In:
PLOS ONE, Public Library of Science (PLoS), Vol. 17, No. 3 ( 2022-3-31), p. e0265529-
Abstract:
The COVID-19 pandemic has spread worldwide, and almost 396 million people have been infected around the globe. Latin American countries have been deeply affected, and there is a lack of data in this regard. This study aims to identify the clinical characteristics, in-hospital outcomes, and factors associated with ICU admission due to COVID-19. Furthermore, to describe the functional status of patients at hospital discharge after the acute episode of COVID-19. Material and methods This was a prospective, multicenter, multinational observational cohort study of subjects admitted to 22 hospitals within Latin America. Data were collected prospectively. Descriptive statistics were used to characterize patients, and multivariate regression was carried out to identify factors associated with severe COVID-19. Results A total of 3008 patients were included in the study. A total of 64.3% of patients had severe COVID-19 and were admitted to the ICU. Patients admitted to the ICU had a higher mean (SD) 4C score (10 [3] vs. 7 [3)] , p 〈 0.001). The risk factors independently associated with progression to ICU admission were age, shortness of breath, and obesity. In-hospital mortality was 24.1%, whereas the ICU mortality rate was 35.1%. Most patients had equal self-care ability at discharge 43.8%; however, ICU patients had worse self-care ability at hospital discharge (25.7% [497/1934] vs. 3.7% [40/1074] , p 〈 0.001). Conclusions This study confirms that patients with SARS CoV-2 in the Latin American population had a lower mortality rate than previously reported. Systemic complications are frequent in patients admitted to the ICU due to COVID-19, as previously described in high-income countries.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0265529
DOI:
10.1371/journal.pone.0265529.g001
DOI:
10.1371/journal.pone.0265529.g002
DOI:
10.1371/journal.pone.0265529.t001
DOI:
10.1371/journal.pone.0265529.t002
DOI:
10.1371/journal.pone.0265529.t003
DOI:
10.1371/journal.pone.0265529.s001
DOI:
10.1371/journal.pone.0265529.s002
DOI:
10.1371/journal.pone.0265529.s003
DOI:
10.1371/journal.pone.0265529.s004
DOI:
10.1371/journal.pone.0265529.r001
DOI:
10.1371/journal.pone.0265529.r002
DOI:
10.1371/journal.pone.0265529.r003
DOI:
10.1371/journal.pone.0265529.r004
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2022
detail.hit.zdb_id:
2267670-3
Bookmarklink