X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    Understanding the Vicious Circle of Pain, Physical Activity, and Mental Health in Lipedema Patients—A Response Surface Analysis
    MDPI AG ; 2023
    In:  Journal of Clinical Medicine Vol. 12, No. 16 ( 2023-08-16), p. 5319-
    Details
    In: Journal of Clinical Medicine, MDPI AG, Vol. 12, No. 16 ( 2023-08-16), p. 5319-
    Abstract: Lipedema is a widespread disease with painful accumulations of subcutaneous fat in the legs and arms. Often, obesity co-occurs. Many patients suffer from impairment in mobility and mental health. Obesity and mental health in turn can be positively influenced by physical activity. In this study, we aimed to examine the interrelations between pain and physical activity on mental health in lipedema patients. In total, 511 female lipedema patients (age M = 40.16 ± 12.45 years, BMI M = 33.86 ± 7.80 kg/m2) filled in questionnaires measuring pain, physical activity, and mental health (PHQ-9; WHOQOL-BREF with subscales mental, physical, social, environmental, and overall health). Response surface analyses were calculated via R statistics. The explained variance was high for the model predicting depression severity (R2 = 0.18, p 〈 0.001) and physical health (R2 = 0.30, p 〈 0.001). Additive incongruence effects of pain and physical activity on depression severity, mental, physical, and overall health were found (all p 〈 0.001). In our study, physical activity and pain synergistically influenced physical, mental, and overall health. The pain not only led to low mental health but also interfered with the valuable potential of engaging in physical activity in lipedema patients.
    Type of Medium: Online Resource
    ISSN: 2077-0383
    URL: Article
    DOI: 10.3390/jcm12165319
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2662592-1
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 2
    Online Resource
    Online Resource
    Patient-Reported Outcomes of Liposuction for Lipedema Treatment
    MDPI AG ; 2023
    In:  Healthcare Vol. 11, No. 14 ( 2023-07-13), p. 2020-
    Details
    In: Healthcare, MDPI AG, Vol. 11, No. 14 ( 2023-07-13), p. 2020-
    Abstract: Background: Lipedema, as a disabling and consequential disease, is gaining more awareness due to its potential omnipresence. Patients suffering from lipedema show a characteristic painful display of symmetric accumulations of adipose tissue. The combination of swelling, pain and decreased quality of life (QOL) is outstanding for the diagnosis. The aim of this study was to identify the effect of liposuction in terms of the QOL for patients and underline important factors of current and pending research regarding surgical therapy of lipoedema. Methods: Patients suffering from lipedema prior to and after receiving liposuction at our hospital were included in this study. Patients completed a lipedema-specific self-designed 50 item questionnaire: the World Health Organization Quality of Life BREF (WHOQOL-BREF) and the Patient Health Questionnaire 9 (PHQ-9). A linear mixed model was used for outcome analysis. Results: In total, 511 patients completed a questionnaire prior to the surgery at primary presentation to the hospital and a total number of 56 patients completed a questionnaire after liposuction. A total of 34 of these patients filled in both questionnaires prior to and after surgery. The general characteristics of the disease, such as daily symptoms and psychological health, pertinently improved after surgery. Conclusions: Liposuction can have a general improving effect on the QOL of patients, both in private and professional life. Liposuction may currently be the most evident and promising method in the treatment of lipedema.
    Type of Medium: Online Resource
    ISSN: 2227-9032
    URL: Article
    DOI: 10.3390/healthcare11142020
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2721009-1
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 3
    Online Resource
    Online Resource
    Complication Rates after Breast Surgery with the Motiva Smooth Silk Surface Silicone Gel Implants—A Systematic Review and Meta-Analysis
    MDPI AG ; 2023
    In:  Journal of Clinical Medicine Vol. 12, No. 5 ( 2023-02-27), p. 1881-
    Details
    In: Journal of Clinical Medicine, MDPI AG, Vol. 12, No. 5 ( 2023-02-27), p. 1881-
    Abstract: Background: In an era where textured devices are being phased out due to concerns about BIA-ALCL, the Motiva SilkSurface breast implants intend to alleviate historical prosthesis-related complications. However, its safety and feasibility remain unelucidated. Methods: An analysis of Pubmed, Web of Science, Ovid, and Embase databases was performed. A total of 114 studies were identified initially, and 13 of these met the inclusion criteria and were assessed regarding postoperative parameters such as complication rate or follow-up period. Results: In 4784 patients who underwent breast augmentation with Motiva SilkSurface breast implants, a total of 250 (5.2%) complications were observed. Short- and medium-term complication rates ranged from 2.8–14.4% and 0.32–16.67%, respectively. The most common complication was early seroma (n = 52, overall incidence = 1.08%), followed by early hematoma (n = 28, overall incidence = 0.54%). The incidence of capsule contracture was 0.54% and breast implant-associated-anaplastic large cell lymphoma was not observed. Discussion: Although the majority of the studies in the current literature suggest the distinction of the Motiva SilkSurface breast implants in terms of postoperative complications and capsular contracture, its safety and feasibility need to be further elucidated with well-designed, large-scale, multicenter, prospective case-control studies. Other: No funding was received.
