consistent and controllable steering feel on the premise of meeting the requirements of steering portability and road feel.
    Type of Medium: Online Resource
    ISSN: 0954-4070 , 2041-2991
    URL: Article
    DOI: 10.1177/0954407020987062
    RVK:
    ZO 4200
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2032754-7
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  • 3
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    Online Resource
    Safety and Immunogenicity from a Phase I Trial of Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine
    SAGE Publications ; 2007
    In:  Antiviral Therapy Vol. 12, No. 7 ( 2007-10), p. 1107-1114
    Details
    In: Antiviral Therapy, SAGE Publications, Vol. 12, No. 7 ( 2007-10), p. 1107-1114
    Abstract: Emergence of severe acute respiratory syndrome (SARS) from the winter of 2002 to the spring of 2003 has caused a serious threat to public health. Methods To evaluate the safety and immunogenicity of the inactivated SARS coronavirus (SARS-CoV) vaccine, 36 subjects received two doses of 16 SARS-CoV units (SU) or 32 SU inactivated SARS-CoV vaccine, or placebo control. Results On day 42, the seroconversion reached 100% for both vaccine groups. On day 56, 100% of participants in the group receiving 16 SU and 91.1% in the group receiving 32 SU had seroconverted. The geometric mean titre of neutralizing antibody peaked 2 weeks after the second vaccination, but decreased 4 weeks later. Conclusion The inactivated vaccine was safe and well tolerated and can elicit SARS-CoV-specific neutralizing antibodies.
    Type of Medium: Online Resource
    ISSN: 1359-6535 , 2040-2058
    URL: Article
    DOI: 10.1177/135965350701200702
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2007
    detail.hit.zdb_id: 2118396-X
    SSG: 15,3
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  • 4
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    Online Resource
    Response: Methodological Issue on Prediction of Emergency Cesarean Section by Measurable Maternal and Fetal Characteristics
    SAGE Publications ; 2020
    In:  Journal of Investigative Medicine Vol. 68, No. 5 ( 2020-06), p. 1025-1025
    Details
    In: Journal of Investigative Medicine, SAGE Publications, Vol. 68, No. 5 ( 2020-06), p. 1025-1025
    Type of Medium: Online Resource
    ISSN: 1081-5589 , 1708-8267
    URL: Article
    DOI: 10.1136/jim-2020-001404
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
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  • 5
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    Distinct cerebral 18 F-FDG PET metabolic patterns in anti-N-methyl-D-aspartate receptor encephalitis patients with different trigger factors
    SAGE Publications ; 2021
    In:  Therapeutic Advances in Neurological Disorders Vol. 14 ( 2021-01), p. 175628642199563-
    Details
    In: Therapeutic Advances in Neurological Disorders, SAGE Publications, Vol. 14 ( 2021-01), p. 175628642199563-
    Abstract: Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a subgroup of treatable autoimmune encephalitis, characterized by rapid development of psychosis, cognitive impairments and seizures. Etiologically, anti-NMDAR encephalitis could be divided into three subgroups, which are paraneoplastic (especially associated with ovarian teratoma), viral encephalitis-related and cryptogenic. Each type is different in clinical course, treatment strategies and prognosis. In this study, we aim to investigate whether anti-NMDAR encephalitis patients with different trigger factors exhibit distinct cerebral metabolic patterns detected by 18 F-fluorodeoxyglucose positron emission tomography imaging. Methods: 24 patients with anti-NMDAR encephalitis in acute phase from Huashan Hospital, Fudan University (Shanghai, China) were recruited in this study. Each patient was classified into one of etiological subgroups. Positron emission tomography images of individual patients were analyzed with both routine visual reading and computer-supported reading by comparison with those of the same 10 healthy controls using a voxel-wise statistical parametric mapping analysis. Results: Patients in both the cryptogenic (13 patients) and paraneoplastic (five patients) subgroups showed hypermetabolism in the frontal-temporal lobes and basal ganglia, covarying with hypometabolism in the occipital regions. Notably, the abnormal metabolism was usually asymmetric in the cryptogenic