In:
Epilepsia Open, Wiley, Vol. 2, No. 2 ( 2017-06), p. 260-266
Abstract:
We investigated the relationship between the scalp distribution of fast (40–150 Hz) oscillations ( FO s) and epileptogenic lesions in West syndrome ( WS ) and related disorders. Subjects were 9 pediatric patients with surgically confirmed structural epileptogenic pathology (age at initial electroencephalogram [ EEG ] recording: mean 7.1 months, range 1–22 months). The diagnosis was WS in 7 patients, Ohtahara syndrome in 1, and a transitional state from Ohtahara syndrome to WS in the other. In the scalp EEG data of these patients, we conservatively detected FO s, and then examined the distribution of FO s. In five patients, the scalp distribution of FO s was consistent and concordant with the lateralization of cerebral pathology. In another patient, FO s were consistently dominant over the healthy cerebral hemisphere, and the EEG was relatively low in amplitude over the pathological atrophic hemisphere. In the remaining 3 patients, the dominance of FO s was inconsistent and, in 2 of these patients, the epileptogenic hemisphere was reduced in volume, which may result from atrophy or hypoplasia. The correspondence between the scalp distribution of FO s and the epileptogenic lesion should be studied, taking the type of lesion into account. The factors affecting scalp FO s remain to be elucidated.
Type of Medium:
Online Resource
ISSN:
2470-9239
,
2470-9239
DOI:
10.1002/epi4.2017.2.issue-2
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
2863427-5
Bookmarklink