    Type of Medium: Online Resource
    ISSN: 2077-0383
    URL: Article
    DOI: 10.3390/jcm12051881
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2662592-1
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 4
    Online Resource
    Online Resource
    Liposuktion beim Lipödem – Doch besser als ihr Ruf?
    Wiley ; 2023
    In:  JDDG: Journal der Deutschen Dermatologischen Gesellschaft Vol. 21, No. 6 ( 2023-06), p. 601-610
    Details
    In: JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Wiley, Vol. 21, No. 6 ( 2023-06), p. 601-610
    Abstract: Das Lipödem ist eine häufige chronische Fettverteilungsstörung, die oft mit Schmerzen und eingeschränkter Lebensqualität einhergeht und 6% bis 10% der weiblichen Bevölkerung betrifft. Obwohl das Lipödem in den letzten zehn Jahren mehr wissenschaftliche Aufmerksamkeit erhalten hat, bleiben validierte Diagnose und Behandlung für Spezialisten eine Herausforderung. Patienten und Methodik In diesem Artikel werden die Auswirkungen der Fettabsaugung auf Aussehen, Schmerzen und Begleiterkrankungen von 860 Patienten mit Lipödemen untersucht. Die Symptome von Patienten mit unterschiedlichen Stadien des Lipödems wurden mittels t‐Tests für unabhängige Stichproben und Kruskal‐Wallis‐Tests vor und nach der Liposuktion verglichen. Ergebnisse Unsere Studie belegt den positiven Effekt auf die Schmerzreduktion bei Patienten mit Lipödem nach der Liposuktion (NRS 2,24) im Vergleich zum Schmerzempfinden vor der Liposuktion (NRS 6,99) und zum Schmerzempfinden von Patienten mit konservativer Behandlung (NRS 6,26). Es zeigten sich signifikante Unterschiede in der Wahrnehmung zwischen den Stadien des Lipödems sowie signifikante Verringerung des Schmerzempfindens durch die Liposuktion. Außerdem zeigten Patienten mit Lipödem Begleiterkrankungen wie Menstruationsbeschwerden (43%), Schlaflosigkeit (36%) und Migräne (35%). Schlussfolgerungen Ein Fortschreiten des Lipödems führt nicht nur zu Veränderungen des Aussehens und der Proportionen, sondern auch zur progressiven Zunahme der Schmerzen. Die Liposuktion zeigt als einzige Therapieoption einen signifikanten Effekt auf die Schmerzreduktion ‐ unabhängig vom Stadium des Lipödems der Patienten.
    Type of Medium: Online Resource
    ISSN: 1610-0379 , 1610-0387
    URL: Issue
    URL: Article
    DOI: 10.1111/ddg.v21.6
    DOI: 10.1111/ddg.15064_g
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2099463-1
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 5
    Online Resource
    Online Resource
    Breaking the circle‐effectiveness of liposuction in lipedema
    Wiley ; 2023
    In:  JDDG: Journal der Deutschen Dermatologischen Gesellschaft Vol. 21, No. 6 ( 2023-06), p. 601-609
    Details
    In: JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Wiley, Vol. 21, No. 6 ( 2023-06), p. 601-609
    Abstract: Lipedema is a common chronic fat distribution disorder often aligned with pain and reduced quality of life affecting 6–10% of the female population. Although lipedema has acquired more scientific attention in the last decade, validated diagnosis and treatment still remain challenging for specialists. Patients and Methods In this article we evaluate the effect of liposuction on appearance, pain and coexisting diseases of 860 patients with lipedema. Comparison among stages of lipedema pre‐ and post‐liposuction was performed by using t‐Tests for independent samples and Kruskal‐Wallis‐Tests. Results Our study demonstrates the positive effect on pain reduction in patients with lipedema after liposuction (NRS 2.24) compared with pre‐liposuction pain perception (NRS 6.99) and pain perception of patients with conservative treatment (NRS 6.26). Significant differences were shown in the perception between the stages of lipedema and in the reduction of pain perception by liposuction. Furthermore we examined co‐diseases in patients with lipedema, primarily menstruation complaints (43%), sleeplessness (36%) and migraine (35%). Conclusions A progress of lipedema disease leads not only to a change of appearance and proportion but also to a progressive increase of pain. Liposuction shows a significant effect on pain reduction ‐independent of the patients’ stage of lipedema.
