In:
Clinical Transplantation, Wiley, Vol. 31, No. 11 ( 2017-11)
Abstract:
Takotsubo syndrome ( TTS ), also known as Takotsubo cardiomyopathy or stress‐induced cardiomyopathy, has been described following a variety of surgeries and disease states. The relationship between intra‐operative anesthesia management and the development of this syndrome has never been fully elucidated. Objectives The primary objective of this study was to determine the relationship of multiple intra‐operative factors on the pathogenesis of TTS . Methods A single‐center retrospective review of all liver transplants performed at Mayo Clinic Florida from January 2005 to December 2014. Patients developing left ventricular dilation and a concomitant decrease in ejection fraction, a negative cardiac catheterization, or stress test within 30 days of transplantation were identified. Cases were matched 2:1 to controls with respect to MELD , age, sex, and indication for transplantation. Our evaluation included liver graft characteristics, intra‐operative medications, and intra‐operative hemodynamic measurements. Results We identified 24 cases of TTS from a pool of 1752 transplants, for an incidence of 1.4%. No statistically significant differences in intra‐operative measures between the two groups were identified (all P ≥ .08). Conclusion Our exploratory, single‐center retrospective review evaluating 46 intra‐operative characteristics found no association with the development of TTS .
Type of Medium:
Online Resource
ISSN:
0902-0063
,
1399-0012
DOI:
10.1111/ctr.2017.31.issue-11
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
2739458-X
detail.hit.zdb_id:
2004801-4
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