subgroup, but relatively symmetric in the paraneoplastic subgroup. Moreover, the other six patients secondary to viral encephalitis presented with significant hypometabolism in the bilateral occipital regions, as well as in the unilateral temporal lobes and part of basal ganglia (also is virus infection side), but hypermetabolism in the contralateral temporal areas. Conclusion: This study revealed that patients with anti-NMDAR encephalitis triggered by different factors presented distinct cerebral metabolic patterns. Awareness of these patterns may help to better understand the varying occurrence and development of anti-NMDAR encephalitis in each subgroup, and could offer valuable information to the early diagnosis, treatment and prognosis of this disorder. Trial registration number ChiCTR2000029115 (Chinese clinical trial registry site, http://www.chictr.org )
    Type of Medium: Online Resource
    ISSN: 1756-2864 , 1756-2864
    URL: Article
    DOI: 10.1177/1756286421995635
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2442245-9
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  • 6
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    Cold Ischemia Score: An mRNA Assay for the Detection of Extended Cold Ischemia in Formalin-Fixed, Paraffin-Embedded Tissue
    SAGE Publications ; 2019
    In:  Journal of Histochemistry & Cytochemistry Vol. 67, No. 3 ( 2019-03), p. 159-168
    Details
    In: Journal of Histochemistry & Cytochemistry, SAGE Publications, Vol. 67, No. 3 ( 2019-03), p. 159-168
    Abstract: Although there are thousands of formalin-fixed paraffin-embedded (FFPE) tissue blocks potentially available for scientific research, many are of questionable quality, partly due to unknown preanalytical variables. We analyzed FFPE tissue biospecimens as part of the National Cancer Institute (NCI) Biospecimen Preanalytical Variables program to identify mRNA markers denoting cold ischemic time. The mRNA was extracted from colon, kidney, and ovary cancer FFPE blocks (40 patients, 10–12 hr fixation time) with 1, 2, 3, and 12 hr cold ischemic times, then analyzed using qRT-PCR for 23 genes selected following a literature search. No genes tested could determine short ischemic times (1–3 hr). However, a combination of three unstable genes normalized to a more stable gene could generate a “Cold Ischemia Score” that could distinguish 1 to 3 hr cold ischemia from 12 hr cold ischemia with 62% sensitivity and 84% specificity.
    Type of Medium: Online Resource
    ISSN: 0022-1554 , 1551-5044
    URL: Article
    DOI: 10.1369/0022155418819967
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 1421306-0
    SSG: 12
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  • 7
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    Online Resource
    Effects of T-2 toxin on the regulation of steroidogenesis in mouse Leydig cells
    SAGE Publications ; 2016
    In:  Toxicology and Industrial Health Vol. 32, No. 10 ( 2016-10), p. 1801-1807
    Details
    In: Toxicology and Industrial Health, SAGE Publications, Vol. 32, No. 10 ( 2016-10), p. 1801-1807
    Abstract: T-2 toxin is one of the mycotoxins, a group of type A trichothecenes produced by several fungal genera including Fusarium species, which may lead to the decrease of testosterone secretion in primary Leydig cells derived from mouse testis. The previous study demonstrated T-2 toxin decrease the testosterone biosynthesis in the primary Leydig cells derived from the mouse testis directly. In this study, we further examined the direct biological effects of T-2 toxin on the process of steroidogenesis, primarily in Leydig cells of mice. Leydig cells of mature mouse were purified by Percoll gradient centrifugation and the cell purity was determined by 3β-hydroxysteroid dehydrogenase (3β-HSD) staining. To examine the decrease in T-2 toxin-induced testosterone secretion, we measured the transcription level of three key steroidogenic enzymes including 3β-HSD-1, cytochrome P450 side-chain cleavage (P450scc) enzyme, and steroidogenic acute regulatory (StAR) protein in T-2 toxin/human chorionic gonadotropin (hCG) co-treated cells. Our previous study showed that T-2 toxin (10 −7 , 10 −8 , and 10 −9 M) significantly suppressed hCG (10 ng/ml)-induced testosterone secretion. The studies demonstrated that the suppressive effect is correlated with a decrease in the level of transcription of 3β-HSD-1, P450scc, and StAR ( p 〈 0.05).