    Type of Medium: Online Resource
    ISSN: 1610-0379 , 1610-0387
    URL: Issue
    URL: Article
    DOI: 10.1111/ddg.v21.6
    DOI: 10.1111/ddg.15064
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2099463-1
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 6
    Online Resource
    Online Resource
    Factors Influencing Quality of Life after Massive Weight Loss—What Makes the Difference?
    MDPI AG ; 2023
    In:  Healthcare Vol. 11, No. 8 ( 2023-04-17), p. 1147-
    Details
    In: Healthcare, MDPI AG, Vol. 11, No. 8 ( 2023-04-17), p. 1147-
    Abstract: Although weight reduction in obesity and morbid obesity has been shown to improve associated comorbidities, there is currently no information on what influences quality of life after a large reduction in body weight. The present study looks at differences in patients’ quality of life classified by mode and amount of weight loss. Material and methods: A cross-sectional study was designed using a validated German version of the BODY-Q questionnaire. The internet-based questionnaire was distributed to patients via social media. Results: 460 patients (443 female, 17 male) were interviewed for this study via “Surveymonkey”. The comparison of conservative and surgical weight loss showed no significant difference in the patients’ quality of life (p 〉 0.05). A high BMI correlates negatively with body image (p = 0.023 *), as does the specific assessment of most body regions. For example, a negative correlation was found between a high BMI and satisfaction with skin appearance (p 〈 0.001 *) and satisfaction with the inner thigh (p = 0.011 *). Conclusion: Increased weight loss is associated with a greater ability to maximise quality of life. The type of weight loss, whether conservative or surgical, can be neglected based on the present study. Bariatric surgery cannot be considered a universal solution to obesity. Body contouring interventions should also become a focus of therapy.
    Type of Medium: Online Resource
    ISSN: 2227-9032
    URL: Article
    DOI: 10.3390/healthcare11081147
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2721009-1
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 7
    Online Resource
    Online Resource
    Three-Loop Technique for Pulley Reconstruction—A Retrospective Cohort Analysis of 23 Patients
    MDPI AG ; 2023
    In:  Journal of Clinical Medicine Vol. 12, No. 15 ( 2023-08-07), p. 5154-
    Details
    In: Journal of Clinical Medicine, MDPI AG, Vol. 12, No. 15 ( 2023-08-07), p. 5154-
    Abstract: Twenty-three patients with a mean age of 52.7 years underwent pulley reconstruction using the Okutsu double- or triple-loop technique after iatrogenic or traumatic rupture of at least two adjacent flexor tendon pulleys in the finger and distal palm; mean age of injury was 4.77 years. The mean follow-up was 4.66 years after reconstruction of mostly A2 pulleys in a single surgeon setting. Outcome measures included ROM, NRS pain, satisfaction, Disabilities of Arm, Shoulder and Hand Questionnaire (DASH) and Krimmer score, Buck–Gramcko score, Jamar grip strength, pinch grip, and vigorimetry compared to the uninjured side. The median patient satisfaction score was 6.6/10. Hand function using the DASH score was 9.5. Grip strength on the Jamar Dynamometer showed only a slight reduction of 13% compared to the uninjured side. The resultant force of the operated fingers on the vigorimeter is almost 60% of that of the contralateral side, and the finger-palm distance of the operated finger was reduced from 2.2 cm to 1.45 cm. Other functional scores, such as Krimmer (82.2) and Buck-Gramcko (10.9), support these good results. The follow-up of patients more than 4.5 years after reconstruction of the A2 and A3 flexor tendon pulley using the double- or triple-loop technique showed acceptable patient satisfaction and good function of the finger in everyday life.
