In:
Journal of Diabetes Investigation, Wiley, Vol. 7, No. 5 ( 2016-09), p. 689-694
Abstract:
To clarify the association of the hypertriglyceridemic waist phenotype and type 2 diabetes mellitus among adults in China. Materials and Methods In the present case–control study, we included 1,685 patients with type 2 diabetes mellitus and 7,141 normal glucose‐tolerant controls from the Henan Province of China in 2011. Elevated waist circumference ( GW ) was defined as ≥90 cm for men and ≥80 cm for women. Hypertriglyceridemia ( HT ) was defined as 〉 1.7 m mol/L triglycerides ( TG ) level. The association of hypertriglyceridemic waist phenotype and type 2 diabetes mellitus was investigated by sex, body mass index, physical activity, and family history of diabetes. Results Cases and controls differed in age, waist circumference ( WC ), weight, TG level, fasting glucose, body mass index, smoking status, diabetic family history, physical activity and hypertriglyceridemic waist phenotype ( P 〈 0.05), but not alcohol drinking ( P = 0.63). In the overall sample, as compared with the phenotype of normal TG level and normal WC ( NTNW ), normal TG level/enlarged WC ( NTGW ), elevated TG level/normal WC ( HTNW ) and elevated TG level/enlarged WC ( HTGW ) were associated with type 2 diabetes mellitus (odds ratio 4.14, 2.42 and 6.23, respectively). Only HTGW was consistently associated with risk of type 2 diabetes mellitus, with or without adjustment. The strongest relationship between HTGW and type 2 diabetes mellitus was for subjects with body mass index 〈 24.0 kg/m 2 (odds ratio 6.54, 95% confidence interval 4.22–10.14) after adjustment for cofounding variables. Conclusion HTGW was stably and significantly associated with risk of type 2 diabetes mellitus in adult Chinese.
Type of Medium:
Online Resource
ISSN:
2040-1116
,
2040-1124
DOI:
10.1111/jdi.2016.7.issue-5
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
2542077-X
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