In:
Journal of Biophotonics, Wiley, Vol. 4, No. 10 ( 2011-10), p. 759-767
Abstract:
Bruises become spatially inhomogeneous during the healing process; a smaller red‐blue core area, caused by hemoglobin, is surrounded by a larger yellow area, caused by bilirubin, which is enzymatically formed from hemoglobin. These two areas develop at different rates and hence carry information about the age of the bruise. We present a proof of principle demonstration that the age of bruises can be determined via an inverse procedure using a mathematical model and daily measurements of these two areas using a hyperspectral imaging system. The inaccuracy found is 2.3% for fresh bruises and 3 to 24% for bruises up to 3 days old. In conclusion, color inhomogeneity of bruises can be used to determine their age. We expect that future age determination of bruises by the inverse procedure described here, possibly also including the distribution of concentrations in the areas will open up a new phase in clinical bruise classification. (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Type of Medium:
Online Resource
ISSN:
1864-063X
,
1864-0648
DOI:
10.1002/jbio.201100021
Language:
English
Publisher:
Wiley
Publication Date:
2011
detail.hit.zdb_id:
2403788-6
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