    Type of Medium: Online Resource
    ISSN: 2077-0383
    URL: Article
    DOI: 10.3390/jcm12155154
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2662592-1
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 8
    Online Resource
    Online Resource
    Characteristics and Patient Reported Outcome Measures in Lipedema Patients—Establishing a Baseline for Treatment Evaluation in a High-Volume Center
    MDPI AG ; 2022
    In:  Journal of Clinical Medicine Vol. 11, No. 10 ( 2022-05-17), p. 2836-
    Details
    In: Journal of Clinical Medicine, MDPI AG, Vol. 11, No. 10 ( 2022-05-17), p. 2836-
    Abstract: Lipedema patients suffer not only from visual stigma but also reduction in their quality of life through pain and performance loss in daily life. In clinical practice, it is still difficult to reliably diagnose the disease. This study aims to provide further insights into the characteristics of lipedema patients of all stages and provide a baseline prior to surgery for a surgical treatment evaluation by means of patient-reported outcome measures. Methods: Patients completed a lipedema-specific questionnaire containing 50 items, the World Health Organization Quality of Life BREF (WHOQOL-BREF) and the Patient Health Questionnaire 9 (PHQ-9). The data were analyzed using SPSS statistics 27. Patients who had already received liposuction were excluded. Results: Five hundred and eleven patients were included, of whom 337 completed the PHQ9 and 333 completed the WHOQOL-BREF questionnaires. The general characteristics of lipedema patients, especially the daily symptoms, are described. Previous observations, such as the frequent occurrence of hypothyroidism and the low rate of type 2 diabetes, were confirmed. Over 49% suffer from severe impairments in their jobs, whereby the disease shows a familial accumulation. The results of the WHOQOL-BREF and the PHQ-9 suggest a high level of mental stress. Discussion: As surgical intervention in lipedema patients is gaining traction, its effects should be well-documented. Therefore, a comprehensive baseline needs to be established prior to surgical treatment. The psychological components are just as important as the inclusion of daily impairments.
    Type of Medium: Online Resource
    ISSN: 2077-0383
    URL: Article
    DOI: 10.3390/jcm11102836
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2662592-1
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 9
    Online Resource
    Online Resource
    Understanding Breast Implant Illness: Etiology is the Key
    Oxford University Press (OUP) ; 2022
    In:  Aesthetic Surgery Journal Vol. 42, No. 4 ( 2022-03-15), p. 370-377
    Details
    In: Aesthetic Surgery Journal, Oxford University Press (OUP), Vol. 42, No. 4 ( 2022-03-15), p. 370-377
    Abstract: Because breast augmentation is one of the most popular cosmetic procedures, the issue of implant-related complications has been widely debated ever since the FDA approved the use of implants in 1962. Although decades have passed, breast implant illness (BII) still represents a poorly defined and controversial complication. With ongoing nonscientific discussion in the mainstream media and on social media, revealing the etiology of BII is urgent because knowledge of this subject ultimately influences patients’ decisions. Little or no scientific research is currently available on BII and no final conclusions regarding its etiology, clinical manifestations, diagnostic criteria, or treatment have been made. This review aims to give an overview of the hypotheses on the etiology of BII and seeks inspiration to improve the conditions of BII patients.
    Type of Medium: Online Resource
    ISSN: 1090-820X , 1527-330X
    URL: Article
    DOI: 10.1093/asj/sjab197
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2022
    detail.hit.zdb_id: 2048788-5
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
  • 10
    Online Resource
    Online Resource
    Transgenic skin biomechanical properties following first lifesaving epidermal regeneration using combined gene and cell therapy
    Wiley ; 2023
    In:  JDDG: Journal der Deutschen Dermatologischen Gesellschaft Vol. 21, No. 3 ( 2023-03), p. 245-252
    Details
    In: JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Wiley, Vol. 21, No. 3 ( 2023-03), p. 245-252
    Abstract: In 2017, we reported the first life‐saving regeneration of virtually an entire epidermis by combined gene and stem cell therapy. Recently, we demonstrated excellent long‐term stability of this transgenic epidermis. Skin quality in this experimental approach and its potential application in other conditions were elucidated here regarding long‐term outcomes of biomechanical properties. Patients and methods Analysis of biomechanical properties including skin elasticity, anisotropy and friction was performed on multiple body sites 24, 36 and 60 months following transplantation. Firstly, the sites were matched against and compared to remaining stable non‐transgenic areas as well as to a control group of 13 healthy subjects. Parameters for skin elasticity, deformation and friction were assessed non‐invasively. Results Biomechanical properties of the transgenic epidermis showed encouraging results in comparison to both the remaining stable non‐transgenic skin as well as healthy controls. Skin elasticity was comparable to the controls. Skin friction showed some decrease in both transgenic and non‐transgenic areas as compared to the controls. Conclusions The excellent functional outcomes of the transgenic epidermis demonstrate stable long‐term results of this novel combined gene and stem cell therapy for epidermal regeneration. Thus, other applications for this technology, such as treatment of specific burns, should be explored.
    Type of Medium: Online Resource
    ISSN: 1610-0379 , 1610-0387
    URL: Issue
    URL: Article
    DOI: 10.1111/ddg.v21.3
    DOI: 10.1111/ddg.14978
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2099463-1
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Online Resource
    Open Access Request
    Availability (electronic / print)
Nothing or not found what you are looking for? Please check your search query or use the Interlibrary Loan Search.
Close ⊗
This website uses cookies and the analysis tool Matomo. Further information can be found on the KOBV privacy pages