In:
Tumori Journal, SAGE Publications, Vol. 77, No. 6 ( 1991-12), p. 460-464
Abstract:
We have examined the possibility of obtaining primary cultures from breast tissue utilizing a method especially developed for breast epithelium. The number of specimens able to grow in culture was very high: 82.8%, 64.3 %, 75.0 % and 77.8 %, respectively, for primary breast cancer, skin recurrences, inflammatory breast cancer and normal breast tissue. In our experience, growth was not related to menopausal status or histopathologic type, whereas for skin recurrences, a prior pharmacologic treatment (chemotherapy) of the patient enhanced the growth capacity of the tissue. This culture method could help to study the basic biology of breast epithelia and to improve the chemotherapy approach of breast cancer patients.
Type of Medium:
Online Resource
ISSN:
0300-8916
,
2038-2529
DOI:
10.1177/030089169107700602
Language:
English
Publisher:
SAGE Publications
Publication Date:
1991
detail.hit.zdb_id:
280962-X
detail.hit.zdb_id:
2267832-3
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