In:
Journal of Cell Science, The Company of Biologists, Vol. 104, No. 4 ( 1993-04-01), p. 949-955
Abstract:
Over the last few years a number of international meetings have boasted titles along the lines of “from receptor to nucleus” reflecting a desire to construct a pathway linking the endpoints of different regulatory events. However, for historical and technical reasons, research effort has been focused overwhelmingly on receptor/ligand or transcription factor/DNA interactions. The task confronting biologists now is to link up these two extremes. Our present under-standing of these intermediary processes is in many cases rudimentary, but it is clear that signal transduction from membrane to nucleus often involves many steps, and it also appears that several pathways can use common intermediates, which raises interesting questions in speed and specificity.
Type of Medium:
Online Resource
ISSN:
0021-9533
,
1477-9137
DOI:
10.1242/jcs.104.4.949
Language:
English
Publisher:
The Company of Biologists
Publication Date:
1993
detail.hit.zdb_id:
219171-4
detail.hit.zdb_id:
1483099-1
SSG:
12
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