Format:
3
ISSN:
1523-5866
Content:
A better understanding of the biological evolution of gliomas and its modulation by therapeutic interventions has become a central topic.1,2 However, little is known about the natural evolution of glioblastoma treated by surgery alone. Glioblastoma patients are almost always treated with radiotherapy or chemotherapy, and if not, rarely undergo second surgery.Here, we report a series of 5 glioblastoma patients (pts), who did not undergo treatment beyond surgery, but had second surgery for recurrent disease after a median of 66 days (range, 36-128 days): 128 days (pt 1); 66 days (pt 2); 95 days (pt 3); 36 days (pt 4); 38 days (pt 5). Reasons included patient wish (pts 1, 2, 3) or early progression detected during radiotherapy planning (pts 4, 5). All patients had gross total resection at first surgery followed by another gross total (pts 1, 3, 4) or partial resection (〈99%) (pts 2, 5) at recurrence. Median age at diagnosis was 63 years (range, 50-72 y). Three patients were included in a previous study.2 This study was approved by the Ethics Committee of the Canton of Zurich.
Note:
Gesehen am 02.06.2021
,
First published: 11 November 2020
In:
Neuro-Oncology, Oxford : Oxford Univ. Press, 1999, 23(2021), 2 vom: Feb., Seite 334-336, 1523-5866
In:
volume:23
In:
year:2021
In:
number:2
In:
month:02
In:
pages:334-336
In:
extent:3
Language:
English
DOI:
10.1093/neuonc/noaa261
URL:
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