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A Comparative Analysis of Drug-Induced Hepatotoxicity in Clinically Relevant Situations

Thiel, Christoph ; Cordes, Henrik ; Fabbri, Lorenzo ; [et al.]

Public Library of Science (PLoS) ; 2017

In: PLOS Computational Biology Vol. 13, No. 2 ( 2017-2-2), p. e1005280-

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In: PLOS Computational Biology, Public Library of Science (PLoS), Vol. 13, No. 2 ( 2017-2-2), p. e1005280-

Type of Medium: Online Resource

ISSN: 1553-7358

URL: Article

DOI: 10.1371/journal.pcbi.1005280

DOI: 10.1371/journal.pcbi.1005280.g001

DOI: 10.1371/journal.pcbi.1005280.g002

DOI: 10.1371/journal.pcbi.1005280.g003

DOI: 10.1371/journal.pcbi.1005280.g004

DOI: 10.1371/journal.pcbi.1005280.g005

DOI: 10.1371/journal.pcbi.1005280.g006

DOI: 10.1371/journal.pcbi.1005280.g007

DOI: 10.1371/journal.pcbi.1005280.g008

DOI: 10.1371/journal.pcbi.1005280.g009

DOI: 10.1371/journal.pcbi.1005280.t001

DOI: 10.1371/journal.pcbi.1005280.t002

DOI: 10.1371/journal.pcbi.1005280.s001

DOI: 10.1371/journal.pcbi.1005280.s002

DOI: 10.1371/journal.pcbi.1005280.s003

DOI: 10.1371/journal.pcbi.1005280.s004

DOI: 10.1371/journal.pcbi.1005280.s005

DOI: 10.1371/journal.pcbi.1005280.s006

DOI: 10.1371/journal.pcbi.1005280.s007

DOI: 10.1371/journal.pcbi.1005280.s008

DOI: 10.1371/journal.pcbi.1005280.s009

DOI: 10.1371/journal.pcbi.1005280.s010

DOI: 10.1371/journal.pcbi.1005280.s011

DOI: 10.1371/journal.pcbi.1005280.s012

DOI: 10.1371/journal.pcbi.1005280.s013

DOI: 10.1371/journal.pcbi.1005280.s014

DOI: 10.1371/journal.pcbi.1005280.s015

DOI: 10.1371/journal.pcbi.1005280.s016

DOI: 10.1371/journal.pcbi.1005280.s017

DOI: 10.1371/journal.pcbi.1005280.s018

DOI: 10.1371/journal.pcbi.1005280.s019

Language: English

Publisher: Public Library of Science (PLoS)

Publication Date: 2017

detail.hit.zdb_id: 2193340-6

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DataSheet1.docx

Aschmann, Hélène Eloise ; Domenghino, Anja ; Jung, Ruedi ; [et al.]

Frontiers Media SA ; 2024

In: International Journal of Public Health Vol. 69 ( 2024-9-24)

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In: International Journal of Public Health, Frontiers Media SA, Vol. 69 ( 2024-9-24)

Abstract: Before vaccines and effective treatments were available, quarantine of close contacts was important to limit the spread of SARS-CoV-2. To evaluate potential benefits and harms of quarantine, we aimed to estimate infection rates and describe experiences and mental health among persons in mandated quarantine during the early SARS-CoV-2 pandemic. Methods We invited adults in mandated quarantine after an exposure to SARS-CoV-2 identified through contact tracing of the Canton of Zurich, Switzerland, between August 2020 and January 2021. Participants completed two questionnaires and received up to two SARS-CoV-2 polymerase chain reaction tests, during and at the end of quarantine. Results Among 395 participants, quarantine duration ranged from 2 to 20 days. By day 11 since the last contact, 11.1% [95% CI 8.4%–14.7%] were infected with SARS-CoV-2. The proportion of participants with symptoms of depression doubled from 9.3% before quarantine to 18.9% during quarantine, and 12.1% reported quarantine was very or extremely difficult. Conclusion Although quarantine was only moderately burdensome for most participants, some experienced significant difficulties and burden. Policymakers need to balance infection control with potential harms placed on individuals.

Type of Medium: Online Resource

ISSN: 1661-8564

URL: Article

DOI: 10.3389/ijph.2024.1606221

DOI: 10.3389/ijph.2024.1606221.s001

Language: Unknown

Publisher: Frontiers Media SA

Publication Date: 2024

detail.hit.zdb_id: 2276416-1

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Krebs Screening : Voraussetzungen für ein sinnvolles und erfolgreiches Programm

Aschmann, Hélène Eloise ; Puhan, Milo Alan

Hogrefe Publishing Group ; 2021

In: Therapeutische Umschau Vol. 78, No. 2 ( 2021-03), p. 55-60

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In: Therapeutische Umschau, Hogrefe Publishing Group, Vol. 78, No. 2 ( 2021-03), p. 55-60

Abstract: Zusammenfassung. Nutzen und Schaden von Krebs-Screening müssen sorgfältig aufgrund von wissenschaftlicher Evidenz beurteilt, in Kontext gesetzt und gegeneinander abgewogen werden. Der Erfolg von Krebs-Screening-Programmen hängt aber von vielen weiteren Faktoren ab, wie von der Teilnahmerate, der Organisation und der Qualität des Programmes. Dieser Artikel erläutert die epidemiologischen Voraussetzungen, damit ein Krebs-Screening sinnvoll sein kann, und wie ein erfolgreiches Screening-Programm gestaltet sein muss.

Type of Medium: Online Resource

ISSN: 0040-5930 , 1664-2864

URL: Article

DOI: 10.1024/0040-5930/a001239

Language: German

Publisher: Hogrefe Publishing Group

Publication Date: 2021

detail.hit.zdb_id: 82044-1

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