    Type of Medium: Online Resource
    ISSN: 0748-2337 , 1477-0393
    URL: Article
    DOI: 10.1177/0748233715590516
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2010891-6
    SSG: 12
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  • 8
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    Online Resource
    Cognitive stimulation therapy in the treatment of neuropsychiatric symptoms in Alzheimer’s disease: a randomized controlled trial
    SAGE Publications ; 2010
    In:  Clinical Rehabilitation Vol. 24, No. 12 ( 2010-12), p. 1102-1111
    Details
    In: Clinical Rehabilitation, SAGE Publications, Vol. 24, No. 12 ( 2010-12), p. 1102-1111
    Abstract: Objective: To determine the efficacy of cognitive stimulation therapy (CST) in the treatment of neuropsychiatric symptoms in patients with Alzheimer’s disease. Design: A randomized, controlled, rater-blind clinical trial. Setting: The military sanatorium. Subjects: Thirty-two patients with mild to moderate Alzheimer’s disease exhibiting marked neuropsychiatric symptoms were included in the study. Intervention: All 32 patients were randomly assigned to a cognitive stimulation therapy group (n = 16) or a control group (n = 16) for 10 weeks. Main measure: The efficacy measures included the Mini Mental State Examination and the Neuropsychiatric Inventory. Results: Patients receiving cognitive stimulation therapy showed a greater improvement in the Neuropsychiatric Inventory total score (mean change — 2.06 points versus 0.00 points, t = -4.766, P 〈 0.001) and in the Mini Mental State Examination total score (mean change 0.81 points versus —0.19 points, t =3.106, P =0.004) compared to control at week 10. Analysis of the individual Neuropsychiatric Inventory domains revealed a statistically significant benefit for cognitive stimulation therapy-treated patients in the areas of apathy (mean change —1.06 points versus —0.31 points, P =0.017) and depression/dysphoria (mean change —0.50 points versus 0.06 points, P =0.047). There were no statistically significant benefits for cognitive stimulation therapy-treated patients in the other individual Neuropsychiatric Inventory domains or in the caregiver distress score. Conclusions: Cognitive stimulation therapy has significant efficacy in lowering apathy and depression symptomatology and in the Mini Mental State Examination in patients with mild to moderate Alzheimer’s disease.
    Type of Medium: Online Resource
    ISSN: 0269-2155 , 1477-0873
    URL: Article
    DOI: 10.1177/0269215510376004
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2010
    detail.hit.zdb_id: 2028323-4
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  • 9
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    Junior high school students’ achievement goals, social goals, and self-reported persistence in physical education settings
    SAGE Publications ; 2020
    In:  European Physical Education Review Vol. 26, No. 1 ( 2020-02), p. 218-230
    Details
    In: European Physical Education Review, SAGE Publications, Vol. 26, No. 1 ( 2020-02), p. 218-230
    Abstract: This study utilized a 2 × 2 achievement goal model to explore a relationship between achievement goals and social goals, and how these goals are associated with junior high school students’ self-reported persistence toward physical activities. A total of 246 students from four junior high schools participated in the study. The results revealed that mastery-approach goals, social responsibility goals, and performance-approach goals were significantly positive predictors of persistence, whereas mastery-avoidance goals, performance-avoidance goals, and social relationship goals were not significant predictors of persistence. Additionally, girls scored significantly higher values on social relationship, social responsibility, and mastery-avoidance goals than boys, whereas boys reported significantly higher values on performance-approach goals than girls. Findings provide empirical support to the view that both achievement goals and social goals should be used to examine student motivation and achievement in junior high school physical education settings while considering gender differences.
    Type of Medium: Online Resource
    ISSN: 1356-336X , 1741-2749
    URL: Article
    DOI: 10.1177/1356336X19846912
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2025496-9
    SSG: 31
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  • 10
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    Students’ ability beliefs about running in physical education: Qualitative findings from longitudinal data
    SAGE Publications ; 2021
    In:  European Physical Education Review Vol. 27, No. 2 ( 2021-05), p. 348-365
    Details
    In: European Physical Education Review, SAGE Publications, Vol. 27, No. 2 ( 2021-05), p. 348-365
    Abstract: Students’ ability beliefs about running activities in physical education/athletics classes were investigated longitudinally from the perspectives of Nicholls’ conceptions of ability and Dweck’s implicit theories of ability. The data for this study were provided by 44 students (20 boys; 24 girls) who participated in a larger longitudinal project on students’ running motivation in schools. They were individually interviewed from fourth to eighth grade. All interviews were tape-recorded and transcribed verbatim for inductive analysis, revealing the criteria that students used to assess their own ability in running and reasons why they believed they could improve their ability in running. Frequencies and percentages were computed to determine changes in students’ ability assessment criteria over time. Results showed that students used ability, effort, task mastery, intra-individual comparisons, and social comparisons as criteria to assess their own ability in running as they progressed from the fourth to eighth grade. However, they increasingly used social comparison in assessment as they became older. Most students believed they could improve their ability in running, suggesting that they were incremental theorists. Ability/maturation, effort, experiences, and influences from significant others were cited as contributors to their beliefs about improving running ability. This study took the first step to provide longitudinal qualitative data on students’ ability beliefs about running in physical education/athletics classes. Findings of the study revealed students became more concerned with social comparisons in their ability assessments over time and held a belief that they could improve their own running ability. The implications of these findings for physical education teachers are discussed.
    Type of Medium: Online Resource
    ISSN: 1356-336X , 1741-2749
    URL: Article
    DOI: 10.1177/1356336X20949902
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2025496-9
    SSG: 31
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