In:
European Journal of Organic Chemistry, Wiley, Vol. 2013, No. 29 ( 2013-10), p. 6501-6505
Abstract:
This work describes the design, synthesis, and application of de novo chiral fluorinating agents as analogues of popular N ‐fluorodibenzenesulfonimide (NFSI). The fluorination step by means of elemental fluorine is presented. Enantioselective fluorination is demonstrated in cyclic β‐keto esters and in the synthesis of BMS‐204352 (up to 86 % ee ). Oxidative aminofluorination is also examined.
Type of Medium:
Online Resource
ISSN:
1434-193X
,
1099-0690
DOI:
10.1002/ejoc.v2013.29
DOI:
10.1002/ejoc.201300956
Language:
English
Publisher:
Wiley
Publication Date:
2013
detail.hit.zdb_id:
1475010-7
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